Reversible ADP-ribosylation of RNA

Insights into the biogenesis, function, and regulation of ADP-ribosylation

(2018) Michael S Cohen et al.   Nature Chemical Biology

Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation

(2018) Gabriella Zarkovic et al.   NUCLEIC ACIDS RESEARCH

Two-step mechanism and step-arrest mutants of Runella slithyformis NAD+-dependent tRNA 2'-phosphotransferase Tpt1

(2018) Annum Munir et al.   RNA

Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis

(2018) Anthony R. Fehr et al.   TRENDS IN MICROBIOLOGY

Dna is a New Target of Parp3

(2018) E. A. Belousova et al.   Scientific Reports

Serine is the major residue for ADP-ribosylation upon DNA damage

(2018) Luca Palazzo et al.   eLife

MacroD1 Is a Promiscuous ADP-Ribosyl Hydrolase Localized to Mitochondria

(2018) Thomas Agnew et al.   Frontiers in Microbiology

NAD+-dependent synthesis of a 5′-phospho-ADP-ribosylated RNA/DNA cap by RNA 2′-phosphotransferase Tpt1

(2018) Annum Munir et al.   NUCLEIC ACIDS RESEARCH

Reversible mono-ADP-ribosylation of DNA breaks

(2017) Deeksha Munnur et al.   FEBS Journal

ADP-ribosylation: new facets of an ancient modification

(2017) Luca Palazzo et al.   FEBS Journal

Serine ADP-Ribosylation Depends on HPF1

(2017) Juan José Bonfiglio et al.   MOLECULAR CELL

ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence

(2017) Robert Lyle McPherson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serine ADP-ribosylation reversal by the hydrolase ARH3

(2017) Pietro Fontana et al.   eLife

The conserved macrodomains of the non-structural proteins of Chikungunya virus and other pathogenic positive strand RNA viruses function as mono-ADP-ribosylhydrolases

(2017) Laura Eckei et al.   Scientific Reports

Macrodomains: Structure, Function, Evolution, and Catalytic Activities

(2016) Johannes Gregor Matthias Rack et al.   Annual Review of Biochemistry

ENPP1 processes protein ADP-ribosylationin vitro

(2016) Luca Palazzo et al.   FEBS Journal

Viral Macro Domains Reverse Protein ADP-Ribosylation

(2016) Changqing Li et al.   JOURNAL OF VIROLOGY

The Toxin-Antitoxin System DarTG Catalyzes Reversible ADP-Ribosylation of DNA

(2016) Gytis Jankevicius et al.   MOLECULAR CELL

HPF1/C4orf27 Is a PARP-1-Interacting Protein that Regulates PARP-1 ADP-Ribosylation Activity

(2016) Ian Gibbs-Seymour et al.   MOLECULAR CELL

Serine is a new target residue for endogenous ADP-ribosylation on histones

(2016) Orsolya Leidecker et al.   Nature Chemical Biology

The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection

(2016) Anthony R. Fehr et al.   mBio

Identifying Family-Member-Specific Targets of Mono-ARTDs by Using a Chemical Genetics Approach

(2016) Ian Carter-O’Connell et al.   Cell Reports

Processing of protein ADP-ribosylation by Nudix hydrolases

(2015) Luca Palazzo et al.   BIOCHEMICAL JOURNAL

Towards small molecule inhibitors of mono-ADP-ribosyltransferases

(2015) Torun Ekblad et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Dimeric ADP-Ribose and Its Structure with Human Poly(ADP-ribose) Glycohydrolase

(2015) Michael J. Lambrecht et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain

(2015) Jennine M. Dawicki-McKenna et al.   MOLECULAR CELL

Distribution of protein poly(ADP-ribosyl)ation systems across all domains of life

(2014) Dragutin Perina et al.   DNA REPAIR

The ADP-ribosyltransferase PARP10/ARTD10 Interacts with Proliferating Cell Nuclear Antigen (PCNA) and Is Required for DNA Damage Tolerance

(2014) Claudia M. Nicolae et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineering the Substrate Specificity of ADP-Ribosyltransferases for Identifying Direct Protein Targets

(2014) Ian Carter-O’Connell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Family-wide analysis of poly(ADP-ribose) polymerase activity

(2014) Sejal Vyas et al.   Nature Communications

Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease

(2013) Reza Sharifi et al.   EMBO JOURNAL

Caspase-dependent cleavage of the mono-ADP-ribosyltransferase ARTD10 interferes with its pro-apoptotic function

(2013) Nicolas Herzog et al.   FEBS Journal

Interferon-Stimulated Poly(ADP-Ribose) Polymerases Are Potent Inhibitors of Cellular Translation and Virus Replication

(2013) S. Atasheva et al.   JOURNAL OF VIROLOGY

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases

(2013) Florian Rosenthal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A family of macrodomain proteins reverses cellular mono-ADP-ribosylation

(2013) Gytis Jankevicius et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

(2013) Patricia Verheugd et al.   Nature Communications

Dynamic subcellular localization of the mono-ADP-ribosyltransferase ARTD10 and interaction with the ubiquitin receptor p62

(2012) Henning Kleine et al.   Cell Communication and Signaling

New PARP Gene with an Anti-Alphavirus Function

(2012) S. Atasheva et al.   JOURNAL OF VIROLOGY

Identification of novel components of NAD-utilizing metabolic pathways and prediction of their biochemical functions

(2012) Robson Francisco de Souza et al.   Molecular BioSystems

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

(2012) Miri Jwa et al.   NATURE CELL BIOLOGY

New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

(2012) Bryan A. Gibson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of Macrodomain Proteins as NovelO-Acetyl-ADP-ribose Deacetylases

(2011) Dawei Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase

(2011) Dea Slade et al.   NATURE

Toward a unified nomenclature for mammalian ADP-ribosyltransferases

(2010) Michael O. Hottiger et al.   TRENDS IN BIOCHEMICAL SCIENCES

Differential Activities of Cellular and Viral Macro Domain Proteins in Binding of ADP-Ribose Metabolites

(2008) Maarit Neuvonen et al.   JOURNAL OF MOLECULAR BIOLOGY

Substrate-Assisted Catalysis by PARP10 Limits Its Activity to Mono-ADP-Ribosylation

(2008) Henning Kleine et al.   MOLECULAR CELL