Antibodies binding diverse pertactin epitopes protect mice from B. pertussis infection

Broadly Reactive Human Monoclonal Antibodies Targeting the Pneumococcal Histidine Triad Protein Protect against Fatal Pneumococcal Infection

(2021) Jiachen Huang et al.   INFECTION AND IMMUNITY

Structural basis for antibody binding to adenylate cyclase toxin reveals RTX linkers as neutralization-sensitive epitopes

(2021) Jory A. Goldsmith et al.   PLoS Pathogens

Neutralization of pertussis toxin by a single antibody prevents clinical pertussis in neonatal baboons

(2020) Annalee W. Nguyen et al.   Science Advances

Development and Standardization of a High-Throughput Bordetella pertussis Growth-Inhibition Assay

(2020) Anaïs Thiriard et al.   Frontiers in Microbiology

Acellular Pertussis Vaccines Induce Anti-pertactin Bactericidal Antibodies Which Drives the Emergence of Pertactin-Negative Strains

(2020) Elodie Lesne et al.   Frontiers in Microbiology

Pertactin-deficient Bordetella pertussis isolates: evidence of increased circulation in Europe, 1998 to 2015

(2019) Alex-Mikael Barkoff et al.   Eurosurveillance

Evaluation of adenylate cyclase toxoid antigen in acellular pertussis vaccines using a Bordetella pertussis challenge model in mice.

(2018) Dylan T. Boehm et al.   INFECTION AND IMMUNITY

Antigenic Variation in Streptococcus pneumoniae PspC Promotes Immune Escape in the Presence of Variant-Specific Immunity

(2018) M. Georgieva et al.   mBio

Bordetella pertussis pertactin knock-out strains reveal immunomodulatory properties of this virulence factor

(2018) Elise Sofie Hovingh et al.   Emerging Microbes & Infections

Bordetella pertussis isolates vary in their interactions with human complement components

(2018) Charlotte Brookes et al.   Emerging Microbes & Infections

Emerging Bordetella pertussis Strains Induce Enhanced Signaling of Human Pattern Recognition Receptors TLR2, NOD2 and Secretion of IL-10 by Dendritic Cells

(2017) Elise S. Hovingh et al.   PLoS One

Highly reduced binding to high and low affinity mouse Fc gamma receptors by L234A/L235A and N297A Fc mutations engineered into mouse IgG2a

(2015) E. Arduin et al.   MOLECULAR IMMUNOLOGY

A cocktail of humanized anti–pertussis toxin antibodies limits disease in murine and baboon models of whooping cough

(2015) Annalee W. Nguyen et al.   Science Translational Medicine

Prefusion F–specific antibodies determine the magnitude of RSV neutralizing activity in human sera

(2015) Joan O. Ngwuta et al.   Science Translational Medicine

Pertactin-Negative Bordetella pertussis Strains: Evidence for a Possible Selective Advantage

(2014) S. W. Martin et al.   CLINICAL INFECTIOUS DISEASES

Prevalence and Molecular Characterization of Pertactin-Deficient Bordetella pertussis in the United States

(2013) L. C. Pawloski et al.   Clinical and Vaccine Immunology

Complex Correlates of Protection After Vaccination

(2013) S. A. Plotkin   CLINICAL INFECTIOUS DISEASES

Prevalence and Genetic Characterization of Pertactin-Deficient Bordetella pertussis in Japan

(2012) Nao Otsuka et al.   PLoS One

Immunization of Teenagers with a Fifth Dose of Reduced DTaP-IPV Induces High Levels of Pertussis Antibodies with a Significant Increase in Opsonophagocytic Activity

(2011) Audun Aase et al.   Clinical and Vaccine Immunology

Studies on Prn Variation in the Mouse Model and Comparison with Epidemiological Data

(2011) Marjolein van Gent et al.   PLoS One

Oligosaccharide conjugates of Bordetella pertussis and bronchiseptica induce bactericidal antibodies, an addition to pertussis vaccine

(2011) J. Kubler-Kielb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pertactin Is Required for Bordetella Species To Resist Neutrophil-Mediated Clearance

(2010) C. S. Inatsuka et al.   INFECTION AND IMMUNITY

Elongated fibrillar structure of a streptococcal adhesin assembled by the high-affinity association of  - and PPII-helices

(2010) M. R. Larson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA