Efficacy of chloroquine and hydroxychloroquine for the treatment of hospitalized COVID-19 patients: a meta-analysis

Effect of hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial, an update with an intention-to-treat analysis and clinical outcomes

(2021) Philippe Gautret et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

The efficacy and safety of hydroxychloroquine for COVID-19 prophylaxis: A systematic review and meta-analysis of randomized trials

(2021) Kimberley Lewis et al.   PLoS One

Covid-19: US cases surge but vaccine distribution is slow

(2021) Janice Hopkins Tanne   BMJ-British Medical Journal

The Efficacy and Safety of Hydroxychloroquine in Patients with COVID-19: A Multicenter National Retrospective Cohort

(2021) Abdulkarim Abdulrahman et al.   Infectious Diseases and Therapy

Impact of hydroxychloroquine on disease progression and ICU admissions in patients with SARS-CoV-2 infection

(2021) Nirvana Awad et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

COVID-19 fatality rates in hospitalized patients: systematic review and meta-analysis

(2021) Ana Macedo et al.   ANNALS OF EPIDEMIOLOGY

Hydroxychloroquine with azithromycin in patients hospitalized for mild and moderate COVID-19

(2021) Elisa Baranski Lamback et al.   Brazilian Journal of Infectious Diseases

No clinical benefit in mortality associated with hydroxychloroquine treatment in patients with COVID-19

(2021) Kenneth Sands et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Urgent needs of low-income and middle-income countries for COVID-19 vaccines and therapeutics

(2021) J Peter Figueroa et al.   LANCET

Examination of patient characteristics and hydroxychloroquine use based on the US Food and Drug Administration’s recommendation: a cross-sectional analysis in New York

(2021) Eun Ji Kim et al.   BMJ Open

Both Chloroquine and Lopinavir/Ritonavir Are Ineffective for COVID-19 Treatment and Combined Worsen the Pathology: A Single-Center Experience with Severely Ill Patients

(2021) Fernando Sevilla-Castillo et al.   Biomed Research International

COVID-19 Vaccine Hesitancy Worldwide: A Concise Systematic Review of Vaccine Acceptance Rates

(2021) Malik Sallam   Vaccines

Arrhythmias in Patients With Coronavirus Disease 2019 Treated With Hydroxychloroquine and/or Azithromycin

(2021) Urvashi Hooda et al.   AMERICAN JOURNAL OF THERAPEUTICS

Hydroxychloroquine in mild-to-moderate COVID-19: a placebo-controlled double blind trial

(2021) Vincent Dubée et al.   CLINICAL MICROBIOLOGY AND INFECTION

COVID-19 Evidence Accelerator: A parallel analysis to describe the use of Hydroxychloroquine with or without Azithromycin among hospitalized COVID-19 patients

(2021) Mark Stewart et al.   PLoS One

Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials

(2021) Cathrine Axfors et al.   Nature Communications

Covid-19: AstraZeneca vaccine prevents 79% of symptomatic disease and 100% of severe disease, US study finds

(2021) Shaun Griffin   BMJ-British Medical Journal

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

(2021) Matthew J Page et al.   BMJ-British Medical Journal

Clinical Efficacy of Hydroxychloroquine in Patients with COVID-19: Findings from an Observational Comparative Study in Saudi Arabia

(2021) Saleh Alghamdi et al.   Antibiotics-Basel

Efficacy and Safety of Hydroxychloroquine for Hospitalized COVID-19 Patients: A Systematic Review and Meta-Analysis

(2021) Adrian V. Hernandez et al.   Journal of Clinical Medicine

Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology

(2020) Eva Schrezenmeier et al.   Nature Reviews Rheumatology

A Rush to Judgment? Rapid Reporting and Dissemination of Results and Its Consequences Regarding the Use of Hydroxychloroquine for COVID-19

(2020) Alfred H.J. Kim et al.   ANNALS OF INTERNAL MEDICINE

In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

(2020) Xueting Yao et al.   CLINICAL INFECTIOUS DISEASES

QT Interval Prolongation and Torsade De Pointes in Patients with COVID-19 treated with Hydroxychloroquine/Azithromycin

