Icariin accelerates cartilage defect repair by promoting chondrogenic differentiation of BMSCs under conditions of oxygen‐glucose deprivation

Icariin prevents oestrogen deficiency–induced alveolar bone loss through promoting osteogenesis via STAT3

(2020) Hongyuan Xu et al.   CELL PROLIFERATION

Human dental pulp stem cells exhibit enhanced properties in comparison to human bone marrow stem cells on neurites outgrowth

(2020) Pierfrancesco Pagella et al.   FASEB JOURNAL

Icariin Alleviates Glucocorticoid-Induced Osteoporosis through EphB4/Ephrin-B2 Axis

(2020) Mi Huang et al.   Evidence-based Complementary and Alternative Medicine

Bone marrow mesenchymal stem cells improve bone erosion in collagen-induced arthritis by inhibiting osteoclasia-related factors and differentiating into chondrocytes

(2020) Jinfang Gao et al.   Stem Cell Research & Therapy

Cartilage tissue and therapeutic strategies for cartilage repair

(2020) Sahar Khajeh et al.   CURRENT MOLECULAR MEDICINE

Matrix-Induced Autologous Chondrocyte Implantation (MACI) Grafting for Osteochondral Lesions of the Talus

(2020) Christopher G. Lenz et al.   FOOT & ANKLE INTERNATIONAL

Icariin protects rabbit BMSCs against OGD-induced apoptosis by inhibiting ERs-mediated autophagy via MAPK signaling pathway

(2020) Donghua Liu et al.   LIFE SCIENCES

LncRNA H19 Regulates BMP2-Induced Hypertrophic Differentiation of Mesenchymal Stem Cells by Promoting Runx2 Phosphorylation

(2020) Guangming Dai et al.   Frontiers in Cell and Developmental Biology

Functionalization of Silk Fibroin Electrospun Scaffolds via BMSC Affinity Peptide Grafting through Oxidative Self-Polymerization of Dopamine for Bone Regeneration

(2019) Jiannan Wu et al.   ACS Applied Materials & Interfaces

Conditioned medium of mesenchymal stem cells delays osteoarthritis progression in a rat model by protecting subchondral bone, maintaining matrix homeostasis, and enhancing autophagy

(2019) Wenbo Chen et al.   Journal of Tissue Engineering and Regenerative Medicine

Excessive mechanical stress induces chondrocyte apoptosis through TRPV4 in an anterior cruciate ligament-transected rat osteoarthritis model

(2019) Bo Xu et al.   LIFE SCIENCES

Icariin alleviates osteoarthritis by inhibiting NLRP3-mediated pyroptosis

(2019) Yan Zu et al.   Journal of Orthopaedic Surgery and Research

SUMO‐modified bone marrow mesenchymal stem cells promoted the repair of articular cartilage in rats

(2019) Ying Liu et al.   CELL BIOLOGY INTERNATIONAL

Thermoresponsive Hyalomer intra-articular hydrogels improve monoiodoacetate-induced osteoarthritis in rats

(2019) Amira Sayed Hanafy et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Articular cartilage regeneration: the role of endogenous mesenchymal stem/progenitor cell recruitment and migration

(2019) Shuo Zhang et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Icariin Alleviates IL-1β-Induced Matrix Degradation By Activating The Nrf2/ARE Pathway In Human Chondrocytes

(2019) Shi Zuo et al.   Drug Design Development and Therapy

BMSCs-assisted injectable Col I hydrogel-regenerated cartilage defect by reconstructing superficial and calcified cartilage

(2019) Hanxu Cai et al.   Regenerative Biomaterials

A biphasic visco-hyperelastic damage model for articular cartilage: application to micromechanical modelling of the osteoarthritis-induced degradation behaviour

(2019) Dongxu Liu et al.   Biomechanics and Modeling in Mechanobiology

Anterior cruciate ligament transection of rabbits alters composition, structure and biomechanics of articular cartilage and chondrocyte deformation 2 weeks post-surgery in a site-specific manner

(2019) Simo P. Ojanen et al.   JOURNAL OF BIOMECHANICS

Icariin increases chondrocyte vitality by promoting hypoxia-inducible factor-1α expression and anaerobic glycolysis

(2019) Pengzhen Wang et al.   KNEE

Progress in Articular Cartilage Tissue Engineering: A Review on Therapeutic Cells and Macromolecular Scaffolds

(2019) Zhongyi Zhao et al.   MACROMOLECULAR BIOSCIENCE

Icariin abrogates osteoclast formation through the regulation of the RANKL-mediated TRAF6/NF-κB/ERK signaling pathway in Raw264.7 cells.

(2018) Buyun Kim et al.   PHYTOMEDICINE

Icariin Reduces Cartilage Degeneration in a Mouse Model of Osteoarthritis and is Associated with the Changes in Expression of Indian Hedgehog and Parathyroid Hormone-Related Protein

(2018) Yuan Luo et al.   MEDICAL SCIENCE MONITOR

Halofuginone attenuates articular cartilage degeneration by inhibition of elevated TGF-β1 signaling in articular cartilage in a rodent osteoarthritis model

(2017) Wenbo Mu et al.   Molecular Medicine Reports

Chondromodulin-I expression and correlation with angiogenesis in human osteoarthritic cartilage

(2017) Bing Deng et al.   Molecular Medicine Reports

Trophic Effects of Mesenchymal Stem Cells in Tissue Regeneration

(2017) Yao Fu et al.   TISSUE ENGINEERING PART B-REVIEWS

Dysregulation of the miR-146a-Smad4 axis impairs osteogenesis of bone mesenchymal stem cells under inflammation

(2017) Wei Kuang et al.   Bone Research

Hif-1α Overexpression Improves Transplanted Bone Mesenchymal Stem Cells Survival in Rat MCAO Stroke Model

(2017) Bingke Lv et al.   Frontiers in Molecular Neuroscience

Chm-1 gene-modified bone marrow mesenchymal stem cells maintain the chondrogenic phenotype of tissue-engineered cartilage

(2016) Zhuoyue Chen et al.   Stem Cell Research & Therapy

Cartilage Derived from Bone Marrow Mesenchymal Stem Cells Expresses Lubricin In Vitro and In Vivo

(2016) Yusuke Nakagawa et al.   PLoS One

Icariin enhances neuronal survival after oxygen and glucose deprivation by increasing SIRT1

(2009) Lin Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Engineering scaffold-free bone tissue using bone marrow stromal cell sheets

(2009) Dongyang Ma et al.   JOURNAL OF ORTHOPAEDIC RESEARCH