MicroRNA-15a/16-1 Prevents Hepatocellular Carcinoma by Disrupting the Communication Between Kupffer Cells and Regulatory T Cells

Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations

(2020) Masashi Fujita et al.   EBioMedicine

ICOS+ Tregs: A Functional Subset of Tregs in Immune Diseases

(2020) Dan-Yang Li et al.   Frontiers in Immunology

CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes

(2019) Moritz Rapp et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Macrophage-derived CCL22 promotes an immunosuppressive tumor microenvironment via IL-8 in malignant pleural effusion

(2019) Dong Wang et al.   CANCER LETTERS

Immunotherapy in hepatocellular carcinoma

(2019) Luigi Buonaguro et al.   Annals of Hepatology

Current perspectives on the immunosuppressive tumor microenvironment in hepatocellular carcinoma: challenges and opportunities

(2019) Chen Lu et al.   Molecular Cancer

Immunotherapy for hepatocellular carcinoma

(2019) Yin Zongyi et al.   CANCER LETTERS

Diagnosis, Staging and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases

(2018) Jorge A. Marrero et al.   HEPATOLOGY

CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens

(2018) Jean-Paul Concordet et al.   NUCLEIC ACIDS RESEARCH

The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets

(2017) Bertrand Allard et al.   IMMUNOLOGICAL REVIEWS

EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection

(2017) Pietro Lampertico et al.   JOURNAL OF HEPATOLOGY

Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial

(2017) Anthony B El-Khoueiry et al.   LANCET

NFKB1: a suppressor of inflammation, ageing and cancer

(2016) Tyrell Cartwright et al.   FEBS Journal

Chemokine (C-C motif) receptor 2-positive monocytes aggravate the early phase of acetaminophen-induced acute liver injury

(2016) Jana C. Mossanen et al.   HEPATOLOGY

Fucoidan inhibits CCL22 production through NF-κB pathway in M2 macrophages: a potential therapeutic strategy for cancer

(2016) Jia Sun et al.   Scientific Reports

Immunological landscape and immunotherapy of hepatocellular carcinoma

(2015) Jesús Prieto et al.   Nature Reviews Gastroenterology & Hepatology

Distinct anti-oncogenic effect of various microRNAs in different mouse models of liver cancer

(2015) Junyan Tao et al.   Oncotarget

Dysfunctional CD39POSregulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis

(2013) Charlotte R. Grant et al.   HEPATOLOGY

A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C

(2013) Bruno Sangro et al.   JOURNAL OF HEPATOLOGY

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

(2013) Jun-Hao Li et al.   NUCLEIC ACIDS RESEARCH

Role of c-MYC in tumor-associated macrophages and cancer progression

(2013) Oscar M. Pello et al.   OncoImmunology

ICOS-Dependent Homeostasis and Function of Foxp3+ Regulatory T Cells in Islets of Nonobese Diabetic Mice

(2012) M. Kornete et al.   JOURNAL OF IMMUNOLOGY

Regulation of innate CD8+ T-cell activation mediated by cytokines

(2012) B. E. Freeman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2,

(2011) Coral Ho et al.   HEPATOLOGY

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

T regulatory cells control T-cell proliferation partly by the release of soluble CD25 in patients with B-cell malignancies

(2010) Camilla A. Lindqvist et al.   IMMUNOLOGY

Characterization of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice

(2010) Manabu Kinoshita et al.   JOURNAL OF HEPATOLOGY

NF-κB as a central regulator of macrophage function in tumors

(2010) Subhra K. Biswas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Hepatocellular carcinoma: a global view

(2010) Ju Dong Yang et al.   Nature Reviews Gastroenterology & Hepatology

miR-15a and miR-16-1 in cancer: discovery, function and future perspectives

(2009) R I Aqeilan et al.   CELL DEATH AND DIFFERENTIATION

Regulatory T cells: how do they suppress immune responses?

(2009) S. Sakaguchi et al.   INTERNATIONAL IMMUNOLOGY

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor  B

(2009) C. Porta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA