Insight into the Binding and Hydrolytic Preferences of hNudt16 Based on Nucleotide Diphosphate Substrates

Halogen Atoms in the Protein–Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2

(2021) Honorata Czapinska et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Nudix Hydrolase NUDT16 Regulates 53BP1 Protein by Reversing 53BP1 ADP-Ribosylation

(2020) Fan Zhang et al.   CANCER RESEARCH

Fluorescent probe displacement assays reveal unique nucleic acid binding properties of human nudix enzymes

(2020) Atreyei Ray et al.   ANALYTICAL BIOCHEMISTRY

Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs

(2020) Sunny Sharma et al.   NUCLEIC ACIDS RESEARCH

In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization

(2020) Maurice Michel et al.   Frontiers in Chemistry

Role of NUDIX Hydrolases in NAD and ADP-Ribose Metabolism in Mammals

(2020) V. A. Kulikova et al.   BIOCHEMISTRY-MOSCOW

Structural analyses of NudT16–ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins

(2019) Puchong Thirawatananond et al.   Scientific Reports

Reversible ADP-ribosylation of RNA

(2019) Deeksha Munnur et al.   NUCLEIC ACIDS RESEARCH

BeStSel: a web server for accurate protein secondary structure prediction and fold recognition from the circular dichroism spectra

(2018) András Micsonai et al.   NUCLEIC ACIDS RESEARCH

Hydrolytic activity of human Nudt16 enzyme on dinucleotide cap analogs and short capped oligonucleotides

(2018) Renata Grzela et al.   RNA

A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family

(2017) Jordi Carreras-Puigvert et al.   Nature Communications

ITC-derived binding affinity may be biased due to titrant (nano)-aggregation. Binding of halogenated benzotriazoles to the catalytic domain of human protein kinase CK2

(2017) Maria Winiewska et al.   PLoS One

ENPP1 processes protein ADP-ribosylationin vitro

(2016) Luca Palazzo et al.   FEBS Journal

Clickable trimethylguanosine cap analogs modified within the triphosphate bridge: synthesis, conjugation to RNA and susceptibility to degradation

(2016) Blazej A. Wojtczak et al.   RSC Advances

The Guanine-Based Purinergic System: The Tale of An Orphan Neuromodulation

(2016) Valentina Di Liberto et al.   Frontiers in Pharmacology

Processing of protein ADP-ribosylation by Nudix hydrolases

(2015) Luca Palazzo et al.   BIOCHEMICAL JOURNAL

Accurate secondary structure prediction and fold recognition for circular dichroism spectroscopy

(2015) András Micsonai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate

(2015) Lionel Trésaugues et al.   PLoS One

MicroScale Thermophoresis: Interaction analysis and beyond

(2014) Moran Jerabek-Willemsen et al.   JOURNAL OF MOLECULAR STRUCTURE

Differential utilization of decapping enzymes in mammalian mRNA decay pathways

(2011) Y. Li et al.   RNA

hNUDT16: a universal decapping enzyme for small nucleolar RNA and cytoplasmic mRNA

(2011) Guangwen Lu et al.   Protein & Cell

Multiple mRNA Decapping Enzymes in Mammalian Cells

(2010) Man-Gen Song et al.   MOLECULAR CELL

NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest

(2010) Teruaki Iyama et al.   NUCLEIC ACIDS RESEARCH

NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals

(2010) Nona Abolhassani et al.   NUCLEIC ACIDS RESEARCH

Dinucleoside polyphosphates: strong endogenous agonists of the purinergic system

(2009) Vera Jankowski et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Quantitative Model of Thermal Stabilization and Destabilization of Proteins by Ligands

(2008) Piotras Cimmperman et al.   BIOPHYSICAL JOURNAL

The generalized Born/volume integral implicit solvent model: Estimation of the free energy of hydration using London dispersion instead of atomic surface area

(2008) Paul Labute   JOURNAL OF COMPUTATIONAL CHEMISTRY

Evolutionary conservation supports ancient origin for Nudt16, a nuclear-localized, RNA-binding, RNA-decapping enzyme

(2008) Melissa J. Taylor et al.   NUCLEIC ACIDS RESEARCH