Methoxyeugenol deactivates hepatic stellate cells and attenuates liver fibrosis and inflammation through a PPAR-ɣ and NF-kB mechanism

Modulating Tumor-Associated Macrophage Polarization by Synthetic and Natural PPARγ Ligands as a Potential Target in Breast Cancer

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Resveratrol increases the activation markers and changes the release of inflammatory cytokines of hepatic stellate cells

(2020) Cleverson Moraes de Oliveira et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Protective Effect of Myristica fragrans Houtt. Extracts Against Obesity and Inflammation by Regulating Free Fatty Acids Metabolism in Nonalcoholic Fatty Liver Disease

(2020) Wenyu Zhao et al.   Nutrients

Methoxyeugenol regulates the p53/p21 pathway and suppresses human endometrial cancer cell proliferation

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Role of PPAR receptor in different diseases and their ligands: Physiological importance and clinical implications

(2019) Agha Zeeshan Mirza et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Docosahexaenoic acid inhibits hepatic stellate cell activation to attenuate liver fibrosis in a PPARγ-dependent manner

(2019) Jianlin He et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hepatoprotective and antineoplastic potencial of red propolis produced by the bees Apis mellifera in the semiarid of Rio Grande do Norte, Brazil

(2019) Jardel B. Silva et al.   PESQUISA VETERINARIA BRASILEIRA

Hepatoprotective effect of Forsythiae Fructus water extract against carbon tetrachloride-induced liver fibrosis in mice

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Resveratrol alleviates FFA and CCl4 induced apoptosis in HepG2 cells via restoring endoplasmic reticulum stress

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Piperine Attenuates Pathological Cardiac Fibrosis Via PPAR-γ/AKT Pathways

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Mangiferin Inhibits IL-1β-Induced Inflammatory Response by Activating PPAR-γ in Human Osteoarthritis Chondrocytes

(2016) Yanlong Qu et al.   INFLAMMATION

Sinusoidal communication in liver fibrosis and regeneration

(2016) Giusi Marrone et al.   JOURNAL OF HEPATOLOGY

Hepatoprotective Activity of an Herbal Composition, MAP, a Standardized Blend Comprising Myristica fragrans, Astragalus membranaceus, and Poria cocos

(2016) Mesfin Yimam et al.   JOURNAL OF MEDICINAL FOOD

Chemical diversity and pharmacological significance of the secondary metabolites of nutmeg (Myristica fragrans Houtt.)

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Biological Properties and Therapeutic Applications of Propolis

(2016) José M. Sforcin   PHYTOTHERAPY RESEARCH

Peroxisome proliferator-activated receptor (PPAR) gamma in cardiovascular disorders and cardiovascular surgery

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Oleoylethanolamide, an endogenous PPAR-α ligand, attenuates liver fibrosis targeting hepatic stellate cells

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Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review

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18α-glycyrrhetinic acid extracted fromGlycyrrhiza radixinhibits proliferation and promotes apoptosis of the hepatic stellate cell line

(2013) Lei Zong et al.   Journal of Digestive Diseases

Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol mediated liver fibrosis in mice

(2013) Yue-Min Nan et al.   Lipids in Health and Disease

CD163 and Inflammation: Biological, Diagnostic, and Therapeutic Aspects

(2012) Anders Etzerodt et al.   ANTIOXIDANTS & REDOX SIGNALING

Essential oil ofMyrica esculentaBuch. Ham.: composition, antimicrobial and topical anti-inflammatory activities

(2012) Supriya Agnihotri et al.   NATURAL PRODUCT RESEARCH

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(2011) Virginia Hernandez-Gea et al.   Annual Review of Pathology-Mechanisms of Disease

Brazilian red propolis: unreported substances, antioxidant and antimicrobial activities

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NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma

(2011) Tom Luedde et al.   Nature Reviews Gastroenterology & Hepatology

Polyphenols: Chemistry, Dietary Sources, Metabolism, and Nutritional Significance

(2010) Laura Bravo   NUTRITION REVIEWS

Mechanisms of liver disease: cross-talk between the NF-κB and JNK pathways

(2009) Salvatore Papa et al.   BIOLOGICAL CHEMISTRY

Targeting liver fibrosis: Strategies for development and validation of antifibrotic therapies

(2009) Yury Popov et al.   HEPATOLOGY

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Defining therapeutic targets for liver fibrosis: Exploiting the biology of inflammation and repair

(2008) J IREDALE   PHARMACOLOGICAL RESEARCH