The Role of Inflammation in Retinal Neurodegeneration and Degenerative Diseases
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Title
The Role of Inflammation in Retinal Neurodegeneration and Degenerative Diseases
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 23, Issue 1, Pages 386
Publisher
MDPI AG
Online
2021-12-31
DOI
10.3390/ijms23010386
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Note: Only part of the references are listed.- Functional Characterization of Rare Genetic Variants in the N-Terminus of Complement Factor H in aHUS, C3G, and AMD
- (2021) Edwin K. S. Wong et al. Frontiers in Immunology
- Leber congenital amaurosis/early-onset severe retinal dystrophy: current management and clinical trials
- (2021) Malena Daich Varela et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Predicting quality of life in AMD patients—insights on the new NICE classification and on a bolt-on vision dimension for the EQ-5D
- (2021) Ricardo De Sousa Peixoto et al. EYE
- Retinal Inflammation, Cell Death and Inherited Retinal Dystrophies
- (2021) Lorena Olivares-González et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Leber Congenital Amaurosis Due to CEP290 Mutations – Severe Vision Impairment with a High Unmet Medical Need
- (2021) Bart P. Leroy et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- NLRP3 Inflammasome at the Interface of Inflammation, Endothelial Dysfunction, and Type 2 Diabetes
- (2021) Ilona M. Gora et al. Cells
- Mesenchymal Stem Cell-Based Therapy for Retinal Degenerative Diseases: Experimental Models and Clinical Trials
- (2021) Vladimir Holan et al. Cells
- Molecular Mechanisms Related to Oxidative Stress in Retinitis Pigmentosa
- (2021) Carla Enrica Gallenga et al. Antioxidants
- Gene Therapy in Inherited Retinal Diseases: An Update on Current State of the Art
- (2021) Alessia Amato et al. Frontiers in Medicine
- Risk factors for progression of age‐related macular degeneration
- (2020) Thomas J Heesterbeek et al. OPHTHALMIC AND PHYSIOLOGICAL OPTICS
- Monitoring progression of retinitis pigmentosa: current recommendations and recent advances
- (2020) Moreno Menghini et al. Expert Opinion on Orphan Drugs
- Age-related macular degeneration therapy
- (2020) Michael J. Ammar et al. CURRENT OPINION IN OPHTHALMOLOGY
- Microglia Contribution to the Regulation of the Retinal and Choroidal Vasculature in Age-Related Macular Degeneration
- (2020) C. Henrique Alves et al. Cells
- Intravitreal administration of adalimumab delays retinal degeneration in rd10 mice
- (2020) Lorena Olivares‐González et al. FASEB JOURNAL
- Oxidative Stress and Microglial Response in Retinitis Pigmentosa
- (2020) Yusuke Murakami et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Functional Roles of IL-33/ST2 Axis in Ocular Diseases
- (2020) Yujing Qian et al. MEDIATORS OF INFLAMMATION
- Distinct effects of complement and of NLRP3- and non-NLRP3 inflammasomes for choroidal neovascularization
- (2020) Jakob Malsy et al. eLife
- Night-vision aid using see-through display for patients with retinitis pigmentosa
- (2019) Yasuhiro Ikeda et al. JAPANESE JOURNAL OF OPHTHALMOLOGY
- Efficacy, Safety, and Durability of Voretigene Neparvovec-rzyl in RPE65 Mutation–Associated Inherited Retinal Dystrophy: Results of Phase 1 and 3 Trials
- (2019) Albert M. Maguire et al. OPHTHALMOLOGY
- A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration
- (2019) James T. Handa et al. Nature Communications
- IL-1 Family Members Mediate Cell Death, Inflammation and Angiogenesis in Retinal Degenerative Diseases
- (2019) Yvette Wooff et al. Frontiers in Immunology
- Oxidative Stress and Advanced Lipoxidation and Glycation End Products (ALEs and AGEs) in Aging and Age-Related Diseases
- (2019) Nurbubu T. Moldogazieva et al. Oxidative Medicine and Cellular Longevity
- Innate immune response in retinal homeostasis and inflammatory disorders
- (2019) Yusuke Murakami et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Microglia in Retinal Degeneration
- (2019) Khalid Rashid et al. Frontiers in Immunology
- (Z)-7,4'-Dimethoxy-6-hydroxy-aurone-4-O-β-glucopyranoside mitigates retinal degeneration in Rd10 mouse model through inhibiting oxidative stress and inflammatory responses
- (2019) You Chen et al. Cutaneous and Ocular Toxicology
- Gene Therapy in Retinal Dystrophies
- (2019) Ziccardi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment
- (2019) Josy Augustine et al. Journal of Neuroinflammation
- Progress in treating inherited retinal diseases: Early subretinal gene therapy clinical trials and candidates for future initiatives
- (2019) Alexandra V. Garafalo et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Physical activity, visual impairment, and eye disease
- (2018) Sharon R. Ong et al. EYE
- Treatments for dry age-related macular degeneration and Stargardt disease: a systematic review
- (2018) Norman Waugh et al. HEALTH TECHNOLOGY ASSESSMENT
- The Role of Microglia in Diabetic Retinopathy: Inflammation, Microvasculature Defects and Neurodegeneration
- (2018) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Chronic exposure to tumor necrosis factor alpha induces retinal pigment epithelium cell dedifferentiation
- (2018) Sara Touhami et al. Journal of Neuroinflammation
- The mechanism of cone cell death in Retinitis Pigmentosa
- (2018) Peter A. Campochiaro et al. PROGRESS IN RETINAL AND EYE RESEARCH
- NAD + and sirtuins in retinal degenerative diseases: A look at future therapies
- (2018) Jonathan B. Lin et al. PROGRESS IN RETINAL AND EYE RESEARCH
- IGF-1, Inflammation and Retinal Degeneration: A Close Network
- (2018) Ana I. Arroba et al. Frontiers in Aging Neuroscience
- Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa
- (2018) Thomas Blank et al. Frontiers in Immunology
- A network map of IL-33 signaling pathway
- (2018) Sneha M. Pinto et al. Journal of Cell Communication and Signaling
- Incidence and causes of visual impairment in Japan: the first nation-wide complete enumeration survey of newly certified visually impaired individuals
- (2018) Yuki Morizane et al. JAPANESE JOURNAL OF OPHTHALMOLOGY
- Sigma 1 receptor: A novel therapeutic target in retinal disease
- (2018) Sylvia B. Smith et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Intraocular cytokine profile and autoimmune reactions in retinitis pigmentosa, age-related macular degeneration, glaucoma and cataract
- (2018) Josianne C. ten Berge et al. ACTA OPHTHALMOLOGICA
- Transplantation of photoreceptors into the degenerative retina: Current state and future perspectives
- (2018) Sylvia J. Gasparini et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Immune cells in the retina and choroid: Two different tissue environments that require different defenses and surveillance
- (2018) Paul G. McMenamin et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Inflammasomes, the eye and anti-inflammasome therapy
- (2017) P Yerramothu et al. EYE
- Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation
- (2017) Bertrand Calippe et al. IMMUNITY
- Neuropeptides and Microglial Activation in Inflammation, Pain, and Neurodegenerative Diseases
- (2017) Lila Carniglia et al. MEDIATORS OF INFLAMMATION
- The complement system in age-related macular degeneration: A review of rare genetic variants and implications for personalized treatment
- (2017) Maartje J. Geerlings et al. MOLECULAR IMMUNOLOGY
- Strong upregulation of inflammatory genes accompanies photoreceptor demise in canine models of retinal degeneration
- (2017) Tatyana Appelbaum et al. PLoS One
- Unravelling the genetics of inherited retinal dystrophies: Past, present and future
- (2017) Suzanne Broadgate et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Inflammatory responses and inflammation-associated diseases in organs
- (2017) Linlin Chen et al. Oncotarget
- Vision impairment and major eye diseases reduce vision-specific emotional well-being in a Chinese population
- (2016) Eva K Fenwick et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Stargardt disease: clinical features, molecular genetics, animal models and therapeutic options
- (2016) Preena Tanna et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Inflammation and its role in age-related macular degeneration
- (2016) Anu Kauppinen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Microglial phagocytosis and activation underlying photoreceptor degeneration is regulated by CX3CL1-CX3CR1 signaling in a mouse model of retinitis pigmentosa
