Efficacy of chloroquine and hydroxychloroquine for the treatment of hospitalized COVID-19 patients: a meta-analysis
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Efficacy of chloroquine and hydroxychloroquine for the treatment of hospitalized COVID-19 patients: a meta-analysis
Authors
Keywords
-
Journal
Future Virology
Volume 17, Issue 2, Pages 95-118
Publisher
Future Medicine Ltd
Online
2021-12-03
DOI
10.2217/fvl-2021-0119
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Effect of hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial, an update with an intention-to-treat analysis and clinical outcomes
- (2021) Philippe Gautret et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- The efficacy and safety of hydroxychloroquine for COVID-19 prophylaxis: A systematic review and meta-analysis of randomized trials
- (2021) Kimberley Lewis et al. PLoS One
- Covid-19: US cases surge but vaccine distribution is slow
- (2021) Janice Hopkins Tanne BMJ-British Medical Journal
- The Efficacy and Safety of Hydroxychloroquine in Patients with COVID-19: A Multicenter National Retrospective Cohort
- (2021) Abdulkarim Abdulrahman et al. Infectious Diseases and Therapy
- Impact of hydroxychloroquine on disease progression and ICU admissions in patients with SARS-CoV-2 infection
- (2021) Nirvana Awad et al. AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
- COVID-19 fatality rates in hospitalized patients: systematic review and meta-analysis
- (2021) Ana Macedo et al. ANNALS OF EPIDEMIOLOGY
- Hydroxychloroquine with azithromycin in patients hospitalized for mild and moderate COVID-19
- (2021) Elisa Baranski Lamback et al. Brazilian Journal of Infectious Diseases
- No clinical benefit in mortality associated with hydroxychloroquine treatment in patients with COVID-19
- (2021) Kenneth Sands et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Urgent needs of low-income and middle-income countries for COVID-19 vaccines and therapeutics
- (2021) J Peter Figueroa et al. LANCET
- Examination of patient characteristics and hydroxychloroquine use based on the US Food and Drug Administration’s recommendation: a cross-sectional analysis in New York
- (2021) Eun Ji Kim et al. BMJ Open
- Both Chloroquine and Lopinavir/Ritonavir Are Ineffective for COVID-19 Treatment and Combined Worsen the Pathology: A Single-Center Experience with Severely Ill Patients
- (2021) Fernando Sevilla-Castillo et al. Biomed Research International
- COVID-19 Vaccine Hesitancy Worldwide: A Concise Systematic Review of Vaccine Acceptance Rates
- (2021) Malik Sallam Vaccines
- Arrhythmias in Patients With Coronavirus Disease 2019 Treated With Hydroxychloroquine and/or Azithromycin
- (2021) Urvashi Hooda et al. AMERICAN JOURNAL OF THERAPEUTICS
- Hydroxychloroquine in mild-to-moderate COVID-19: a placebo-controlled double blind trial
- (2021) Vincent Dubée et al. CLINICAL MICROBIOLOGY AND INFECTION
- COVID-19 Evidence Accelerator: A parallel analysis to describe the use of Hydroxychloroquine with or without Azithromycin among hospitalized COVID-19 patients
- (2021) Mark Stewart et al. PLoS One
- Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials
- (2021) Cathrine Axfors et al. Nature Communications
- Covid-19: AstraZeneca vaccine prevents 79% of symptomatic disease and 100% of severe disease, US study finds
- (2021) Shaun Griffin BMJ-British Medical Journal
- The PRISMA 2020 statement: an updated guideline for reporting systematic reviews
- (2021) Matthew J Page et al. BMJ-British Medical Journal
- Clinical Efficacy of Hydroxychloroquine in Patients with COVID-19: Findings from an Observational Comparative Study in Saudi Arabia
- (2021) Saleh Alghamdi et al. Antibiotics-Basel
- Efficacy and Safety of Hydroxychloroquine for Hospitalized COVID-19 Patients: A Systematic Review and Meta-Analysis
- (2021) Adrian V. Hernandez et al. Journal of Clinical Medicine
- Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology
- (2020) Eva Schrezenmeier et al. Nature Reviews Rheumatology
- A Rush to Judgment? Rapid Reporting and Dissemination of Results and Its Consequences Regarding the Use of Hydroxychloroquine for COVID-19
- (2020) Alfred H.J. Kim et al. ANNALS OF INTERNAL MEDICINE
- In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
- (2020) Xueting Yao et al. CLINICAL INFECTIOUS DISEASES
- QT Interval Prolongation and Torsade De Pointes in Patients with COVID-19 treated with Hydroxychloroquine/Azithromycin
- (2020) Ehud Chorin et al. HEART RHYTHM
- QT prolongation, torsades de pointes, and sudden death with short courses of chloroquine or hydroxychloroquine as used in COVID-19: A systematic review
- (2020) Lior Jankelson et al. HEART RHYTHM
- A review on possible modes of actions of Chloroquine/ Hydroxychloroquine: Repurposing against SAR-COV-2 (COVID 19) pandemic
- (2020) Satyajit Tripathy et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
- (2020) Philippe Gautret et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State
- (2020) Eli S. Rosenberg et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Efficacy of therapeutic plasma exchange for treatment of autoimmune hemolytic anemia: A systematic review and meta‐analysis of randomized controlled trials
- (2020) Jiawen Deng et al. JOURNAL OF CLINICAL APHERESIS
- Does hydroxychloroquine combat COVID-19? A timeline of evidence
- (2020) Erisa Alia et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- The QT interval in patients with COVID-19 treated with hydroxychloroquine and azithromycin
- (2020) Ehud Chorin et al. NATURE MEDICINE
- Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19
- (2020) Joshua Geleris et al. NEW ENGLAND JOURNAL OF MEDICINE
- Hydroxychloroquine and covid-19
- (2020) Neeraj Sinha et al. POSTGRADUATE MEDICAL JOURNAL
- Low dose of hydroxychloroquine reduces fatality of critically ill patients with COVID-19
- (2020) Bo Yu et al. Science China-Life Sciences
- Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies
- (2020) Jianjun Gao et al. BioScience Trends
- Chloroquine-induced QTc prolongation in COVID-19 patients
- (2020) M. P. H. van den Broek et al. Netherlands Heart Journal
- Therapeutic use of chloroquine and hydroxychloroquine in COVID-19 and other viral infections: A narrative review
- (2020) Anwar M. Hashem et al. Travel Medicine and Infectious Disease
- Covid-19: six million doses of hydroxychloroquine donated to US despite lack of evidence
- (2020) Elisabeth Mahase BMJ-British Medical Journal
- Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial
- (2020) Wei Tang et al. BMJ-British Medical Journal
- Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data
- (2020) Matthieu Mahévas et al. BMJ-British Medical Journal
- Lack of viral clearance by the combination of hydroxychloroquine and azithromycin or lopinavir and ritonavir in SARS-CoV-2-related acute respiratory distress syndrome
- (2020) Sami Hraiech et al. Annals of Intensive Care
- Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19
- (2020) Mingxing Huang et al. National Science Review
- Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
- (2020) Jia Liu et al. Cell Discovery
- A comprehensive review of COVID-19 characteristics
- (2020) Hanie Esakandari et al. BIOLOGICAL PROCEDURES ONLINE
- Clinical outcomes and adverse events in patients hospitalised with COVID‐19, treated with off‐label hydroxychloroquine and azithromycin
- (2020) Mary Kelly et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- COVID-19 and Misinformation: How an Infodemic Fueled the prominence of Vitamin D
- (2020) Joshua Henrina et al. BRITISH JOURNAL OF NUTRITION
- Compassionate use of hydroxychloroquine in clinical practice for patients with mild to severe Covid-19 in a French university hospital
- (2020) Olivier Paccoud et al. CLINICAL INFECTIOUS DISEASES
- QT Interval Prolongation Under Hydroxychloroquine/Azithromycin Association for Inpatients With SARS‐CoV‐2 Lower Respiratory Tract Infection
- (2020) Sok‐Sithikun Bun et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Fast news or fake news?
- (2020) Anthony King EMBO REPORTS
- Pathogenesis of COVID-19-induced ARDS: implications for an aging population
- (2020) Manuel A. Torres Acosta et al. EUROPEAN RESPIRATORY JOURNAL
- Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19
- (2020) Samia Arshad et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- A retrospective evaluation on the efficacy of Lopinavir/ritonavir and chloroquine to treat non-severe COVID-19 patients
- (2020) Guiju Gao et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- The effect of 5-day course of hydroxychloroquine and azithromycin combination on QT interval in non-ICU COVID19(+) patients
- (2020) Nijad Bakhshaliyev et al. JOURNAL OF ELECTROCARDIOLOGY
- QT prolongation in a diverse, urban population of COVID-19 patients treated with hydroxychloroquine, chloroquine, or azithromycin
- (2020) Brian C Hsia et al. JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
- Efficacy of hydroxychloroquine and tocilizumab in patients with COVID-19: A single-center retrospective chart review (Preprint)
- (2020) Sohaib Roomi et al. JOURNAL OF MEDICAL INTERNET RESEARCH
- Hydroxychloroquine treatment in COVID‐19: a descriptive observational analysis of 30 cases from a single center in Wuhan, China
- (2020) Huiying Xue et al. JOURNAL OF MEDICAL VIROLOGY
- Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19
- (2020) Alexandre B. Cavalcanti et al. NEW ENGLAND JOURNAL OF MEDICINE
- Hydroxychloroquine and tocilizumab therapy in COVID-19 patients—An observational study
- (2020) Andrew Ip et al. PLoS One
- Pharmacological prevention of fractures in patients undergoing glucocorticoid therapies: a systematic review and network meta-analysis
- (2020) Jiawen Deng et al. RHEUMATOLOGY
- Hydroxychloroquine versus lopinavir/ritonavir in severe COVID-19 patients
- (2020) Mario Karolyi et al. WIENER KLINISCHE WOCHENSCHRIFT
- Safe use of hydroxychloroquine and its combination with azithromycin in the context of Sars-CoV-2 outbreak: Clinical experience in a Belgian tertiary center
- (2020) Lucie Pothen et al. Travel Medicine and Infectious Disease
- Outcomes of 3,737 COVID-19 patients treated with hydroxychloroquine/azithromycin and other regimens in Marseille, France: A retrospective analysis
- (2020) Jean-Christophe Lagier et al. Travel Medicine and Infectious Disease
- Hydroxychloroquine use in Hospitalized Patients with COVID-19: An observational matched cohort study
- (2020) Markos Kalligeros et al. Journal of Global Antimicrobial Resistance
- Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
- (2020) Mayla Gabriela Silva Borba et al. JAMA Network Open
- Hydroxychloroquine in the Treatment of COVID-19: A Multicenter Randomized Controlled Study
- (2020) Sherief Abd-Elsalam et al. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
- 'Effect of hydroxychloroquine with or without azithromycin on the mortality of COVID-19 patients' – Author’s reply
- (2020) Thibault Fiolet et al. CLINICAL MICROBIOLOGY AND INFECTION
- Effect of Combination Therapy of Hydroxychloroquine and Azithromycin on Mortality in Patients With COVID‐19
- (2020) Marinella Lauriola et al. CTS-Clinical and Translational Science
- Use of hydroxychloroquine in hospitalised COVID-19 patients is associated with reduced mortality: Findings from the observational multicentre Italian CORIST study
- (2020) Augusto Di Castelnuovo et al. European Journal of Internal Medicine
- Predictive factors for cardiac conduction abnormalities with hydroxychloroquine-containing combinations for COVID-19
- (2020) Sergio Padilla et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Low-dose hydroxychloroquine therapy and mortality in hospitalised patients with COVID-19: a nationwide observational study of 8075 participants
- (2020) Lucy Catteau et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Assessing QT interval in COVID-19 patients:safety of hydroxychloroquine-azithromycin combination regimen
- (2020) Andrea Bernardini et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- QTc prolongation among hydroxychloroquine sulfate‐treated COVID‐19 patients: An observational study
- (2020) Bashar Fteiha et al. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
- Early Hydroxychloroquine but not Chloroquine use reduces ICU admission in COVID-19 patients
- (2020) A.J.J. Lammers et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Efficacy of chloroquine or hydroxychloroquine in COVID-19 patients: a systematic review and meta-analysis
- (2020) Zakariya Kashour et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- The Pandemic of Publications: Are We Sacrificing Quality for Quantity?
- (2020) Russell Seth Martins et al. MAYO CLINIC PROCEEDINGS
- Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19
- (2020) NEW ENGLAND JOURNAL OF MEDICINE
- Drug repurposing approach to fight COVID-19
- (2020) Thakur Uttam Singh et al. Pharmacological Reports
- Hydroxychloroquine in hospitalized COVID‐19 patients: Real world experience assessing mortality
- (2020) Frank H. Annie et al. PHARMACOTHERAPY
- Comparing the impact of Hydroxychloroquine based regimens and standard treatment on COVID-19 patient outcomes: A retrospective cohort study
- (2020) Saja H. Almazrou et al. SAUDI PHARMACEUTICAL JOURNAL
- Characteristics and outcomes of acute respiratory distress syndrome related to COVID-19 in Belgian and French intensive care units according to antiviral strategies: the COVADIS multicentre observational study
- (2020) David Grimaldi et al. Annals of Intensive Care
- Treating Covid-19 With Hydroxychloroquine (TEACH): A Multicenter, Double-Blind, Randomized Controlled Trial in Hospitalized Patients
- (2020) Robert J Ulrich et al. Open Forum Infectious Diseases
- Hydroxychloroquine/azithromycin treatment, QT interval and ventricular arrhythmias in hospitalised patients with COVID‐19
- (2020) İbrahim Halil Özdemir et al. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
- Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19
- (2020) Wesley H. Self et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Hydroxychloroquine is associated with slower viral clearance in clinical COVID-19 patients with mild to moderate disease
- (2020) Jihad Mallat et al. MEDICINE
- A multicenter, randomized, open-label, controlled trial to evaluate the efficacy and tolerability of hydroxychloroquine and a retrospective study in adult patients with mild to moderate coronavirus disease 2019 (COVID-19)
- (2020) Cheng-Pin Chen et al. PLoS One
- A systematic review and meta-analysis on chloroquine and hydroxychloroquine as monotherapy or combined with azithromycin in COVID-19 treatment
- (2020) Ramy Mohamed Ghazy et al. Scientific Reports
- Structural basis for human coronavirus attachment to sialic acid receptors
- (2019) M. Alejandra Tortorici et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RoB 2: a revised tool for assessing risk of bias in randomised trials
- (2019) Jonathan A C Sterne et al. BMJ-British Medical Journal
- Methods to systematically review and meta-analyse observational studies: a systematic scoping review of recommendations
- (2018) Monika Mueller et al. BMC Medical Research Methodology
- Host Lipid Rafts Play a Major Role in Binding and Endocytosis of Influenza A Virus
- (2018) Dileep Verma et al. Viruses-Basel
- Clinical Practice Guidelines
- (2017) M. Hassan Murad MAYO CLINIC PROCEEDINGS
- Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice
- (2017) Chunfeng Li et al. EBioMedicine
- Optimally estimating the sample mean from the sample size, median, mid-range, and/or mid-quartile range
- (2016) Dehui Luo et al. STATISTICAL METHODS IN MEDICAL RESEARCH
- Chloroquine, an Endocytosis Blocking Agent, Inhibits Zika Virus Infection in Different Cell Models
- (2016) Rodrigo Delvecchio et al. Viruses-Basel
- ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions
- (2016) Jonathan AC Sterne et al. BMJ-British Medical Journal
- ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions
- (2016) Jonathan AC Sterne et al. BMJ-British Medical Journal
- Chloroquine inhibited Ebola virus replication in vitro but failed to protect against infection and disease in the in vivo guinea pig model
- (2015) Stuart D. Dowall et al. JOURNAL OF GENERAL VIROLOGY
- Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range
- (2015) Xiang Wan et al. BMC Medical Research Methodology
- Macrolide Antibiotics and the Risk of Cardiac Arrhythmias
- (2014) Richard K. Albert et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture
- (2014) Adriaan H. de Wilde et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Systematic Screen of FDA-Approved Drugs for Inhibitors of Biological Threat Agents
- (2013) Peter B. Madrid et al. PLoS One
- Chloroquine Inhibits Dengue Virus Type 2 Replication in Vero Cells but Not in C6/36 Cells
- (2013) Kleber Juvenal Silva Farias et al. TheScientificWorldJOURNAL
- Effects of Hydroxychloroquine on Immune Activation and Disease Progression Among HIV-Infected Patients Not Receiving Antiretroviral Therapy
- (2012) Nicholas I. Paton et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Assessment of in vitro prophylactic and therapeutic efficacy of chloroquine against chikungunya virus in vero cells
- (2010) Mohsin Khan et al. JOURNAL OF MEDICAL VIROLOGY
- A Randomized Controlled Trial of Chloroquine for the Treatment of Dengue in Vietnamese Adults
- (2010) Vianney Tricou et al. PLoS Neglected Tropical Diseases
- Lipid rafts are involved in SARS-CoV entry into Vero E6 cells
- (2008) Yanning Lu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- On Chikungunya Acute Infection and Chloroquine Treatment
- (2008) Xavier De Lamballerie et al. VECTOR-BORNE AND ZOONOTIC DISEASES
- GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
- (2008) Gordon H Guyatt et al. BMJ-British Medical Journal
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started