SARS-CoV-2 Psychiatric Sequelae: A Review of Neuroendocrine Mechanisms and Therapeutic Strategies

THE IMPACT OF COVID-19 VIRAL INFECTION ON THE HYPOTHALAMIC PITUITARY ADRENAL AXIS

(2021) Ali S. Alzahrani et al.   Endocrine Practice

Glucocorticoids and the brain after critical illness

(2021) Alice R Hill et al.   ENDOCRINOLOGY

Pathophysiological Clues to How the Emergent SARS-CoV-2 Can Potentially Increase the Susceptibility to Neurodegeneration

(2021) Mahsa Dolatshahi et al.   MOLECULAR NEUROBIOLOGY

Neurological infection with SARS-CoV-2 — the story so far

(2021) Tom Solomon   Nature Reviews Neurology

The IL-6 antagonist tocilizumab is associated with worse depression and related symptoms in the medically ill

(2021) Jennifer M. Knight et al.   Translational Psychiatry

The Adrenal Cortex, an Underestimated Site of SARS-CoV-2 Infection

(2021) Yanfei Mao et al.   Frontiers in Endocrinology

Association between antidepressant use and reduced risk of intubation or death in hospitalized patients with COVID-19: results from an observational study

(2021) Nicolas Hoertel et al.   MOLECULAR PSYCHIATRY

How Does COVID-19 Affect the Neurobiology of Suicide?

(2021) I. Conejero et al.   Current Psychiatry Reports

Trial of Psilocybin versus Escitalopram for Depression

(2021) Robin Carhart-Harris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cardiovascular drugs and COVID‐19 clinical outcomes: A living systematic review and meta‐analysis

(2021) Innocent G. Asiimwe et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Immune Biomarkers Alterations in Post-traumatic Stress Disorder: A Systematic Review and Meta-analysis

(2020) Juan-Juan Yang et al.   JOURNAL OF AFFECTIVE DISORDERS

Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host–Virus Interaction, and Proposed Neurotropic Mechanisms

(2020) Abdul Mannan Baig et al.   ACS Chemical Neuroscience

COVID-19, ACE2, and the cardiovascular consequences

(2020) Andrew M. South et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Posttraumatic stress disorder and depression of survivors 12 months after the outbreak of Middle East respiratory syndrome in South Korea

(2020) Hye Yoon Park et al.   BMC PUBLIC HEALTH

Nervous system involvement after infection with COVID-19 and other coronaviruses

(2020) Yeshun Wu et al.   BRAIN BEHAVIOR AND IMMUNITY

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

An alteration of the dopamine synthetic pathway is possibly involved in the pathophysiology of COVID-19

(2020) Serge Nataf   JOURNAL OF MEDICAL VIROLOGY

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the neuroendocrine stress axis

(2020) Charlotte Steenblock et al.   MOLECULAR PSYCHIATRY

Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19

(2020) Muthiah Vaduganathan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Posttraumatic stress symptoms and attitude toward crisis mental health services among clinically stable patients with COVID-19 in China

(2020) Hai-Xin Bo et al.   PSYCHOLOGICAL MEDICINE

Melatonin: Roles in influenza, Covid‐19, and other viral infections

(2020) George Anderson et al.   REVIEWS IN MEDICAL VIROLOGY

Long-term alterations in brain and behavior after postnatal Zika virus infection in infant macaques

(2020) Jessica Raper et al.   Nature Communications

Psycho-Neuroendocrine-Immune Interactions in COVID-19: Potential Impacts on Mental Health

(2020) Ícaro Raony et al.   Frontiers in Immunology

Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection

(2020) Xin Zou et al.   Frontiers of Medicine

Massive transient damage of the olfactory epithelium associated with infection of sustentacular cells by SARS-CoV-2 in golden Syrian hamsters

(2020) Bertrand Bryche et al.   BRAIN BEHAVIOR AND IMMUNITY

SARS-CoV-2 infects and damages the mature and immature olfactory sensory neurons of hamsters

(2020) Anna Jinxia Zhang et al.   CLINICAL INFECTIOUS DISEASES

COVID-19: Drug Targets and Potential Treatments

(2020) Carmen Gil et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

Candidate drugs against SARS-CoV-2 and COVID-19

(2020) Dwight L. McKee et al.   PHARMACOLOGICAL RESEARCH

ACE2, Much More Than Just a Receptor for SARS-COV-2

(2020) Lobelia Samavati et al.   Frontiers in Cellular and Infection Microbiology

Case Report: Adrenal Pathology Findings in Severe COVID-19: An Autopsy Study

(2020) Monique Freire Santana et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Renin–angiotensin system inhibitors and the severity of coronavirus disease 2019 in Kanagawa, Japan: a retrospective cohort study

(2020) Yasushi Matsuzawa et al.   HYPERTENSION RESEARCH

Would ACEIs/ARBs be beneficial for COVID-19 patients without hypertension?

(2020) Ying Huang et al.   PHARMACOLOGICAL RESEARCH

Psychotic symptoms in COVID-19 patients. A retrospective descriptive study

(2020) A. Parra et al.   PSYCHIATRY RESEARCH

Histological Evidence for the Enteric Nervous System and the Choroid Plexus as Alternative Routes of Neuroinvasion by SARS-CoV2

(2020) Felix Deffner et al.   Frontiers in Neuroanatomy

Comparison of infection risks and clinical outcomes in patients with and without SARS‐CoV‐2 lung infection under renin–angiotensin–aldosterone system blockade: Systematic review and meta‐analysis

(2020) Chang Chu et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19

(2020) Eric J. Lenze et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The SARS-CoV-2 and mental health: From biological mechanisms to social consequences

(2020) Dorota Szcześniak et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Acute Cerebrovascular Events With COVID-19 Infection

(2020) Mandip S. Dhamoon et al.   STROKE

Repurposing of Biologic and Targeted Synthetic Anti-Rheumatic Drugs in COVID-19 and Hyper-Inflammation: A Comprehensive Review of Available and Emerging Evidence at the Peak of the Pandemic

(2020) Giulio Cavalli et al.   Frontiers in Pharmacology

Depression as a Mediator of Chronic Fatigue and Post-Traumatic Stress Symptoms in Middle East Respiratory Syndrome Survivors

(2019) So Hee Lee et al.   Psychiatry Investigation

The real world impact of adalimumab on quality of life and the physical and psychological effects of moderate-to-severe psoriasis: a UK prospective, multicenter, observational study

(2019) Joyce Leman et al.   JOURNAL OF DERMATOLOGICAL TREATMENT

The kynurenine pathway: a finger in every pie

(2019) Jonathan Savitz   MOLECULAR PSYCHIATRY

Psychosis as an adverse effect of monoclonal antibody immunotherapy

(2019) Norah Essali et al.   BRAIN BEHAVIOR AND IMMUNITY

Markers of central inflammation in major depressive disorder: A systematic review and meta-analysis of studies examining cerebrospinal fluid, positron emission tomography and post-mortem brain tissue

(2019) Daniela Enache et al.   BRAIN BEHAVIOR AND IMMUNITY

Ketamine and depression: a narrative review

(2019) Alexandrine Corriger et al.   Drug Design Development and Therapy

Zika Virus Infection — After the Pandemic

(2019) Didier Musso et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?

(2019) Marc Desforges et al.   Viruses-Basel

Depletion of angiotensin-converting enzyme 2 reduces brain serotonin and impairs the running-induced neurogenic response

(2018) Friederike Klempin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Post-Polio Syndrome and the Late Effects of Poliomyelitis: Part 2. Treatment, Management and Prognosis

(2018) Julian K. Lo et al.   MUSCLE & NERVE

Coupling corticotropin-releasing-hormone and angiotensin converting enzyme 2 dampens stress responsiveness in male mice

(2018) Lei A. Wang et al.   NEUROPHARMACOLOGY

Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms

(2018) Panos Zanos et al.   PHARMACOLOGICAL REVIEWS

Rapid inflammation modulation and antidepressant efficacy of a low-dose ketamine infusion in treatment-resistant depression: A randomized, double-blind control study

(2018) Mu-Hong Chen et al.   PSYCHIATRY RESEARCH

Protocol for the insight study: a randomised controlled trial of single-dose tocilizumab in patients with depression and low-grade inflammation

(2018) Golam M Khandaker et al.   BMJ Open

ACE2 in Brain Physiology and Pathophysiology: Evidence from Transgenic Animal Models

(2018) Natalia Alenina et al.   NEUROCHEMICAL RESEARCH

The Range of Neurological Complications in Chikungunya Fever

(2017) T. Cerny et al.   Neurocritical Care

Neuroendocrine and neurophysiological effects of interleukin 6 in rheumatoid arthritis

(2017) Ernest H S Choy et al.   RHEUMATOLOGY

Kynurenic Acid in Schizophrenia: A Systematic Review and Meta-analysis

(2017) Eric Plitman et al.   SCHIZOPHRENIA BULLETIN

Meta-analysis of Cerebrospinal Fluid Cytokine and Tryptophan Catabolite Alterations in Psychiatric Patients: Comparisons Between Schizophrenia, Bipolar Disorder, and Depression

(2017) Alexandre K Wang et al.   SCHIZOPHRENIA BULLETIN

Chronic administration of fluoxetine and pro-inflammatory cytokine change in a rat model of depression

(2017) Yanxia Lu et al.   PLoS One

Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation

(2016) Michael R. Irwin et al.   BIOLOGICAL PSYCHIATRY

Relationship between neurotoxic kynurenine metabolites and reductions in right medial prefrontal cortical thickness in major depressive disorder

(2016) Timothy B. Meier et al.   BRAIN BEHAVIOR AND IMMUNITY

The Effect of Dexamethasone on Symptoms of Posttraumatic Stress Disorder and Depression After Cardiac Surgery and Intensive Care Admission

(2016) Lotte Kok et al.   CRITICAL CARE MEDICINE

The association of renin-angiotensin system blockade use with the risks of cognitive impairment of aging and Alzheimer’s disease: A meta-analysis

(2016) Shan Zhuang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Association between Zika virus infection and microcephaly in Brazil, January to May, 2016: preliminary report of a case-control study

(2016) Thalia Velho Barreto de Araújo et al.   LANCET INFECTIOUS DISEASES

Antidepressant activity of anti-cytokine treatment: a systematic review and meta-analysis of clinical trials of chronic inflammatory conditions

(2016) N Kappelmann et al.   MOLECULAR PSYCHIATRY

Increasing brain angiotensin converting enzyme 2 activity decreases anxiety-like behavior in male mice by activating central Mas receptors

(2016) Lei Wang et al.   NEUROPHARMACOLOGY

Meta-Analysis of Cytokines and Chemokines in Suicidality: Distinguishing Suicidal Versus Nonsuicidal Patients

(2015) Carmen Black et al.   BIOLOGICAL PSYCHIATRY

Severe neurologic syndrome associated with Middle East respiratory syndrome corona virus (MERS-CoV)

(2015) Y. M. Arabi et al.   INFECTION

Clinical aspects and outcomes of 70 patients with Middle East respiratory syndrome coronavirus infection: a single-center experience in Saudi Arabia

(2014) Mustafa Saad et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Connecting inflammation with glutamate agonism in suicidality

(2013) Sophie Erhardt et al.   NEUROPSYCHOPHARMACOLOGY

The effect of TNF-alpha blockers on psychometric measures in ankylosing spondylitis patients: a preliminary observation

(2013) Ozden Arısoy et al.   RHEUMATOLOGY INTERNATIONAL

Increased Prevalence of Diverse N -Methyl-D-Aspartate Glutamate Receptor Antibodies in Patients With an Initial Diagnosis of Schizophrenia

(2013) Johann Steiner et al.   JAMA Psychiatry

Defective intestinal amino acid absorption in Ace2 null mice

(2012) Dustin Singer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Does Intraoperative Ketamine Attenuate Inflammatory Reactivity Following Surgery? A Systematic Review and Meta-Analysis

(2012) Ola Dale et al.   ANESTHESIA AND ANALGESIA

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

(2012) Tatsuo Hashimoto et al.   NATURE

Non-opioid IV adjuvants in the perioperative period: Pharmacological and clinical aspects of ketamine and gabapentinoids

(2012) Avi A. Weinbroum   PHARMACOLOGICAL RESEARCH

Glucocorticoid-endocannabinoid interaction in cardiac surgical patients: relationship to early cognitive dysfunction and late depression

(2012) Daniela Hauer et al.   REVIEWS IN THE NEUROSCIENCES

Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study

(2011) Harvey Moldofsky et al.   BMC Neurology

Effects of telmisartan on cognition and regional cerebral blood flow in hypertensive patients with Alzheimer's disease

(2011) Kazumasa Kume et al.   Geriatrics & Gerontology International

Continuous S -(+)-ketamine administration during elective coronary artery bypass graft surgery attenuates pro-inflammatory cytokine response during and after cardiopulmonary bypass

(2010) I.D. Welters et al.   BRITISH JOURNAL OF ANAESTHESIA

Relationship of a common polymorphism of the glucocorticoid receptor gene to traumatic memories and posttraumatic stress disorder in patients after intensive care therapy

(2010) Daniela Hauer et al.   CRITICAL CARE MEDICINE

Is exogenous administration of IL-1ra (anakinra) likely to induce severe depression?

(2010) Annie Pierre Jonville-Bera et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Association of seropositivity for influenza and coronaviruses with history of mood disorders and suicide attempts

(2010) Olaoluwa Okusaga et al.   JOURNAL OF AFFECTIVE DISORDERS

Stress Controversies: Post-Traumatic Stress Disorder, Hippocampal Volume, Gastroduodenal Ulceration*

(2010) G. Fink   JOURNAL OF NEUROENDOCRINOLOGY

Status of Glucocorticoid Alterations in Post-traumatic Stress Disorder

(2009) Rachel Yehuda   Annals of the New York Academy of Sciences

Mental Morbidities and Chronic Fatigue in Severe Acute Respiratory Syndrome Survivors

(2009) Marco Ho-Bun Lam   ARCHIVES OF INTERNAL MEDICINE

Posttraumatic stress disorder in convalescent severe acute respiratory syndrome patients: a 4-year follow-up study

(2009) Xia Hong et al.   GENERAL HOSPITAL PSYCHIATRY

Influenza-associated central nervous system dysfunction: A literature review

(2008) Stephen Toovey   Travel Medicine and Infectious Disease

Pathogenetic mechanisms of severe acute respiratory syndrome

(2007) Yong Guo et al.   VIRUS RESEARCH