Enabling online determination of the size-dependent RNA content of lipid nanoparticle-based RNA formulations

Evolution of antibody immunity to SARS-CoV-2

(2021) Christian Gaebler et al.   NATURE

Nanomaterial Delivery Systems for mRNA Vaccines

(2021) Michael D. Buschmann et al.   Vaccines

Improved multidetector asymmetrical-flow field-flow fractionation method for particle sizing and concentration measurements of lipid-based nanocarriers for RNA delivery

(2021) R. Mildner et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The Effect of Size and Charge of Lipid Nanoparticles Prepared by Microfluidic Mixing on Their Lymph Node Transitivity and Distribution

(2020) Takashi Nakamura et al.   MOLECULAR PHARMACEUTICS

Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice

(2020) Paul F. McKay et al.   Nature Communications

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial

(2020) Maheshi N Ramasamy et al.   LANCET

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

(2020) Fernando P. Polack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nucleic Acid-Based Technologies Targeting Coronaviruses

(2020) Thi Khanh Le et al.   TRENDS IN BIOCHEMICAL SCIENCES

Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer

(2019) Alexandros Papachristofilou et al.   Journal for ImmunoTherapy of Cancer

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

(2019) Alexandra C. Walls et al.   CELL

Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA

(2019) Anna K. Blakney et al.   GENE THERAPY

Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies

(2018) Norbert Pardi et al.   Nature Communications

Characterising protein/detergent complexes by triple-detection size-exclusion chromatography

(2016) Katharina Gimpl et al.   BIOLOGICAL PROCEDURES ONLINE

Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety

(2016) Satoshi Uchida et al.   BIOMATERIALS

Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA

(2016) Sam Chen et al.   JOURNAL OF CONTROLLED RELEASE

Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy

(2016) Matthias A. Oberli et al.   NANO LETTERS

Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, andToxoplasma gondiichallenges with a single dose

(2016) Jasdave S. Chahal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Macromolecular Structure Evolution in Self-Assembled Lipid Nanoparticles for siRNA Delivery

(2014) Marian E. Gindy et al.   LANGMUIR

Stabilization of Ostwald Ripening in Low Molecular Weight Amino Lipid Nanoparticles for Systemic Delivery of siRNA Therapeutics

(2014) Marian E. Gindy et al.   MOLECULAR PHARMACEUTICS

A novel, disruptive vaccination technology

(2013) Karl-Josef Kallen et al.   Human Vaccines & Immunotherapeutics

Polydispersity Characterization of Lipid Nanoparticles for siRNA Delivery Using Multiple Detection Size-Exclusion Chromatography

(2012) Jingtao Zhang et al.   ANALYTICAL CHEMISTRY

Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core

(2012) Alex K. K. Leung et al.   Journal of Physical Chemistry C

Assessing the Heterogeneity Level in Lipid Nanoparticles for siRNA Delivery: Size-Based Separation, Compositional Heterogeneity, and Impact on Bioperformance

(2012) Jingtao Zhang et al.   MOLECULAR PHARMACEUTICS

Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection

(2012) Benjamin Petsch et al.   NATURE BIOTECHNOLOGY

Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

(2012) Nathan M Belliveau et al.   Molecular Therapy-Nucleic Acids

Variations in the optical properties of a particle suspension associated with viral infection of marine bacteria

(2010) Julia Uitz et al.   LIMNOLOGY AND OCEANOGRAPHY

A simple and general method for determining the protein and nucleic acid content of viruses by UV absorbance

(2010) J. Zachary Porterfield et al.   VIROLOGY