- (2016) Matthew K. Zabel et al. GLIA
- The broad-spectrum chemokine inhibitor NR58-3.14.3 modulates macrophage-mediated inflammation in the diseased retina
- (2016) Nilisha Fernando et al. Journal of Neuroinflammation
- Genetic factors associated with the development of age-related macular degeneration
- (2016) Olga Sergejeva et al. Medicina-Lithuania
- Control of the Inflammatory Macrophage Transcriptional Signature by miR-155
- (2016) Kyle A. Jablonski et al. PLoS One
- Risk factors and biomarkers of age-related macular degeneration
- (2016) Nathan G. Lambert et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Emerging therapies for inherited retinal degeneration
- (2016) H. P. N. Scholl et al. Science Translational Medicine
- p53 and the Carcinogenicity of Chronic Inflammation
- (2016) Andrei V. Gudkov et al. Cold Spring Harbor Perspectives in Medicine
- Subretinal mononuclear phagocytes induce cone segment loss via IL-1β
- (2016) Chiara M Eandi et al. eLife
- Genetic factors associated with the development of age-related macular degeneration
- (2016) Olga Sergejeva et al. Medicina-Lithuania
- Role of endocannabinoids in the progression of diabetic retinopathy
- (2015) Tapan Behl et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration
- (2015) O. Levy et al. EMBO Molecular Medicine
- Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration
- (2015) L. Zhao et al. EMBO Molecular Medicine
- Assessment of Retinal Function and Morphology in Aging Ccl2 Knockout Mice
- (2015) K. A. Vessey et al. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
- NRF2 promotes neuronal survival in neurodegeneration and acute nerve damage
- (2015) Wenjun Xiong et al. JOURNAL OF CLINICAL INVESTIGATION
- Progesterone receptor signalling in retinal photoreceptor neuroprotection
- (2015) Alice C. Wyse Jackson et al. JOURNAL OF NEUROCHEMISTRY
- Chemokine-mediated inflammation in the degenerating retina is coordinated by Müller cells, activated microglia, and retinal pigment epithelium
- (2015) Matt Rutar et al. Journal of Neuroinflammation
- Regulation of age-related macular degeneration-like pathology by complement factor H
- (2015) Christopher B. Toomey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Retinal microglia: Just bystander or target for therapy?
- (2015) Marcus Karlstetter et al. PROGRESS IN RETINAL AND EYE RESEARCH
- NLRP3 Inflammasome and Pathobiology in AMD
- (2015) Lucia Celkova et al. Journal of Clinical Medicine
- Analysis of Genetic and Environmental Risk Factors and Their Interactions in Korean Patients with Age-Related Macular Degeneration
- (2015) Se Joon Woo et al. PLoS One
- Spatiotemporal Cadence of Macrophage Polarisation in a Model of Light-Induced Retinal Degeneration
- (2015) Haihan Jiao et al. PLoS One
- Adalimumab Reduces Photoreceptor Cell Death in A Mouse Model of Retinal Degeneration
- (2015) Cristina Martínez-Fernández de la Cámara et al. Scientific Reports
- Age-Related Macular Degeneration: Genetics and Biology Coming Together
- (2014) Lars G. Fritsche et al. Annual Review of Genomics and Human Genetics
- Altered miRNA expression in canine retinas during normal development and in models of retinal degeneration
- (2014) Sem Genini et al. BMC GENOMICS
- Serum cytokines as biomarkers for age-related macular degeneration
- (2014) Khaled Nassar et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Intravitreal Sirolimus for the Treatment of Geographic Atrophy: Results of a Phase I/II Clinical Trial
- (2014) P. A. Petrou et al. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
- CCL3 Production by Microglial Cells Modulates Disease Severity in Murine Models of Retinal Degeneration
- (2014) H. Kohno et al. JOURNAL OF IMMUNOLOGY
- Microglia activation in a model of retinal degeneration and TUDCA neuroprotective effects
- (2014) Agustina Noailles et al. Journal of Neuroinflammation
- Suppression of Microglial Activation Is Neuroprotective in a Mouse Model of Human Retinitis Pigmentosa
- (2014) B. Peng et al. JOURNAL OF NEUROSCIENCE
- Cellular responses following retinal injuries and therapeutic approaches for neurodegenerative diseases
- (2014) Nicolás Cuenca et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Gene Therapy for Blindness
- (2013) José-Alain Sahel et al. Annual Review of Neuroscience
- CCR2+monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation inCx3cr1deficient mice
- (2013) Florian Sennlaub et al. EMBO Molecular Medicine
- Photoreceptor Proteins Initiate Microglial Activation via Toll-like Receptor 4 in Retinal Degeneration Mediated by All-trans-retinal
- (2013) Hideo Kohno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Outcome of ABCA4 Disease-Associated Alleles in Autosomal Recessive Retinal Dystrophies
- (2013) Rosa Riveiro-Alvarez et al. OPHTHALMOLOGY
- Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement
- (2013) A. V. Cideciyan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Caspase-7 ablation modulates UPR, reprograms TRAF2-JNK apoptosis and protects T17M rhodopsin mice from severe retinal degeneration
- (2013) S Choudhury et al. Cell Death & Disease
- Neuroprotective Strategies for the Treatment of Inherited Photoreceptor Degeneration
- (2012) D. Trifunovic et al. CURRENT MOLECULAR MEDICINE
- Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
- (2012) Charles A. Dinarello et al. NATURE REVIEWS DRUG DISCOVERY
- Clinical Evidence of Sustained Chronic Inflammatory Reaction in Retinitis Pigmentosa
- (2012) Noriko Yoshida et al. OPHTHALMOLOGY
- Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration
- (2012) Y. Murakami et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Optogenetic therapy for retinitis pigmentosa
- (2011) V Busskamp et al. GENE THERAPY
- Evidence of association ofAPOEwith age-related macular degeneration - a pooled analysis of 15 studies
- (2011) Gareth J. McKay et al. HUMAN MUTATION
- Accumulation of murine subretinal macrophages: effects of age, pigmentation and CX3CR1
- (2011) Holly R. Chinnery et al. NEUROBIOLOGY OF AGING
- Roles of IL-8 in Ocular Inflammations: A Review
- (2011) Hassan Ghasemi et al. OCULAR IMMUNOLOGY AND INFLAMMATION
- The Role of Tetracyclines in Rosacea
- (2010) Ali Alikhan et al. AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
- A Mutation in ZNF513, a Putative Regulator of Photoreceptor Development, Causes Autosomal-Recessive Retinitis Pigmentosa
- (2010) Lin Li et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A Novel Locus for Autosomal Recessive Retinitis Pigmentosa in a Consanguineous Pakistani Family Maps to Chromosome 2p
- (2010) Shagufta Naz et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Pattern Recognition Receptors and Inflammation
- (2010) Osamu Takeuchi et al. CELL
- The role of anti-inflammatory agents in age-related macular degeneration (AMD) treatment
- (2010) Y Wang et al. EYE
- TOPORS, implicated in retinal degeneration, is a cilia-centrosomal protein
- (2010) Christina F. Chakarova et al. HUMAN MOLECULAR GENETICS
- Nonsteroidal Anti-inflammatory Drugs in Ophthalmology
- (2010) Stephen J. Kim et al. SURVEY OF OPHTHALMOLOGY
- Mutations in a BTB-Kelch Protein, KLHL7, Cause Autosomal-Dominant Retinitis Pigmentosa
- (2009) James S. Friedman et al. AMERICAN JOURNAL OF HUMAN GENETICS
- NADPH oxidase plays a central role in cone cell death in retinitis pigmentosa
- (2009) Shinichi Usui et al. JOURNAL OF NEUROCHEMISTRY
- Interleukin-8 promoter polymorphism -251A/T is a risk factor for age-related macular degeneration
- (2008) S V Goverdhan et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- IL-33 reduces the development of atherosclerosis
- (2008) Ashley M. Miller et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa
- (2008) Claudio Punzo et al. NATURE NEUROSCIENCE
- Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis
- (2008) Albert M. Maguire et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis
- (2008) James W.B. Bainbridge et al. NEW ENGLAND JOURNAL OF MEDICINE
- Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics
- (2008) A. V. Cideciyan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Leber congenital amaurosis: Genes, proteins and disease mechanisms
- (2008) Anneke I. den Hollander et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Molecular pathology of age-related macular degeneration
- (2008) Xiaoyan Ding et al. PROGRESS IN RETINAL AND EYE RESEARCH
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