Estradiol Signaling at the Heart of Folliculogenesis: Its Potential Deregulation in Human Ovarian Pathologies

Estradiol Regulates mRNA Levels of Estrogen Receptor Beta 4 and Beta 5 Isoforms and Modulates Human Granulosa Cell Apoptosis

(2021) Alice Pierre et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Estradiol promotes cell survival and induces Greb1 expression in granulosa cell tumors of the ovary through an ERα ‐dependent mechanism

(2021) Victoria Cluzet et al.   JOURNAL OF PATHOLOGY

Estrogenic control of mitochondrial function

(2020) Carolyn M. Klinge   Redox Biology

Estrogen receptor β exerts tumor suppressive effects in prostate cancer through repression of androgen receptor activity

(2020) Surendra Chaurasiya et al.   PLoS One

Mechanisms of estradiol-induced EGF-like factor expression and oocyte maturation via G protein-coupled estrogen receptor

(2020) Hui Zhang et al.   ENDOCRINOLOGY

Estrogen Receptor Beta (ERβ): A Ligand Activated Tumor Suppressor

(2020) Rahul Mal et al.   Frontiers in Oncology

New Anti-Müllerian Hormone Target Genes Involved in Granulosa Cell Survival in Women With Polycystic Ovary Syndrome

(2020) Chrystèle Racine et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The association between progesterone receptor expression and survival in women with adult granulosa cell tumors

(2019) Allison M. Puechl et al.   GYNECOLOGIC ONCOLOGY

Emerging biomarkers in ovarian granulosa cell tumors

(2019) Anne M Mills et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Expression of genes controlling steroid metabolism and action in granulosa-lutein cells of women with polycystic ovaries

(2019) A. Lerner et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Gene expression in granulosa cells from small antral follicles from women with or without polycystic ovaries

(2019) Lisa Ann Owens et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Aberrant granulosa cell-fate related to inactivated p53/Rb signaling contributes to granulosa cell tumors and to FOXL2 downregulation in the mouse ovary

(2019) Victoria Cluzet et al.   ONCOGENE

Melatonin Reduces Androgen Production and Upregulates Heme Oxygenase-1 Expression in Granulosa Cells from PCOS Patients with Hypoestrogenia and Hyperandrogenia

(2019) Kun Yu et al.   Oxidative Medicine and Cellular Longevity

Differential effects of estrogen receptor beta isoforms on glioblastoma progression

(2018) Jinyou Liu et al.   CANCER RESEARCH

Duality of estrogen receptor β action in cancer progression

(2018) TC Guillette et al.   CURRENT OPINION IN PHARMACOLOGY

Estrogen Receptors: New Directions in the New Millennium

(2018) Sylvia C Hewitt et al.   ENDOCRINE REVIEWS

Estrogen receptor β: Potential target for therapy in adult granulosa cell tumors?

(2018) Alessandra Ciucci et al.   GYNECOLOGIC ONCOLOGY

ESR2 regulates granulosa cell genes essential for follicle maturation and ovulation

(2018) Vincentaben Khristi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The molecular mechanism of ovarian granulosa cell tumors

(2018) Jiaheng Li et al.   Journal of Ovarian Research

The estrogen receptor: two or more molecules, multiple variants, diverse localizations, signaling and functions. Are we undergoing a paradigm-shift as regards their significance in breast cancer?

(2018) Marilena Kampa et al.   Hormones-International Journal of Endocrinology and Metabolism

Early onset complete ovarian failure and lack of puberty in a woman with mutated estrogen receptor beta (ESR2)

(2018) Mariarosaria Lang-Muritano et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Expression and Mutation Analyses of Fas, FLIP and Bcl-2 in Granulosa Cell Tumor of Ovary

(2018) Nam Jin Yoo et al.   TUMORI

Estrogen receptor β is associated with expression of cancer associated genes and survival in ovarian cancer

(2018) Susanne Schüler-Toprak et al.   BMC CANCER

Elevation of antimüllerian hormone in women with polycystic ovary syndrome undergoing assisted reproduction: effect of insulin

(2018) Xing Yan Liu et al.   FERTILITY AND STERILITY

The estrogen receptor variants β2 and β5 induce stem cell characteristics and chemotherapy resistance in prostate cancer through activation of hypoxic signaling

(2018) Michelle Faria et al.   Oncotarget

Geographical Prevalence of Polycystic Ovary Syndrome as Determined by Region and Race/Ethnicity

(2018) Wendy Wolf et al.   International Journal of Environmental Research and Public Health

Exploring the Impact of Single-Nucleotide Polymorphisms on Translation

(2018) Francis Robert et al.   Frontiers in Genetics

Biallelic and monoallelic ESR2 variants associated with 46,XY disorders of sex development

(2017) Dorien Baetens et al.   GENETICS IN MEDICINE

Dysregulation of the Anti-Müllerian Hormone System by Steroids in Women With Polycystic Ovary Syndrome

(2017) Alice Pierre et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity

(2017) Adam W. Nelson et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Therapeutic utility of natural estrogen receptor beta agonists on ovarian cancer

(2017) Jinyou Liu et al.   Oncotarget

Altered FoxO3 expression and apoptosis in granulosa cells of women with polycystic ovary syndrome

(2016) Saideh Mikaeili et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Differential Activation of a Mouse Estrogen Receptor β Isoform (mERβ2) with Endocrine-Disrupting Chemicals (EDCs)

(2016) Lauren J. Donoghue et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Interactions between androgens, FSH, anti-Müllerian hormone and estradiol during folliculogenesis in the human normal and polycystic ovary

(2016) Didier Dewailly et al.   HUMAN REPRODUCTION UPDATE

Impact of FOXL2 mutations on signaling in ovarian granulosa cell tumors

(2016) Dilys T.H. Leung et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Expression of P450 Aromatase in Granulosa Cell Tumors and Sertoli-Stromal Cell Tumors of the Ovary

(2016) Noriko Kato et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Estrogen receptor beta modulates breast cancer cells functional properties, signaling and expression of matrix molecules

(2016) Zoi Piperigkou et al.   MATRIX BIOLOGY

The Emerging Role of FOXL2 in Regulating the Transcriptional Activation Function of Estrogen Receptor β

(2016) Mana Hirano et al.   Reproductive Sciences

Translational control by 5'-untranslated regions of eukaryotic mRNAs

(2016) A. G. Hinnebusch et al.   SCIENCE

Expression pattern of G protein‑coupled estrogen receptor 1 (GPER) in human cumulus granulosa cells (CGCs) of patients with PCOS

(2016) Lili Zang et al.   Systems Biology in Reproductive Medicine

Evaluation of response to hormone therapy in patients with measurable adult granulosa cell tumors of the ovary

(2015) Hannah S. van Meurs et al.   ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA

17β-estradiol inhibits spreading of metastatic cells from granulosa cell tumors through a non-genomic mechanism involving GPER1

(2015) Charlotte M. François et al.   CARCINOGENESIS

Hormone receptors as a marker of poor survival in epithelial ovarian cancer

(2015) Michel van Kruchten et al.   GYNECOLOGIC ONCOLOGY

Estrogen and progesterone receptor subtype expression in granulosa cells from women with polycystic ovary syndrome

(2015) Tayebeh Artimani et al.   GYNECOLOGICAL ENDOCRINOLOGY

The clinical utility of serum anti-Müllerian hormone in the follow-up of ovarian adult-type granulosa cell tumors-A comparative study with inhibin B

(2015) Anniina Färkkilä et al.   INTERNATIONAL JOURNAL OF CANCER

Proteomics of Follicular Fluid From Women With Polycystic Ovary Syndrome Suggests Molecular Defects in Follicular Development

(2015) Aditi S. Ambekar et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Phosphorylation Alters Oestrogen Receptor β-Mediated Transcription in Neurones

(2015) E. Pinceti et al.   JOURNAL OF NEUROENDOCRINOLOGY

What have we learned about GPER function in physiology and disease from knockout mice?

(2015) Eric R. Prossnitz et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Estrogen receptor alpha-36 (ER-α36): A new player in human breast cancer

(2015) Zhao-Yi Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Prognostic significance of the estrogen receptor beta (ERβ) isoforms ERβ1, ERβ2, and ERβ5 in advanced serous ovarian cancer

(2014) Alessandra Ciucci et al.   GYNECOLOGIC ONCOLOGY

The G-Protein-Coupled Estrogen Receptor (GPER/GPR30) in Ovarian Granulosa Cell Tumors

(2014) Sabine Heublein et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Estrogen receptor mutation in a girl with primary amenorrhea

(2013) M Asadi et al.   CLINICAL GENETICS

A bi-faceted role of estrogen receptor β in breast cancer

(2013) Etienne Leygue et al.   ENDOCRINE-RELATED CANCER

Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogens

(2013) Yan Jiang et al.   FASEB JOURNAL

Promoter Methylation ofCYP19A1Gene in Chinese Polycystic Ovary Syndrome Patients

(2013) Ying-Ying Yu et al.   GYNECOLOGIC AND OBSTETRIC INVESTIGATION

Different associations of estrogen receptor β isoforms, ERβ1 and ERβ2, expression levels with tumor size and survival in early- and late-onset breast cancer

(2012) Vesna Mandusic et al.   CANCER LETTERS

Molecular Pathogenesis of Granulosa Cell Tumors of the Ovary

(2012) Stacey Jamieson et al.   ENDOCRINE REVIEWS

Differential Regulation of Ovarian Anti-Müllerian Hormone (AMH) by Estradiol through α- and β-Estrogen Receptors

(2012) Michaël Grynberg et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Characterisation of Human Oestrogen Receptor beta (ERβ) Splice Variants in Neuronal Cells

(2012) N. N. Mott et al.   JOURNAL OF NEUROENDOCRINOLOGY

Estrogen Receptors β1 and β2 Have Opposing Roles in Regulating Proliferation and Bone Metastasis Genes in the Prostate Cancer Cell Line PC3

(2012) Prasenjit Dey et al.   MOLECULAR ENDOCRINOLOGY

Immunohistochemical expression and prognostic significance of oestrogen receptor-alpha, oestrogen receptor-beta, and progesterone receptor in stage 1 adult-type granulosa cell tumour of the ovary

(2012) S.M. Hutton et al.   PATHOLOGY

Potential Role of Estrogen Receptor Beta as a Tumor Suppressor of Epithelial Ovarian Cancer

(2012) Carine Bossard et al.   PLoS One

Cracking the Estrogen Receptor's Posttranslational Code in Breast Tumors

(2011) Muriel Le Romancer et al.   ENDOCRINE REVIEWS

Anti-Müllerian hormone reduces follicle sensitivity to follicle-stimulating hormone in human granulosa cells

(2011) Laura Pellatt et al.   FERTILITY AND STERILITY

Cytoplasmic expression of estrogen receptor beta (ERβ) predicts poor clinical outcome in advanced serous ovarian cancer

(2011) Ilaria De Stefano et al.   GYNECOLOGIC ONCOLOGY

Ovarian antral folliculogenesis during the human menstrual cycle: a review

(2011) Angela R. Baerwald et al.   HUMAN REPRODUCTION UPDATE

Estrogen Receptor  : Switching to a New Partner and Escaping from Estrogen

(2011) Y.-K. Leung et al.   Science Signaling

Expression of oestrogen receptor β isoforms is regulated by transcriptional and post-transcriptional mechanisms

(2010) Laura Smith et al.   BIOCHEMICAL JOURNAL

Nuclear and cytoplasmic expressions of ERβ1 and ERβ2 are predictive of response to therapy and alters prognosis in familial breast cancers

(2010) Max Yan et al.   BREAST CANCER RESEARCH AND TREATMENT

Estrogen Receptor β1 Expression Is Regulated by miR-92 in Breast Cancer

(2010) Hakeemah Al-Nakhle et al.   CANCER RESEARCH

Genome-Wide Mapping of Estrogen Receptor-β–Binding Regions Reveals Extensive Cross-Talk with Transcription Factor Activator Protein-1

(2010) Chunyan Zhao et al.   CANCER RESEARCH

Estrogen receptor β2 and β5 are associated with poor prognosis in prostate cancer, and promote cancer cell migration and invasion

(2010) Yuet-Kin Leung et al.   ENDOCRINE-RELATED CANCER

Steroid profiles in ovarian follicular fluid in women with and without polycystic ovary syndrome, analyzed by liquid chromatography-tandem mass spectrometry

(2010) Tord Naessen et al.   FERTILITY AND STERILITY

Estrogen Receptor β Binds to and Regulates Three Distinct Classes of Target Genes

(2010) Omar I. Vivar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oestrogen receptor splice variants in the pathogenesis of disease

(2009) Siân E. Taylor et al.   CANCER LETTERS

Differential regulation of oestrogen receptor β isoforms by 5′ untranslated regions in cancer

(2009) Laura Smith et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The importance of ERβ signalling in the ovary

(2009) Ann E Drummond et al.   JOURNAL OF ENDOCRINOLOGY

Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary

(2009) Sohrab P. Shah et al.   NEW ENGLAND JOURNAL OF MEDICINE

Loss of estrogen receptor β isoform expression and its correlation with aberrant DNA methylation of the 5′-untranslated region in human epithelial ovarian carcinoma

(2008) Fumihiko Suzuki et al.   CANCER SCIENCE

Nuclear and Cytoplasmic Expression of ER 1, ER 2, and ER 5 Identifies Distinct Prognostic Outcome for Breast Cancer Patients

(2008) A. M. Shaaban et al.   CLINICAL CANCER RESEARCH

Follicle dynamics and anovulation in polycystic ovary syndrome

(2008) S. Franks et al.   HUMAN REPRODUCTION UPDATE

Granulosa Cell Tumor of the Ovary: Tumor Review

(2008) Georgios V. Koukourakis et al.   INTEGRATIVE CANCER THERAPIES

Anti-Mullerian Hormone, Its Receptor, FSH Receptor, and Androgen Receptor Genes Are Overexpressed by Granulosa Cells from Stimulated Follicles in Women with Polycystic Ovary Syndrome

(2008) Sophie Catteau-Jonard et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Aromatase is phosphorylated in situ at serine-118

(2008) Todd W. Miller et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Estrogen Receptors α and β as Determinants of Gene Expression: Influence of Ligand, Dose, and Chromatin Binding

(2008) Edmund C. Chang et al.   MOLECULAR ENDOCRINOLOGY

Expression and regulation of oestrogen receptors in the human corpus luteum

(2008) S. van den Driesche et al.   REPRODUCTION

Granulosa Cell Survival and Proliferation Are Altered in Polycystic Ovary Syndrome

(2007) M. Das et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM