Icariin prevents oestrogen deficiency–induced alveolar bone loss through promoting osteogenesis via STAT3

Osteoporotic Changes in the Periodontium Impair Alveolar Bone Healing

(2019) M. Arioka et al.   JOURNAL OF DENTAL RESEARCH

Icariin Restores Bone Structure and Strength in a Rat Model of Chronic High-Dose Alcohol-Induced Osteopenia

(2018) Jie-Zhou Wu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The Specific Morphological Features of Alveolar Bone

(2018) Siru Zhou et al.   JOURNAL OF CRANIOFACIAL SURGERY

Natural Estrogen Receptor Modulators and Their Heterologous Biosynthesis

(2018) Jiali Yang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Osteoporosis treatment: recent developments and ongoing challenges

(2017) Sundeep Khosla et al.   Lancet Diabetes & Endocrinology

Evaluation of Osteogenesis and Angiogenesis of Icariin in Local Controlled Release and Systemic Delivery for Calvarial Defect in Ovariectomized Rats

(2017) Yuqiong Wu et al.   Scientific Reports

Icariin promotes osteogenic differentiation of rat bone marrow stromal cells by activating the ERα-Wnt/β-catenin signaling pathway

(2016) QiuShi Wei et al.   BIOMEDICINE & PHARMACOTHERAPY

Use of Plant-Based Therapies and Menopausal Symptoms

(2016) Oscar H. Franco et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Osteoprotective Effects of Estrogen in the Maxillary Bone Depend on ERα

(2016) S. Macari et al.   JOURNAL OF DENTAL RESEARCH

Vitamin D Status and Tooth Loss in Postmenopausal Females: The Buffalo Osteoporosis and Periodontal Disease (OsteoPerio) Study

(2016) Sonja Pavlesen et al.   JOURNAL OF PERIODONTOLOGY

Postmenopausal Osteoporosis

(2016) Dennis M. Black et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mediator MED23 cooperates with RUNX2 to drive osteoblast differentiation and bone development

(2016) Zhen Liu et al.   Nature Communications

Osteoporosis and Periodontitis

(2016) Chin-Wei Wang et al.   Current Osteoporosis Reports

Postmenopausal osteoporosis

(2016) Richard Eastell et al.   Nature Reviews Disease Primers

Icariin induces osteogenic differentiation of bone mesenchymal stem cells in a MAPK-dependent manner

(2015) Yuqiong Wu et al.   CELL PROLIFERATION

Patterns and predictors of osteoporosis medication discontinuation and switching among Medicare beneficiaries

(2014) Huifeng Yun et al.   BMC MUSCULOSKELETAL DISORDERS

Therapeutic modulators of STAT signalling for human diseases

(2013) Gabriella Miklossy et al.   NATURE REVIEWS DRUG DISCOVERY

Ovariectomy induces osteoporosis in the maxillary alveolar bone: anin vivomicro-CT and histomorphometric analysis in rats

(2013) Q-G Dai et al.   ORAL DISEASES

Icariin promotes bone formation via the BMP-2/Smad4 signal transduction pathway in the hFOB 1.19 human osteoblastic cell line

(2012) WENNA LIANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling

(2012) Lei-Guo Ming et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Osteoblast/osteocyte-specific inactivation of Stat3 decreases load-driven bone formation and accumulates reactive oxygen species

(2011) Hongkang Zhou et al.   BONE

Icariin protects against bone loss induced by oestrogen deficiency and activates oestrogen receptor-dependent osteoblastic functions in UMR 106 cells

(2010) Sao-Keng Mok et al.   BRITISH JOURNAL OF PHARMACOLOGY

Icariin is more potent than genistein in promoting osteoblast differentiation and mineralization in vitro

(2010) Hui-Ping Ma et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Gene for Aromatase, a Rate-Limiting Enzyme for Local Estrogen Biosynthesis, Is a Downstream Target Gene of Runx2 in Skeletal Tissues

(2010) J. H. Jeong et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy

(2008) R. G. G. Russell et al.   OSTEOPOROSIS INTERNATIONAL

Effects of total flavonoids and flavonol glycosides from Epimedium koreanum Nakai on the proliferation and differentiation of primary osteoblasts

(2007) D.-W. Zhang et al.   PHYTOMEDICINE