Circulating ACE2 activity predicts mortality and disease severity in hospitalized COVID-19 patients

Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences

(2021) Sheila K. Patel et al.   EUROPEAN RESPIRATORY JOURNAL

Circulating Levels of Tissue Plasminogen Activator and Plasminogen Activator Inhibitor-1 Are Independent Predictors of Coronavirus Disease 2019 Severity: A Prospective, Observational Study

(2021) Brandon Michael Henry et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Level of the SARS-CoV-2 receptor ACE2 activity is highly elevated in old-aged patients with aortic stenosis: implications for ACE2 as a biomarker for the severity of COVID-19

(2021) Miklós Fagyas et al.   GeroScience

Angiotensin-Converting Enzyme 2 (ACE2) Elevation in Severe COVID-19

(2021) Roman Reindl-Schwaighofer et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Complement Overactivation and Consumption Predicts In-Hospital Mortality in SARS-CoV-2 Infection

(2021) György Sinkovits et al.   Frontiers in Immunology

Soluble angiotensin‐converting enzyme 2 is transiently elevated in COVID‐19 and correlates with specific inflammatory and endothelial markers

(2021) Annika Lundström et al.   JOURNAL OF MEDICAL VIROLOGY

Persistently Increased Systemic ACE2 Activity Is Associated With an Increased Inflammatory Response in Smokers With COVID-19

(2021) Gagandeep Kaur et al.   Frontiers in Physiology

Which ones, when and why should renin-angiotensin system inhibitors work against COVID-19?

(2021) Mariele Montanari et al.   Advances in Biological Regulation

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System

(2020) Mahmoud Gheblawi et al.   CIRCULATION RESEARCH

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysis

(2020) Giuseppe Lippi et al.   CLINICA CHIMICA ACTA

Severe immune thrombocytopenia in a critically ill COVID-19 patient

(2020) Ziga Martincic et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Severe COVID-19 infection associated with endothelial activation

(2020) Robert Escher et al.   THROMBOSIS RESEARCH

A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm

(2020) Michael R Garvin et al.   eLife

Serum ACE-2, angiotensin II, and aldosterone levels are unchanged in patients with COVID-19

(2020) Marina Rieder et al.   AMERICAN JOURNAL OF HYPERTENSION

Angiotensin-converting enzyme 2 (ACE2) levels in relation to risk factors for COVID-19 in two large cohorts of patients with atrial fibrillation

(2020) Lars Wallentin et al.   EUROPEAN HEART JOURNAL

Clinical, laboratory and radiological characteristics and outcomes of novel coronavirus (SARS-CoV-2) infection in humans: A systematic review and series of meta-analyses

(2020) Israel Júnior Borges do Nascimento et al.   PLoS One

A dramatic rise in serum ACE2 activity in a critically ill COVID-19 patient

(2020) Béla Nagy et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Counter-regulatory renin–angiotensin system in cardiovascular disease

(2019) Maria Paz Ocaranza et al.   Nature Reviews Cardiology

Circulating ACE2 activity correlates with cardiovascular disease development

(2016) K. Uri et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

New Perspectives in the Renin-Angiotensin-Aldosterone System (RAAS) IV: Circulating ACE2 as a Biomarker of Systolic Dysfunction in Human Hypertension and Heart Failure

(2014) Katalin Úri et al.   PLoS One