Cartilage Derived from Bone Marrow Mesenchymal Stem Cells Expresses Lubricin In Vitro and In Vivo

Treatment with recombinant lubricin attenuates osteoarthritis by positive feedback loop between articular cartilage and subchondral bone in ovariectomized rats

(2015) Zhuang Cui et al.   BONE

Arthroscopic Transplantation of Synovial Stem Cells Improves Clinical Outcomes in Knees With Cartilage Defects

(2015) Ichiro Sekiya et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Synovial mesenchymal stem cells promote healing after meniscal repair in microminipigs

(2015) Y. Nakagawa et al.   OSTEOARTHRITIS AND CARTILAGE

Mechanical motion promotes expression of Prg4 in articular cartilage via multiple CREB-dependent, fluid flow shear stress-induced signaling pathways

(2014) H. Ogawa et al.   GENES & DEVELOPMENT

Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo

(2014) Koji Otabe et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Physical activity ameliorates cartilage degeneration in a rat model of aging: A study on lubricin expression

(2014) G. Musumeci et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Transplantation of aggregates of synovial mesenchymal stem cells regenerates meniscus more effectively in a rat massive meniscal defect

(2013) Hiroki Katagiri et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Extra-virgin olive oil diet and mild physical activity prevent cartilage degeneration in an osteoarthritis model: an in vivo and in vitro study on lubricin expression

(2013) Giuseppe Musumeci et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Subchondral chitosan/blood implant-guided bone plate resorption and woven bone repair is coupled to hyaline cartilage regeneration from microdrill holes in aged rabbit knees

(2013) J. Guzmán-Morales et al.   OSTEOARTHRITIS AND CARTILAGE

The effects of physical activity on apoptosis and lubricin expression in articular cartilage in rats with glucocorticoid-induced osteoporosis

(2012) Giuseppe Musumeci et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Induction of superficial zone protein (SZP)/lubricin/PRG 4 in muscle-derived mesenchymal stem/progenitor cells by transforming growth factor-β1 and bone morphogenetic protein-7

(2012) José A Andrades et al.   ARTHRITIS RESEARCH & THERAPY

Properties and usefulness of aggregates of synovial mesenchymal stem cells as a source for cartilage regeneration

(2012) Shiro Suzuki et al.   ARTHRITIS RESEARCH & THERAPY

Cyclic loading increases friction and changes cartilage surface integrity in lubricin-mutant mouse knees

(2011) Elizabeth I. Drewniak et al.   ARTHRITIS AND RHEUMATISM

Mesenchymal stem cells from adipose tissue which have been differentiated into chondrocytes in three-dimensional culture express lubricin

(2011) Giuseppe Musumeci et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Human mesenchymal stem cells in synovial fluid increase in the knee with degenerated cartilage and osteoarthritis

(2011) Ichiro Sekiya et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Effects of Supplemental Intra-articular Lubricin and Hyaluronic Acid on the Progression of Posttraumatic Arthritis in the Anterior Cruciate Ligament–Deficient Rat Knee

(2010) Erin Teeple et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Loss of cartilage structure, stiffness, and frictional properties in mice lacking PRG4

(2010) Jeffrey M. Coles et al.   ARTHRITIS AND RHEUMATISM

Prevention of cartilage degeneration and restoration of chondroprotection by lubricin tribosupplementation in the rat following anterior cruciate ligament transection

(2010) Gregory D. Jay et al.   ARTHRITIS AND RHEUMATISM

Intraarticular Treatments for Osteoarthritis: New Perspectives

(2010) Xavier Chevalier   CURRENT DRUG TARGETS

Lubricin: a novel potential biotherapeutic approaches for the treatment of osteoarthritis

(2010) Jia-peng Bao et al.   MOLECULAR BIOLOGY REPORTS

Prevention of cartilage degeneration in a rat model of osteoarthritis by intraarticular treatment with recombinant lubricin

(2009) Carl R. Flannery et al.   ARTHRITIS AND RHEUMATISM

Morphological differences during in vitro chondrogenesis of bone marrow-, synovium-MSCs, and chondrocytes

(2009) Shizuko Ichinose et al.   LABORATORY INVESTIGATION

Mesenchymal Progenitor Cells Derived from Synovium and Infrapatellar Fat Pad as a Source for Superficial Zone Cartilage Tissue Engineering: Analysis of Superficial Zone Protein/Lubricin Expression

(2009) Sang Yang Lee et al.   TISSUE ENGINEERING PART A

Developments in the scientific understanding of osteoarthritis

(2009) Steven B Abramson et al.   ARTHRITIS RESEARCH & THERAPY

Decreased lubricin concentrations and markers of joint inflammation in the synovial fluid of patients with anterior cruciate ligament injury

(2008) K. A. Elsaid et al.   ARTHRITIS AND RHEUMATISM

Comparison of mesenchymal tissues-derived stem cells for in vivo chondrogenesis: suitable conditions for cell therapy of cartilage defects in rabbit

(2008) Hideyuki Koga et al.   CELL AND TISSUE RESEARCH

Mesenchymal stem cells derived from synovium, meniscus, anterior cruciate ligament, and articular chondrocytes share similar gene expression profiles

(2008) Yuko Segawa et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Coefficients of friction, lubricin, and cartilage damage in the anterior cruciate ligament-deficient guinea pig knee

(2007) Erin Teeple et al.   JOURNAL OF ORTHOPAEDIC RESEARCH