Antitumor Effects of Ir(III)-2H-Indazole Complexes for Triple Negative Breast Cancer

Easily Available, Amphiphilic Diiron Cyclopentadienyl Complexes Exhibit in Vitro Anticancer Activity in 2D and 3D Human Cancer Cells through Redox Modulation Triggered by CO Release

(2021) Lorenzo Biancalana et al.   CHEMISTRY-A EUROPEAN JOURNAL

Interaction between DNA, Albumin and Apo-Transferrin and Iridium(III) Complexes with Phosphines Derived from Fluoroquinolones as a Potent Anticancer Drug

(2021) Sandra Amanda Kozieł et al.   Pharmaceuticals

Anticancer Cyclometalated Iridium(III) Complexes with Planar Ligands: Mitochondrial DNA Damage and Metabolism Disturbance

(2019) Jian-Jun Cao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Reactive Oxygen Species (ROS)-Based Nanomedicine

(2019) Bowen Yang et al.   CHEMICAL REVIEWS

Studies of anticancer activity in vitro and in vivo of iridium(III) polypyridyl complexes-loaded liposomes as drug delivery system

(2019) Wen-Yao Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Triple negative breast cancer and platinum-based systemic treatment: a meta-analysis and systematic review

(2019) Jessa Gilda P. Pandy et al.   BMC CANCER

Potential anticancer agent for selective damage to mitochondria or lysosomes: Naphthalimide-modified fluorescent biomarker half-sandwich iridium (III) and ruthenium (II) complexes

(2019) Wenli Ma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy

(2018) Guan-Jun Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Triple negative breast cancer: Emerging therapeutic modalities and novel combination therapies

(2018) Alice Lee et al.   CANCER TREATMENT REVIEWS

The side effects of platinum-based chemotherapy drugs: a review for chemists

(2018) Rabbab Oun et al.   DALTON TRANSACTIONS

An iridium (III) complex as potent anticancer agent induces apoptosis and autophagy in B16 cells through inhibition of the AKT/mTOR pathway

(2018) Bing Tang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Ru(II) Compounds: Next-Generation Anticancer Metallotherapeutics?

(2018) Sreekanth Thota et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pharmaco-genomic investigations of organo-iridium anticancer complexes reveal novel mechanism of action

(2018) Jessica M. Hearn et al.   Metallomics

Triple action Pt(iv) derivatives of cisplatin: a new class of potent anticancer agents that overcome resistance

(2018) Emanuele Petruzzella et al.   Chemical Science

Iridium (III) complex-loaded liposomes as a drug delivery system for lung cancer through mitochondrial dysfunction

(2018) Cancheng Liao et al.   International Journal of Nanomedicine

Assembly of Fully Substituted 2H -Indazoles Catalyzed by Cu2 O Rhombic Dodecahedra and Evaluation of Anticancer Activity

(2018) Rajeeva Lochana Panchangam et al.   ChemMedChem

Half-Sandwich Iridium and Ruthenium Complexes: Effective Tracking in Cells and Anticancer Studies

(2018) JuanJuan Li et al.   INORGANIC CHEMISTRY

Cyclometalated iridium(III)-guanidinium complexes as mitochondria-targeted anticancer agents

(2017) Xing-Dong Song et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Indazole-Based Covalent Inhibitors To Target Drug-Resistant Epidermal Growth Factor Receptor

(2017) Stefano Tomassi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Endoplasmic Reticulum-Localized Iridium(III) Complexes as Efficient Photodynamic Therapy Agents via Protein Modifications

(2016) Jung Seung Nam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interstitial Release of Cisplatin from Triggerable Liposomes Enhances Efficacy against Triple Negative Breast Cancer Solid Tumor Analogues

(2016) Sally Stras et al.   MOLECULAR PHARMACEUTICS

Pt(iv) derivatives of cisplatin and oxaliplatin with phenylbutyrate axial ligands are potent cytotoxic agents that act by several mechanisms of action

(2016) Raji Raveendran et al.   Chemical Science

Ester-Modified Cyclometalated Iridium(III) Complexes as Mitochondria-Targeting Anticancer Agents

(2016) Fang-Xin Wang et al.   Scientific Reports

Modulating the Anticancer Activity of Ruthenium(II)–Arene Complexes

(2015) Catherine M. Clavel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Lipid Nanocarriers of a Lipid-Conjugated Estrogenic Derivative Inhibit Tumor Growth and Enhance Cisplatin Activity against Triple-Negative Breast Cancer: Pharmacokinetic and Efficacy Evaluation

(2015) Terrick Andey et al.   MOLECULAR PHARMACEUTICS

CFAssay: statistical analysis of the colony formation assay

(2015) Herbert Braselmann et al.   Radiation Oncology

Organoiridium Complexes: Anticancer Agents and Catalysts

(2014) Zhe Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Theranostic Iridium(III) Complexes as One- and Two-Photon Phosphorescent Trackers to Monitor Autophagic Lysosomes

(2014) Liang He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

On the antitumor properties of novel cyclometalated benzimidazole Ru(ii), Ir(iii) and Rh(iii) complexes

(2013) Gorakh S. Yellol et al.   CHEMICAL COMMUNICATIONS

Membrane Localized Iridium(III) Complex Induces Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptosis in Human Cancer Cells

(2013) Rui Cao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

(2011) Jean-Claude Martinou et al.   DEVELOPMENTAL CELL

Iridium Complex with Antiangiogenic Properties

(2010) Alexander Wilbuer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Executioner caspase-3 and caspase-7 are functionally distinct proteases

(2008) J. G. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA