Cardioprotection of Immature Heart by Simultaneous Activation of PKA and Epac: A Role for the Mitochondrial Permeability Transition Pore

Preconditioning or Postconditioning with 8-Br-cAMP-AM Protects the Heart against Regional Ischemia and Reperfusion: A Role for Mitochondrial Permeability Transition

(2021) Igor Khaliulin et al.   Cells

Consecutive Isoproterenol and Adenosine Treatment Confers Marked Protection against Reperfusion Injury in Adult but Not in Immature Heart: A Role for Glycogen

(2018) Martin Lewis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cardioprotection by exenatide: A novel mechanism via improving mitochondrial function involving the GLP-1 receptor/cAMP/PKA pathway

(2017) Guanglei Chang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Role of the MPTP in conditioning the heart - translatability and mechanism

(2015) S-B Ong et al.   BRITISH JOURNAL OF PHARMACOLOGY

The mitochondrial permeability transition pore and its role in myocardial ischemia reperfusion injury

(2015) Sang-Bing Ong et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

β-adrenergic stimulation activates protein kinase Cε and induces extracellular signal-regulated kinase phosphorylation and cardiomyocyte hypertrophy

(2015) LIN LI et al.   Molecular Medicine Reports

Developmental determinants of cardiac sensitivity to hypoxia

(2014) Bohuslav Ostadal et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Mapping Genetic Contributions to Cardiac Pathology Induced by Beta-Adrenergic Stimulation in MiceCLINICAL PERSPECTIVE

(2014) Christoph D. Rau et al.   Circulation-Cardiovascular Genetics

10 Cell-Permeable Cyclic AMP as a Novel Cardioprotective Agent

(2014) D J Dudley et al.   HEART

Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses

(2014) Satoshi Okumura et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinically-relevant consecutive treatment with isoproterenol and adenosine protects the failing heart against ischaemia and reperfusion

(2014) Igor Khaliulin et al.   Journal of Translational Medicine

Adrenergic Nervous System in Heart Failure

(2013) Anastasios Lymperopoulos et al.   CIRCULATION RESEARCH

Targeting cardiac β-adrenergic signaling via GRK2 inhibition for heart failure therapy

(2013) Alessandro Cannavo et al.   Frontiers in Physiology

Activation of a Cyclic Amp-Guanine Exchange Factor in Hepatocytes Decreases Nitric Oxide Synthase Expression

(2012) Baochun Zhang et al.   SHOCK

Type 10 adenylyl cyclase mediates mitochondrial Bax translocation and apoptosis of adult rat cardiomyocytes under simulated ischaemia/reperfusion

(2011) Avinash Appukuttan et al.   CARDIOVASCULAR RESEARCH

Epac enhances excitation–transcription coupling in cardiac myocytes

(2011) Laetitia Pereira et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

Consecutive pharmacological activation of PKA and PKC mimics the potent cardioprotection of temperature preconditioning

(2010) Igor Khaliulin et al.   CARDIOVASCULAR RESEARCH

Epac stimulation induces rapid increases in connexin43 phosphorylation and function without preconditioning effect

(2010) Nicolas Duquesnes et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

PKA, Rap1, ERK1/2, and p90RSK mediate PGE2 and EP4 signaling in neonatal ventricular myocytes

(2009) Quan He et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The role of the mitochondrial permeability transition pore in heart disease

(2009) Andrew P. Halestrap et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The cAMP binding protein Epac regulates cardiac myofilament function

(2009) O. Cazorla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of GSK3β by Postconditioning Is Required to Prevent Opening of the Mitochondrial Permeability Transition Pore During Reperfusion

(2008) Ludovic Gomez et al.   CIRCULATION