H. pylori CagA activates the NLRP3 inflammasome to promote gastric cancer cell migration and invasion

An update on the regulatory mechanisms of NLRP3 inflammasome activation

(2021) Seungwha Paik et al.   Cellular & Molecular Immunology

Inhibiting the NLRP3 Inflammasome

(2020) Lina Y. El-Sharkawy et al.   MOLECULES

NLRP3 promotes tumor growth and metastasis in human oral squamous cell carcinoma

(2018) Han Wang et al.   BMC CANCER

The NLRP3 inflammasome: Role in metabolic disorders and regulation by metabolic pathways

(2018) Danlu Jiang et al.   CANCER LETTERS

Intramolecular energies of the cytotoxic protein CagA of Helicobacter pylori as a possible descriptor of strains’ pathogenicity level

(2018) Diana F. Rojas-Rengifo et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Nanoparticle binding attenuates the pathobiology of gastric cancer-associated Helicobacter pylori

(2018) Dana Westmeier et al.   Nanoscale

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

(2017) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Helicobacter pylori controls NLRP3 expression by regulating hsa-miR-223-3p and IL-10 in cultured and primary human immune cells

(2017) Suneesh Kumar Pachathundikandi et al.   Innate Immunity

NLRP3 inflammasome: Its regulation and involvement in atherosclerosis

(2017) Zahra Hoseini et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Systematic analysis of phosphotyrosine antibodies recognizing single phosphorylated EPIYA-motifs in CagA of East Asian-type Helicobacter pylori strains

(2016) Judith Lind et al.   BMC MICROBIOLOGY

Pathobiology of Helicobacter pylori–Induced Gastric Cancer

(2016) Manuel Amieva et al.   GASTROENTEROLOGY

Helicobacter pylori CagA induces tumor suppressor gene hypermethylation by upregulating DNMT1 via AKT-NFκB pathway in gastric cancer development

(2016) Bao-gui Zhang et al.   Oncotarget

Global burden of cancers attributable to infections in 2012: a synthetic analysis

(2016) Martyn Plummer et al.   Lancet Global Health

Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?

(2015) Justine M. Abais et al.   ANTIOXIDANTS & REDOX SIGNALING

Chemodetection and Destruction of Host Urea Allows Helicobacter pylori to Locate the Epithelium

(2015) Julie Y. Huang et al.   Cell Host & Microbe

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

(2015) Amna Abderrazak et al.   Redox Biology

Helicobacter pylori in gastric carcinogenesis

(2015) Hyo Jun Ahn et al.   World Journal of Gastrointestinal Oncology

Helicobacter pylori CagA and Gastric Cancer: A Paradigm for Hit-and-Run Carcinogenesis

(2014) Masanori Hatakeyama   Cell Host & Microbe

Helicobacter pyloriInduces Cell Migration and Invasion Through Casein Kinase 2 in Gastric Epithelial Cells

(2014) Yeo Song Lee et al.   HELICOBACTER

Helicobacter pylori–Induced IL-1β Secretion in Innate Immune Cells Is Regulated by the NLRP3 Inflammasome and Requires the Cag Pathogenicity Island

(2014) Raphaela P. Semper et al.   JOURNAL OF IMMUNOLOGY

Helicobacter pylori-induced gastric inflammation and gastric cancer

(2013) Fei Wang et al.   CANCER LETTERS

The Cag pathogenicity island and interaction between TLR2/NOD2 and NLRP3 regulate IL-1β production inHelicobacter pyloriinfected dendritic cells

(2013) Dong-Jae Kim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Helicobacter pylori Genotyping from American Indigenous Groups Shows Novel Amerindian vacA and cagA Alleles and Asian, African and European Admixture

(2011) Margarita Camorlinga-Ponce et al.   PLoS One

Helicobacter pylori typing as a tool for tracking human migration

(2009) Y. Yamaoka   CLINICAL MICROBIOLOGY AND INFECTION

Helicobacter pylori virulence factors in gastric carcinogenesis

(2008) Sicheng Wen et al.   CANCER LETTERS

Regulation of Gastric Carcinogenesis by Helicobacter pylori Virulence Factors

(2008) A. T. Franco et al.   CANCER RESEARCH