NFKB1: a suppressor of inflammation, ageing and cancer

Loss of Nfkb1 leads to early onset aging

(2016) Giovanna M. Bernal et al.   Aging-US

KPC1-Mediated Ubiquitination and Proteasomal Processing of NF-κB1 p105 to p50 Restricts Tumor Growth

(2015) Yelena Kravtsova-Ivantsiv et al.   CELL

S-phase-dependent p50/NF-кB1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability

(2015) Clayton D Crawley et al.   CELL CYCLE

NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma

(2015) C. L. Wilson et al.   Nature Communications

IκBβ enhances the generation of the low-affinity NFκB/RelA homodimer

(2015) Rachel Tsui et al.   Nature Communications

Inhibition of Transcription by B Cell Leukemia 3 (Bcl-3) Protein Requires Interaction with Nuclear Factor κB (NF-κB) p50

(2014) Patricia E. Collins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor

(2014) D J Voce et al.   ONCOGENE

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice

(2014) Diana Jurk et al.   Nature Communications

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome

(2013) Yangyang Bian et al.   Journal of Proteomics

Complex regulation of acute and chronic neuroinflammatory responses in mouse models deficient for nuclear factor kappa B p50 subunit

(2013) Taisia Rolova et al.   NEUROBIOLOGY OF DISEASE

Tumor progression locus 2/Cot is required for activation of extracellular regulated kinase in liver injury and toll-like receptor-induced TIMP-1 gene transcription in hepatic stellate cells in mice

(2012) Maria J. Perugorria et al.   HEPATOLOGY

NF-κB and the link between inflammation and cancer

(2012) Joseph A. DiDonato et al.   IMMUNOLOGICAL REVIEWS

EHMT1 Protein Binds to Nuclear Factor-κB p50 and Represses Gene Expression

(2012) Chee-Kwee Ea et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordinate Regulation of TPL-2 and NF- B Signaling in Macrophages by NF- B1 p105

(2012) H.-T. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-κB p50 and a single nucleotide in the κB-site

(2012) Clayton D. Crawley et al.   NUCLEIC ACIDS RESEARCH

C/EBP  and C/EBP  oncoproteins regulate nfkb1 and displace histone deacetylases from NF- B p50 homodimers to induce NF- B target genes

(2011) I. Paz-Priel et al.   BLOOD

p50 (NF-κB1) Is an Effector Protein in the Cytotoxic Response to DNA Methylation Damage

(2011) Adam M. Schmitt et al.   MOLECULAR CELL

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

BAG-1 interacts with the p50–p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis

(2011) S L Southern et al.   ONCOGENE

The Specificity of Innate Immune Responses Is Enforced by Repression of Interferon Response Elements by NF- B p50

(2011) C. S. Cheng et al.   Science Signaling

The NF-κB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes

(2010) Ahmed M. Elsharkawy et al.   JOURNAL OF HEPATOLOGY

NF-κB1 contributes to T cell-mediated control of Toxoplasma gondii in the CNS

(2010) Tajie H. Harris et al.   JOURNAL OF NEUROIMMUNOLOGY

NF- B p50 Regulates C/EBP  Expression and Inflammatory Cytokine-Induced Neutrophil Production

(2009) D. Wang et al.   JOURNAL OF IMMUNOLOGY

NF- B1 p105 Regulates T Cell Homeostasis and Prevents Chronic Inflammation

(2009) M. Chang et al.   JOURNAL OF IMMUNOLOGY

The Nfkb1 and Nfkb2 Proteins p105 and p100 Function as the Core of High-Molecular-Weight Heterogeneous Complexes

(2009) Olga V. Savinova et al.   MOLECULAR CELL

Quantitative Phosphoproteomic Analysis of T Cell Receptor Signaling Reveals System-Wide Modulation of Protein-Protein Interactions

(2009) V. Mayya et al.   Science Signaling

The Nuclear IκB Protein IκBζ Specifically Binds NF-κB p50 Homodimers and Forms a Ternary Complex on κB DNA

(2008) Dan V. Trinh et al.   JOURNAL OF MOLECULAR BIOLOGY

Proteolysis of NF-κB1 p105 is essential for T cell antigen receptor–induced proliferation

(2008) Srividya Sriskantharajah et al.   NATURE IMMUNOLOGY