Iron-mimic peptide converts transferrin from foe to friend for orally targeting insulin delivery

Enhanced Oral Delivery of Protein Drugs Using Zwitterion-Functionalized Nanoparticles to Overcome both the Diffusion and Absorption Barriers

(2016) Wei Shan et al.   ACS Applied Materials & Interfaces

How to design the surface of peptide-loaded nanoparticles for efficient oral bioavailability?

(2016) Hélène Malhaire et al.   ADVANCED DRUG DELIVERY REVIEWS

Polymeric Nanoparticles Amenable to Simultaneous Installation of Exterior Targeting and Interior Therapeutic Proteins

(2016) Xi Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient mucus permeation and tight junction opening by dissociable “mucus-inert” agent coated trimethyl chitosan nanoparticles for oral insulin delivery

(2016) Min Liu et al.   JOURNAL OF CONTROLLED RELEASE

Core–shell stability of nanoparticles plays an important role for overcoming the intestinal mucus and epithelium barrier

(2016) Min Liu et al.   Journal of Materials Chemistry B

Overcoming the Diffusion Barrier of Mucus and Absorption Barrier of Epithelium by Self-Assembled Nanoparticles for Oral Delivery of Insulin

(2015) Wei Shan et al.   ACS Nano

Self-assembling bubble carriers for oral protein delivery

(2015) Er-Yuan Chuang et al.   BIOMATERIALS

A novel ligand conjugated nanoparticles for oral insulin delivery

(2015) Chong Liu et al.   DRUG DELIVERY

Enhancing Glioblastoma-Specific Penetration by Functionalization of Nanoparticles with an Iron-Mimic Peptide Targeting Transferrin/Transferrin Receptor Complex

(2015) Ting Kang et al.   MOLECULAR PHARMACEUTICS

Developments of mucus penetrating nanoparticles

(2015) Min Liu et al.   Asian Journal of Pharmaceutical Sciences

Mechanism Study of Cellular Uptake and Tight Junction Opening Mediated by Goblet Cell-Specific Trimethyl Chitosan Nanoparticles

(2014) Jian Zhang et al.   MOLECULAR PHARMACEUTICS

Targeted nanoparticles with novel non-peptidic ligands for oral delivery

(2013) Anne des Rieux et al.   ADVANCED DRUG DELIVERY REVIEWS

Intestinal mucosa permeability following oral insulin delivery using core shell corona nanolipoparticles

(2013) Xiuying Li et al.   BIOMATERIALS

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

(2013) Anna Salvati et al.   Nature Nanotechnology

Elucidating the signaling mechanism of an epithelial tight-junction opening induced by chitosan

(2012) Li-Wen Hsu et al.   BIOMATERIALS

Effects of pH on molecular mechanisms of chitosan–integrin interactions and resulting tight-junction disruptions

(2012) Li-Wen Hsu et al.   BIOMATERIALS

Transferrin receptor specific nanocarriers conjugated with functional 7peptide for oral drug delivery

(2012) Wenwen Du et al.   BIOMATERIALS

Calcium depletion-mediated protease inhibition and apical-junctional-complex disassembly via an EGTA-conjugated carrier for oral insulin delivery

(2012) Er-Yuan Chuang et al.   JOURNAL OF CONTROLLED RELEASE

Opening of Epithelial Tight Junctions and Enhancement of Paracellular Permeation by Chitosan: Microscopic, Ultrastructural, and Computed-Tomographic Observations

(2012) Kiran Sonaje et al.   MOLECULAR PHARMACEUTICS

A review of the prospects for polymeric nanoparticle platforms in oral insulin delivery

(2011) Mei-Chin Chen et al.   BIOMATERIALS

Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport

(2011) Yun Jin et al.   BIOMATERIALS

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma

(2010) Fernanda I. Staquicini et al.   JOURNAL OF CLINICAL INVESTIGATION

The characteristics, cellular uptake and intracellular trafficking of nanoparticles made of hydrophobically-modified chitosan

(2010) Ya-Ling Chiu et al.   JOURNAL OF CONTROLLED RELEASE

Preparation and evaluation of anti-neuroexcitation peptide (ANEP) loaded N-trimethyl chitosan chloride nanoparticles for brain-targeting

(2009) Siling Wang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The effect of surface functionality on cellular trafficking of dendrimers

(2008) Omathanu P. Perumal et al.   BIOMATERIALS