Neuropsychopharmacology of Emerging Drugs of Abuse: meta- and para-Halogen-Ring-Substituted α-PVP (“flakka”) Derivatives

Role of amino terminal substitutions in the pharmacological, rewarding and psychostimulant profiles of novel synthetic cathinones

(2021) L. Duart-Castells et al.   NEUROPHARMACOLOGY

The acute effects of multiple doses of methamphetamine on locomotor activity and anxiety-like behavior in adolescent and adult mice

(2021) Hayley A. Ortman et al.   BEHAVIOURAL BRAIN RESEARCH

Detection of 4-FMC, 4-MeO-α-PVP, 4-F-α-PVP, and PV8 in blood in a forensic case using liquid chromatography–electrospray ionization linear ion trap mass spectrometry

(2021) Akira Mochizuki et al.   FORENSIC SCIENCE INTERNATIONAL

Toxicological Analysis of Cases of Mixed Poisonings with Synthetic Cathinones and Other Drugs of Abuse

(2021) Ewelina Pieprzyca et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Structure–Activity Relationship of Novel Second-Generation Synthetic Cathinones: Mechanism of Action, Locomotion, Reward, and Immediate-Early Genes

(2021) Nuria Nadal-Gratacós et al.   Frontiers in Pharmacology

Designer drugs: mechanism of action and adverse effects

(2020) Dino Luethi et al.   ARCHIVES OF TOXICOLOGY

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

(2020) Nathalie Percie du Sert et al.   EXPERIMENTAL PHYSIOLOGY

Four Synthetic Cathinones: 3-Chloromethcathinone, 4-Chloromethcathinone, 4-Fluoro-α-Pyrrolidinopentiophenone, and 4-Methoxy-α-Pyrrolidinopentiophenone Produce Changes in the Spontaneous Locomotor Activity and Motor Performance in Mice with Varied Profiles

(2020) Jakub Wojcieszak et al.   NEUROTOXICITY RESEARCH

A review of synthetic cathinone-related fatalities from 2017 to 2020

(2020) Nunzia La Maida et al.   THERAPEUTIC DRUG MONITORING

Effects of N-ethylpentylone on locomotor activity and anxiety-like behavior in rats

(2019) Jiaolun Li et al.   BEHAVIOURAL PHARMACOLOGY

New psychoactive substances in oral fluid of drivers around a music festival in south-west France in 2017

(2019) Camille Richeval et al.   FORENSIC SCIENCE INTERNATIONAL

Abuse potential and toxicity of the synthetic cathinones (i.e., “Bath salts”)

(2019) Anthony L. Riley et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Para-Halogenation Affects Monoamine Transporter Inhibition Properties and Hepatocellular Toxicity of Amphetamines and Methcathinones

(2019) Dino Luethi et al.   Frontiers in Pharmacology

Changes in opiate and stimulant use through 10 years: The role of contextual factors, mental health disorders and psychosocial factors in a prospective SUD treatment cohort study

(2018) Grethe Lauritzen et al.   PLoS One

The abuse-related effects of pyrrolidine-containing cathinones are related to their potency and selectivity to inhibit the dopamine transporter

(2018) Brenda M. Gannon et al.   NEUROPSYCHOPHARMACOLOGY

Systematic Structure–Activity Studies on Selected 2-, 3-, and 4-Monosubstituted Synthetic Methcathinone Analogs as Monoamine Transporter Releasing Agents

(2018) Donna Walther et al.   ACS Chemical Neuroscience

Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters

(2018) Amy J. Eshleman et al.   PSYCHOPHARMACOLOGY

Brephedrone: A new psychoactive substance seized in Brazil

(2017) Yuri Machado et al.   FORENSIC SCIENCE INTERNATIONAL

Spectroscopic characterization and crystal structures of two cathinone derivatives: 1-(4-chlorophenyl)-2-(1-pyrrolidinyl)-pentan-1-one (4-chloro-α-PVP) sulfate and 1-(4-methylphenyl)-2-(dimethylamino)-propan-1-one (4-MDMC) hydrochloride salts, seized on illicit drug market

(2017) Piotr Kuś et al.   Forensic Toxicology

Identification and structural characterization of four novel synthetic cathinones: α-methylaminohexanophenone (hexedrone, HEX), 4-bromoethcathinone (4-BEC), 4-chloro-α-pyrrolidinopropiophenone (4-Cl-PPP), and 4-bromo-α-pyrrolidinopentiophenone (4-Br-PVP) after their seizures

(2017) Agata Błażewicz et al.   Forensic Toxicology

The newest cathinone derivatives as designer drugs: an analytical and toxicological review

(2017) Milena Majchrzak et al.   Forensic Toxicology

Patterns of use and toxicity of new para-halogenated substituted cathinones: 4-CMC (clephedrone), 4-CEC (4-chloroethcatinone) and 4-BMC (brephedrone)

(2017) Marc Grifell et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Core, social and moral disgust are bounded: A review on behavioral and neural bases of repugnance in clinical disorders

(2017) Carmelo M. Vicario et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Synthetic Cathinone and Cannabinoid Designer Drugs Pose a Major Risk for Public Health

(2017) Aviv M. Weinstein et al.   Frontiers in Psychiatry

Pharmacokinetic, Ambulatory, and Hyperthermic Effects of 3,4-Methylenedioxy-N-Methylcathinone (Methylone) in Rats

(2017) Kristýna Štefková et al.   Frontiers in Psychiatry

A snapshot on NPS in Italy: Distribution of drugs in seized materials analysed in an Italian forensic laboratory in the period 2013–2015

(2016) Sara Odoardi et al.   FORENSIC SCIENCE INTERNATIONAL

Fatal Intoxication with α-PVP, a Synthetic Cathinone Derivative

(2016) Barbara Potocka-Banaś et al.   JOURNAL OF FORENSIC SCIENCES

Self-administration and behavioral economics of second-generation synthetic cathinones in male rats

(2016) S.L. Huskinson et al.   PSYCHOPHARMACOLOGY

Quantitative structure-activity relationship analysis of the pharmacology ofpara-substituted methcathinone analogues

(2015) J S Bonano et al.   BRITISH JOURNAL OF PHARMACOLOGY

Monoamine transporter and receptor interaction profiles of novel psychoactive substances: Para-halogenated amphetamines and pyrovalerone cathinones

(2015) Anna Rickli et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

α-PVP (“flakka”): a new synthetic cathinone invades the drug arena

(2015) Maria Katselou et al.   Forensic Toxicology

Perspectives of Halogen Bonding Description in Scoring Functions and QSAR/QSPR: Substituent Effects in Aromatic Core

(2015) Oleg I. Titov et al.   Molecular Informatics

Neurotransmitter and psychostimulant recognition by the dopamine transporter

(2015) Kevin H. Wang et al.   NATURE

Use of the Open Field Maze to Measure Locomotor and Anxiety-like Behavior in Mice

(2015) Michael L. Seibenhener et al.   Jove-Journal of Visualized Experiments

Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products

(2014) Nahoko Uchiyama et al.   FORENSIC SCIENCE INTERNATIONAL

Sudden death after sustained restraint following self-administration of the designer drug α-pyrrolidinovalerophenone

(2014) Hisashi Nagai et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Substituted methcathinones differ in transporter and receptor interactions

(2013) Amy J. Eshleman et al.   BIOCHEMICAL PHARMACOLOGY

Mephedrone and methylenedioxypyrovalerone (MDPV), major constituents of “bath salts,” produce opposite effects at the human dopamine transporter

(2013) Krasnodara Cameron et al.   PSYCHOPHARMACOLOGY

The N Terminus of Monoamine Transporters Is a Lever Required for the Action of Amphetamines

(2010) Sonja Sucic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Instability of the ecstasy market and a new kid on the block: mephedrone

(2010) Tibor M Brunt et al.   JOURNAL OF PSYCHOPHARMACOLOGY