Complex Correlates of Protection After Vaccination

Relationship between haemagglutination-inhibiting antibody titres and clinical protection against influenza: development and application of a bayesian random-effects model

(2012) Laurent Coudeville et al.   BMC Medical Research Methodology

Preliminary Assessment of the Efficacy of a T-Cell–Based Influenza Vaccine, MVA-NP+M1, in Humans

(2012) Patrick J. Lillie et al.   CLINICAL INFECTIOUS DISEASES

Nomenclature for Immune Correlates of Protection After Vaccination

(2012) S. A. Plotkin et al.   CLINICAL INFECTIOUS DISEASES

Unexpectedly Limited Durability of Immunity Following Acellular Pertussis Vaccination in Preadolescents in a North American Outbreak

(2012) Maxwell A. Witt et al.   CLINICAL INFECTIOUS DISEASES

Antibodies Against Neutralization Epitopes of Human Cytomegalovirus gH/gL/pUL128-130-131 Complex and Virus Spreading May Correlate with Virus Control In Vivo

(2012) Daniele Lilleri et al.   JOURNAL OF CLINICAL IMMUNOLOGY

T-Helper 1 Cells Elicited by H5N1 Vaccination Predict Seroprotection

(2012) Gabriel K. Pedersen et al.   JOURNAL OF INFECTIOUS DISEASES

Antiviral Inhibitory Capacity of CD8+ T cells Predicts the Rate of CD4+ T-Cell Decline in HIV-1 Infection

(2012) Hongbing Yang et al.   JOURNAL OF INFECTIOUS DISEASES

Gene-Based Vaccination with a Mismatched Envelope Protects against Simian Immunodeficiency Virus Infection in Nonhuman Primates

(2012) L. Flatz et al.   JOURNAL OF VIROLOGY

Antibody-Dependent Cellular Cytotoxicity against Primary HIV-Infected CD4+T Cells Is Directly Associated with the Magnitude of Surface IgG Binding

(2012) Adjoa Smalls-Mantey et al.   JOURNAL OF VIROLOGY

Gag-Specific Cellular Immunity DeterminesIn VitroViral Inhibition andIn VivoVirologic Control following Simian Immunodeficiency Virus Challenges of Vaccinated Rhesus Monkeys

(2012) Kathryn E. Stephenson et al.   JOURNAL OF VIROLOGY

Initial HIV-1 Antigen-Specific CD8+ T Cells in Acute HIV-1 Infection Inhibit Transmitted/Founder Virus Replication

(2012) S. A. Freel et al.   JOURNAL OF VIROLOGY

The Contribution of Systemic and Pulmonary Immune Effectors to Vaccine-Induced Protection from H5N1 Influenza Virus Infection

(2012) Y.-F. Lau et al.   JOURNAL OF VIROLOGY

Antibodies against the gH/gL/UL128/UL130/UL131 Complex Comprise the Majority of the Anti-Cytomegalovirus (Anti-CMV) Neutralizing Antibody Response in CMV Hyperimmune Globulin

(2012) A. E. Fouts et al.   JOURNAL OF VIROLOGY

Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies from an HIV-1 Vaccine Efficacy Trial Target Multiple Epitopes and Preferentially Use the VH1 Gene Family

(2012) M. Bonsignori et al.   JOURNAL OF VIROLOGY

Passively Transmitted gp41 Antibodies in Babies Born from HIV-1 Subtype C-Seropositive Women: Correlation between Fine Specificity and Protection

(2012) L. Diomede et al.   JOURNAL OF VIROLOGY

A novel therapeutic cytomegalovirus DNA vaccine in allogeneic haemopoietic stem-cell transplantation: a randomised, double-blind, placebo-controlled, phase 2 trial

(2012) Mohamed A Kharfan-Dabaja et al.   LANCET INFECTIOUS DISEASES

Burden of disease associated with human cytomegalovirus and prospects for elimination by universal immunisation

(2012) Paul D Griffiths   LANCET INFECTIOUS DISEASES

Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2

(2012) Morgane Rolland et al.   NATURE

Vaccine-induced CD8+ T cells control AIDS virus replication

(2012) Philip A. Mudd et al.   NATURE

Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

(2012) Dan H. Barouch et al.   NATURE

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

(2012) Tom M Wilkinson et al.   NATURE MEDICINE

Waning Protection after Fifth Dose of Acellular Pertussis Vaccine in Children

(2012) Nicola P. Klein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

(2012) Barton F. Haynes et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Worldwide Impact of the Seven-valent Pneumococcal Conjugate Vaccine

(2012) Sean P. Fitzwater et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Why Do Pertussis Vaccines Fail?

