Coordination of rigidity modulation and targeting ligand modification on orally-delivered nanoparticles for the treatment of liver fibrosis

Nanoparticle elasticity regulates phagocytosis and cancer cell uptake

(2020) Yue Hui et al.   Science Advances

Tailored elasticity combined with biomimetic surface promotes nanoparticle transcytosis to overcome mucosal epithelial barrier

(2020) Yaxian Zheng et al.   BIOMATERIALS

Temperature- and rigidity-mediated rapid transport of lipid nanovesicles in hydrogels

(2019) Miaorong Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transferrin Functionization Elevates Transcytosis of Nanogranules across Epithelium by Triggering Polarity-Associated Transport Flow and Positive Cellular Feedback Loop

(2019) Dan Yang et al.   ACS Nano

Enzyme-activatable polymer–drug conjugate augments tumour penetration and treatment efficacy

(2019) Quan Zhou et al.   Nature Nanotechnology

Cross-linker-Modulated Nanogel Flexibility Correlates with Tunable Targeting to a Sterically Impeded Endothelial Marker

(2019) Jacob Wheatley Myerson et al.   ACS Nano

Multivalent HER2-binding polymer conjugates facilitate rapid endocytosis and enhance intracellular drug delivery

(2019) D. Christopher Radford et al.   JOURNAL OF CONTROLLED RELEASE

Novel Solid Lipid Nanoparticle with Endosomal Escape Function for Oral Delivery of Insulin

(2018) Yining Xu et al.   ACS Applied Materials & Interfaces

Engineering nanomaterials to overcome the mucosal barrier by modulating surface properties

(2018) Lei Wu et al.   ADVANCED DRUG DELIVERY REVIEWS

Flexible Nanoparticles Reach Sterically Obscured Endothelial Targets Inaccessible to Rigid Nanoparticles

(2018) Jacob W. Myerson et al.   ADVANCED MATERIALS

Receptor mediated transcytosis in biological barrier: The influence of receptor character and their ligand density on the transmembrane pathway of active-targeting nanocarriers

(2018) Xiaoning Song et al.   BIOMATERIALS

Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers

(2018) Miaorong Yu et al.   Nature Communications

Peptide density targets and impedes triple negative breast cancer metastasis

(2018) Daxing Liu et al.   Nature Communications

Iron-mimic peptide converts transferrin from foe to friend for orally targeting insulin delivery

(2018) Min Liu et al.   Journal of Materials Chemistry B

Multifunctional Nanoparticles Enable Efficient Oral Delivery of Biomacromolecules via Improving Payload Stability and Regulating the Transcytosis Pathway

(2018) Yaxian Zheng et al.   ACS Applied Materials & Interfaces

Tandem Enzymatic Self-Assembly and Slow Release of Dexamethasone Enhances Its Antihepatic Fibrosis Effect

(2018) Wei Tang et al.   ACS Nano

Membrane Wrapping Efficiency of Elastic Nanoparticles during Endocytosis: Size and Shape Matter

(2018) Zhiqiang Shen et al.   ACS Nano

Kinetics of receptor-mediated endocytosis of elastic nanoparticles

(2017) Xin Yi et al.   Nanoscale

Functionalized materials for multistage platforms in the oral delivery of biopharmaceuticals

(2017) Francisca Araújo et al.   PROGRESS IN MATERIALS SCIENCE

Antibody fragments as nanoparticle targeting ligands: a step in the right direction

(2017) Daniel A. Richards et al.   Chemical Science

A comprehensive review of the neonatal Fc receptor and its application in drug delivery

(2016) João Pedro Martins et al.   PHARMACOLOGY & THERAPEUTICS

Fluorescent cell-traceable dexamethasone-loaded liposomes for the treatment of inflammatory liver diseases

(2015) Matthias Bartneck et al.   BIOMATERIALS

Effect of surface chemistry on nanoparticle interaction with gastrointestinal mucus and distribution in the gastrointestinal tract following oral and rectal administration in the mouse

(2015) Katharina Maisel et al.   JOURNAL OF CONTROLLED RELEASE

Tunable Rigidity of (Polymeric Core)-(Lipid Shell) Nanoparticles for Regulated Cellular Uptake

(2014) Jiashu Sun et al.   ADVANCED MATERIALS

Effect of Polyplex Morphology on Cellular Uptake, Intracellular Trafficking, and Transgene Expression

(2013) Julie Shi et al.   ACS Nano

Matrix Metalloproteinase Responsive, Proximity-Activated Polymeric Nanoparticles for siRNA Delivery

(2013) Hongmei Li et al.   ADVANCED FUNCTIONAL MATERIALS

The transport mechanisms of polymer nanoparticles in Caco-2 epithelial cells

(2013) Bing He et al.   BIOMATERIALS

Steroid use in acute liver failure

(2013) Jamuna Karkhanis et al.   HEPATOLOGY

Nanoparticle Adhesion to the Cell Membrane and Its Effect on Nanoparticle Uptake Efficiency

(2013) Anna Lesniak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transferrin receptor specific nanocarriers conjugated with functional 7peptide for oral drug delivery

(2012) Wenwen Du et al.   BIOMATERIALS

Drug targeting to the diseased liver

(2012) Klaas Poelstra et al.   JOURNAL OF CONTROLLED RELEASE

Mass Production and Size Control of Lipid–Polymer Hybrid Nanoparticles through Controlled Microvortices

(2012) YongTae Kim et al.   NANO LETTERS

Oral drug delivery with polymeric nanoparticles: The gastrointestinal mucus barriers

(2011) Laura M. Ensign et al.   ADVANCED DRUG DELIVERY REVIEWS

Cellular Uptake of Elastic Nanoparticles

(2011) Xin Yi et al.   PHYSICAL REVIEW LETTERS

The delivery of endocytosed cargo to lysosomes: Figure 1

(2009) J. Paul Luzio et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Dendrimer-Based Contrast Agents for Molecular Imaging

(2008) Michelle Longmire et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

A peptide-targeted delivery system with pH-sensitive amphiphilic cell membrane disruption for efficient receptor-mediated siRNA delivery

(2008) Xu-Li Wang et al.   JOURNAL OF CONTROLLED RELEASE

Reduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn

(2008) A. R. Mezo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA