NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest

NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals

(2010) Nona Abolhassani et al.   NUCLEIC ACIDS RESEARCH

Recognition and Processing of a New Repertoire of DNA Substrates by Human 3-Methyladenine DNA Glycosylase (AAG)†

(2009) Chun-Yue I. Lee et al.   BIOCHEMISTRY

ITPase-deficient mice show growth retardation and die before weaning

(2009) M Behmanesh et al.   CELL DEATH AND DIFFERENTIATION

Checkpoint mechanisms at the intersection between DNA damage and repair

(2009) Federico Lazzaro et al.   DNA REPAIR

Mouse RS21-C6 is a mammalian 2′-deoxycytidine 5′-triphosphate pyrophosphohydrolase that prefers 5-iodocytosine

(2009) Mari Nonaka et al.   FEBS Journal

Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence

(2009) P. Rai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells

(2008) Muralidhar L Hegde et al.   CELL RESEARCH

Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs

(2008) Sugako Oka et al.   EMBO JOURNAL

Miscoding Properties of 2′-Deoxyinosine, a Nitric Oxide-Derived DNA Adduct, during Translesion Synthesis Catalyzed by Human DNA Polymerases

(2008) Manabu Yasui et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantification of DNA damage products resulting from deamination, oxidation and reaction with products of lipid peroxidation by liquid chromatography isotope dilution tandem mass spectrometry

(2008) Koli Taghizadeh et al.   Nature Protocols

Removal of deoxyinosine from the Escherichia coli chromosome as studied by oligonucleotide transformation

(2007) Bernard Weiss   DNA REPAIR