Ovarian Cancer Cells in Ascites Form Aggregates That Display a Hybrid Epithelial-Mesenchymal Phenotype and Allows Survival and Proliferation of Metastasizing Cells

Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer

(2020) Anders Etzerodt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The untapped potential of ascites in ovarian cancer research and treatment

(2020) Caroline Elizabeth Ford et al.   BRITISH JOURNAL OF CANCER

Different Shades of L1CAM in the Pathophysiology of Cancer Stem Cells

(2020) Marco Giordano et al.   Journal of Clinical Medicine

A Novel Role for NUAK1 in Promoting Ovarian Cancer Metastasis through Regulation of Fibronectin Production in Spheroids

(2020) Jamie Lee Fritz et al.   Cancers

Upregulation of mesothelial genes in ovarian carcinoma cells is associated with an unfavorable clinical outcome and the promotion of cancer cell adhesion

(2020) Kaire Ojasalu et al.   Molecular Oncology

A single-cell landscape of high-grade serous ovarian cancer

(2020) Benjamin Izar et al.   NATURE MEDICINE

Proline-rich tyrosine kinase 2 mediates transforming growth factor-beta-induced hepatic stellate cell activation and liver fibrosis

(2020) Jonghwa Kim et al.   Scientific Reports

Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer

(2019) Qinglei Gao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor cell‑fibroblast heterotypic aggregates in�malignant ascites of patients with ovarian cancer

(2019) Qing Han et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Ovarian Cancer Dissemination—A Cell Biologist’s Perspective

(2019) Sadaf Farsinejad et al.   Cancers

Multicellular detachment generates metastatic spheroids during intra-abdominal dissemination in epithelial ovarian cancer

(2018) Sara Al Habyan et al.   ONCOGENE

Expression and prognostic significance of epithelial-mesenchymal transition-related markers and phenotype in serous ovarian cancer

(2018) In Hye Song et al.   PATHOLOGY RESEARCH AND PRACTICE

Evaluating Tumor Evolution via Genomic Profiling of Individual Tumor Spheroids in a Malignant Ascites

(2018) Sungsik Kim et al.   Scientific Reports

Cell type-selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment

(2018) Silke Reinartz et al.   Molecular Oncology

Cadherin composition and multicellular aggregate invasion in organotypic models of epithelial ovarian cancer intraperitoneal metastasis

(2017) Y Klymenko et al.   ONCOGENE

An integrated analysis identifies STAT4 as a key regulator of ovarian cancer metastasis

(2017) L Zhao et al.   ONCOGENE

Mesothelial cells interact with tumor cells for the formation of ovarian cancer multicellular spheroids in peritoneal effusions

(2016) Isabelle Matte et al.   CLINICAL & EXPERIMENTAL METASTASIS

Tumor-associated macrophages drive spheroid formation during early transcoelomic metastasis of ovarian cancer

(2016) Mingzhu Yin et al.   JOURNAL OF CLINICAL INVESTIGATION

Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer

(2016) Andrew McPherson et al.   NATURE GENETICS

TGFβ signaling regulates epithelial–mesenchymal plasticity in ovarian cancer ascites-derived spheroids

(2015) Samah Rafehi et al.   ENDOCRINE-RELATED CANCER

Peritoneal and hematogenous metastases of ovarian cancer cells are both controlled by the p90RSK through a self-reinforcing cell autonomous mechanism

(2015) Erica Torchiaro et al.   Oncotarget

Mesenchymal gene program–expressing ovarian cancer spheroids exhibit enhanced mesothelial clearance

(2014) Rachel A. Davidowitz et al.   JOURNAL OF CLINICAL INVESTIGATION

Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion

(2014) Hilary A. Kenny et al.   JOURNAL OF CLINICAL INVESTIGATION

Ovarian cancer ascites-derived vitronectin and fibronectin: Combined purification, molecular features and effects on cell response

(2013) Ludovic Carduner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Transformation of the Fallopian Tube Secretory Epithelium Leads to High-Grade Serous Ovarian Cancer in Brca;Tp53;Pten Models

(2013) Ruth Perets et al.   CANCER CELL

Epithelial-Mesenchymal Transition Associates with Maintenance of Stemness in Spheroid-Derived Stem-Like Colon Cancer Cells

(2013) Xiao-Yan Han et al.   PLoS One

Ascites analysis by a microfluidic chip allows tumor-cell profiling

(2013) V. M. Peterson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of PAX8 and p53 is beneficial in recognizing metastatic carcinomas in pelvic washings, especially in cases with suspicious cytology

(2012) Li Xiang et al.   GYNECOLOGIC ONCOLOGY

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Isolation and Characterization of Tumor Cells from the Ascites of Ovarian Cancer Patients: Molecular Phenotype of Chemoresistant Ovarian Tumors

(2012) Ardian Latifi et al.   PLoS One

A Comprehensive Analysis of PAX8 Expression in Human Epithelial Tumors

(2011) Anna R. Laury et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Ovarian Cancer Spheroids Use Myosin-Generated Force to Clear the Mesothelium

(2011) Marcin P. Iwanicki et al.   Cancer Discovery

Ovarian Cancer Development and Metastasis

(2010) Ernst Lengyel   AMERICAN JOURNAL OF PATHOLOGY

PAX8 Reliably Distinguishes Ovarian Serous Tumors From Malignant Mesothelioma

(2010) Anna R. Laury et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments

(2010) Isabelle Tanjoni et al.   CANCER BIOLOGY & THERAPY

Multicellular spheroids in ovarian cancer metastases: Biology and pathology

(2009) Kristy Shield et al.   GYNECOLOGIC ONCOLOGY