(2012) J. D. Cherry   PEDIATRICS

Protective Efficacy of Neutralizing Monoclonal Antibodies in a Nonhuman Primate Model of Ebola Hemorrhagic Fever

(2012) Andrea Marzi et al.   PLoS One

Monitoring of Human Cytomegalovirus and Virus-Specific T-Cell Response in Young Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation

(2012) Daniele Lilleri et al.   PLoS One

MHC Class I-Presented T Cell Epitopes Identified by Immunoproteomics Analysis Are Targets for a Cross Reactive Influenza-Specific T Cell Response

(2012) James S. Testa et al.   PLoS One

Successful Treatment of Ebola Virus-Infected Cynomolgus Macaques with Monoclonal Antibodies

(2012) X. Qiu et al.   Science Translational Medicine

Differences in avidity of IgG antibodies to pertussis toxin after acellular pertussis booster vaccination and natural infection

(2012) Alex-Mikael Barkoff et al.   VACCINE

The role of nasal IgA in children vaccinated with live attenuated influenza vaccine

(2012) Christopher S. Ambrose et al.   VACCINE

Ebolavirus vaccines for humans and apes

(2012) Hugues Fausther-Bovendo et al.   Current Opinion in Virology

Rotavirus immune responses and correlates of protection

(2012) Juana Angel et al.   Current Opinion in Virology

Adjuvanted influenza vaccines

(2012) Nicola Principi et al.   Human Vaccines & Immunotherapeutics

Critical Role of Perforin-dependent CD8+ T Cell Immunity for Rapid Protective Vaccination in a Murine Model for Human Smallpox

(2012) Melanie Kremer et al.   PLoS Pathogens

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Correlation between levels of human papillomavirus (HPV)-16 and 18 antibodies in serum and cervicovaginal secretions in girls and women vaccinated with the HPV-16/18 AS04-adjuvanted vaccine

(2011) Tino F. Schwarz et al.   Human vaccines & immunotherapeutics

Immune correlates of protection against influenza: challenges for licensure of seasonal and pandemic influenza vaccines, Miami, FL, USA, March 1-3, 2010

(2011) Lars R. Haaheim et al.   Influenza and Other Respiratory Viruses

Influenza Hemagglutination-Inhibition Antibody Titer as a Correlate of Vaccine-Induced Protection

(2011) Suzanne E. Ohmit et al.   JOURNAL OF INFECTIOUS DISEASES

Live and Inactivated Influenza Vaccines Induce Similar Humoral Responses, but Only Live Vaccines Induce Diverse T-Cell Responses in Young Children

(2011) Daniel F. Hoft et al.   JOURNAL OF INFECTIOUS DISEASES

Efficacy, safety, and immunogenicity of a Vero-cell-culture-derived trivalent influenza vaccine: a multicentre, double-blind, randomised, placebo-controlled trial

(2011) P Noel Barrett et al.   LANCET

Phase Ia Clinical Evaluation of the Plasmodium falciparum Blood-stage Antigen MSP1 in ChAd63 and MVA Vaccine Vectors

(2011) Susanne H Sheehy et al.   MOLECULAR THERAPY

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

(2011) Scott G. Hansen et al.   NATURE

Immunological mechanisms of vaccination

(2011) Bali Pulendran et al.   NATURE IMMUNOLOGY

CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates

(2011) Nancy J Sullivan et al.   NATURE MEDICINE

First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Hemagglutination Inhibition Antibody Titers as a Correlate of Protection for Inactivated Influenza Vaccines in Children

(2011) Steven Black et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Protective Immunity Induced with the RTS,S/AS Vaccine Is Associated with IL-2 and TNF-α Producing Effector and Central Memory CD4+ T Cells

(2011) Joanne M. Lumsden et al.   PLoS One

Circumsporozoite-Specific T Cell Responses in Children Vaccinated with RTS,S/AS01E and Protection against P falciparum Clinical Malaria

(2011) Ally Olotu et al.   PLoS One

Oligosaccharide conjugates of Bordetella pertussis and bronchiseptica induce bactericidal antibodies, an addition to pertussis vaccine

(2011) J. Kubler-Kielb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccine induced antibodies to the first variable loop of human immunodeficiency virus type 1 gp120, mediate antibody-dependent virus inhibition in macaques

(2011) Izabela Bialuk et al.   VACCINE

Cellular immune response in the presence of protective antibody levels correlates with protection against 1918 influenza in ferrets

(2011) Stéphane Pillet et al.   VACCINE

Immune correlates of protection against yellow fever determined by passive immunization and challenge in the hamster model

(2011) Justin G. Julander et al.   VACCINE

Quantitative analysis of neutralizing antibody response to human cytomegalovirus in natural infection

(2011) Dai Wang et al.   VACCINE

Immune responses to influenza virus infection

(2011) J.H.C.M. Kreijtz et al.   VIRUS RESEARCH

Neutralizing Antibodies and Control of HIV: Moves and Countermoves

(2011) Ann J. Hessell et al.   Current HIV/AIDS Reports

Influenza vaccine responses in older adults

(2010) Janet E. McElhaney   AGEING RESEARCH REVIEWS

Correlates of Protection Induced by Vaccination

(2010) S. A. Plotkin   Clinical and Vaccine Immunology

Influenza A virus-specific CD8+T-cell responses: from induction to function

(2010) MR Olson et al.   Future Virology

Development of improved vaccines against whooping cough: Current status

(2010) Ibrahim Marzouqi et al.   Human vaccines & immunotherapeutics

Smallpox vaccines: targets of protective immunity

(2010) Bernard Moss   IMMUNOLOGICAL REVIEWS

Inflammasome Activation by Adenylate Cyclase Toxin Directs Th17 Responses and Protection against Bordetella pertussis

(2010) A. Dunne et al.   JOURNAL OF IMMUNOLOGY

Influence of Potential Protective Mechanisms on the Development of Live Rotavirus Vaccines

(2010) Richard L. Ward et al.   JOURNAL OF INFECTIOUS DISEASES

Expression of Genes Associated with Immunoproteasome Processing of Major Histocompatibility Complex Peptides Is Indicative of Protection with Adjuvanted RTS,S Malaria Vaccine

(2010) Maryanne T. Vahey et al.   JOURNAL OF INFECTIOUS DISEASES

Immune Responses to Rotavirus Infection and Vaccination and Associated Correlates of Protection

(2010) U. Desselberger et al.   JOURNAL OF INFECTIOUS DISEASES

T-Cell Correlates of Vaccine Efficacy after a Heterologous Simian Immunodeficiency Virus Challenge

(2010) M. A. Martins et al.   JOURNAL OF VIROLOGY

Antiviral Immunity following Smallpox Virus Infection: a Case-Control Study

(2010) E. Hammarlund et al.   JOURNAL OF VIROLOGY

Antibody-Mediated Protection against Mucosal Simian-Human Immunodeficiency Virus Challenge of Macaques Immunized with Alphavirus Replicon Particles and Boosted with Trimeric Envelope Glycoprotein in MF59 Adjuvant

(2010) S. W. Barnett et al.   JOURNAL OF VIROLOGY

Vaccine-Acquired Rotavirus in Infants with Severe Combined Immunodeficiency

(2010) Niraj C. Patel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Innate and adaptive immune correlates of vaccine and adjuvant-induced control of mucosal transmission of SIV in macaques

(2010) Y. Sui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses

(2010) M. J. P. Welters et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Key concepts in immunology

(2010) Muriel Moser et al.   VACCINE

Lung homing CTLs and their proliferation ability are important correlates of vaccine protection against influenza

(2010) Jianping Lin et al.   VACCINE

Prime-Boost Immunization with Adenoviral and Modified Vaccinia Virus Ankara Vectors Enhances the Durability and Polyfunctionality of Protective Malaria CD8+ T-Cell Responses

(2009) A. Reyes-Sandoval et al.   INFECTION AND IMMUNITY

Randomized, Double‐Blind, Phase 2a Trial of Falciparum Malaria Vaccines RTS,S/AS01B and RTS,S/AS02A in Malaria‐Naive Adults: Safety, Efficacy, and Immunologic Associates of Protection

(2009) Kent E. Kester et al.   JOURNAL OF INFECTIOUS DISEASES

Correlates of protective immunity for Ebola vaccines: implications for regulatory approval by the animal rule

(2009) Nancy J. Sullivan et al.   NATURE REVIEWS MICROBIOLOGY

Vaccine Prevention of Maternal Cytomegalovirus Infection

(2009) Robert F. Pass et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

PERTUSSIS OUTBREAK IN PRIMARY AND SECONDARY SCHOOLS IN LUDWIGSLUST, GERMANY DEMONSTRATING THE ROLE OF WANING IMMUNITY

(2009) Muna Abu Sin et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Insights into Long-Lasting Protection Induced by RTS,S/AS02A Malaria Vaccine: Further Results from a Phase IIb Trial in Mozambican Children

(2009) Caterina Guinovart et al.   PLoS One

Granzyme B: Correlates with protection and enhanced CTL response to influenza vaccination in older adults

(2009) Janet E. McElhaney et al.   VACCINE

Serum anti-toxin B antibody correlates with protection from recurrent Clostridium difficile infection (CDI)

(2009) Brett A. Leav et al.   VACCINE

The role of Toll-like receptor-4 in pertussis vaccine-induced immunity

(2008) Sander Banus et al.   BMC IMMUNOLOGY

Correlation of Cellular Immune Responses with Protection against Culture-Confirmed Influenza Virus in Young Children

(2008) B. D. Forrest et al.   Clinical and Vaccine Immunology

Vaccines: Correlates of Vaccine‐Induced Immunity

(2008) Stanley A. Plotkin   CLINICAL INFECTIOUS DISEASES

CD8+ T cell efficacy in vaccination and disease

(2008) Victor Appay et al.   NATURE MEDICINE

Immunogenicity and serotype-specific efficacy of a 9-valent pneumococcal conjugate vaccine (PCV-9) determined during an efficacy trial in The Gambia

(2008) M. Saaka et al.   VACCINE