(2020) Ehud Chorin et al.   HEART RHYTHM

QT prolongation, torsades de pointes, and sudden death with short courses of chloroquine or hydroxychloroquine as used in COVID-19: A systematic review

(2020) Lior Jankelson et al.   HEART RHYTHM

A review on possible modes of actions of Chloroquine/ Hydroxychloroquine: Repurposing against SAR-COV-2 (COVID 19) pandemic

(2020) Satyajit Tripathy et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial

(2020) Philippe Gautret et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State

(2020) Eli S. Rosenberg et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Efficacy of therapeutic plasma exchange for treatment of autoimmune hemolytic anemia: A systematic review and meta‐analysis of randomized controlled trials

(2020) Jiawen Deng et al.   JOURNAL OF CLINICAL APHERESIS

Does hydroxychloroquine combat COVID-19? A timeline of evidence

(2020) Erisa Alia et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

The QT interval in patients with COVID-19 treated with hydroxychloroquine and azithromycin

(2020) Ehud Chorin et al.   NATURE MEDICINE

Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19

(2020) Joshua Geleris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hydroxychloroquine and covid-19

(2020) Neeraj Sinha et al.   POSTGRADUATE MEDICAL JOURNAL

Low dose of hydroxychloroquine reduces fatality of critically ill patients with COVID-19

(2020) Bo Yu et al.   Science China-Life Sciences

Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies

(2020) Jianjun Gao et al.   BioScience Trends

Chloroquine-induced QTc prolongation in COVID-19 patients

(2020) M. P. H. van den Broek et al.   Netherlands Heart Journal

Therapeutic use of chloroquine and hydroxychloroquine in COVID-19 and other viral infections: A narrative review

(2020) Anwar M. Hashem et al.   Travel Medicine and Infectious Disease

Covid-19: six million doses of hydroxychloroquine donated to US despite lack of evidence

(2020) Elisabeth Mahase   BMJ-British Medical Journal

Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial

(2020) Wei Tang et al.   BMJ-British Medical Journal

Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data

(2020) Matthieu Mahévas et al.   BMJ-British Medical Journal

Lack of viral clearance by the combination of hydroxychloroquine and azithromycin or lopinavir and ritonavir in SARS-CoV-2-related acute respiratory distress syndrome

(2020) Sami Hraiech et al.   Annals of Intensive Care

Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19

(2020) Mingxing Huang et al.   National Science Review

Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro

(2020) Jia Liu et al.   Cell Discovery

A comprehensive review of COVID-19 characteristics

(2020) Hanie Esakandari et al.   BIOLOGICAL PROCEDURES ONLINE

Clinical outcomes and adverse events in patients hospitalised with COVID‐19, treated with off‐label hydroxychloroquine and azithromycin

(2020) Mary Kelly et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

COVID-19 and Misinformation: How an Infodemic Fueled the prominence of Vitamin D

(2020) Joshua Henrina et al.   BRITISH JOURNAL OF NUTRITION

Compassionate use of hydroxychloroquine in clinical practice for patients with mild to severe Covid-19 in a French university hospital

(2020) Olivier Paccoud et al.   CLINICAL INFECTIOUS DISEASES

QT Interval Prolongation Under Hydroxychloroquine/Azithromycin Association for Inpatients With SARS‐CoV‐2 Lower Respiratory Tract Infection

(2020) Sok‐Sithikun Bun et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Fast news or fake news?

(2020) Anthony King   EMBO REPORTS

Pathogenesis of COVID-19-induced ARDS: implications for an aging population

(2020) Manuel A. Torres Acosta et al.   EUROPEAN RESPIRATORY JOURNAL

Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19

(2020) Samia Arshad et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

A retrospective evaluation on the efficacy of Lopinavir/ritonavir and chloroquine to treat non-severe COVID-19 patients

(2020) Guiju Gao et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

The effect of 5-day course of hydroxychloroquine and azithromycin combination on QT interval in non-ICU COVID19(+) patients

(2020) Nijad Bakhshaliyev et al.   JOURNAL OF ELECTROCARDIOLOGY

QT prolongation in a diverse, urban population of COVID-19 patients treated with hydroxychloroquine, chloroquine, or azithromycin

(2020) Brian C Hsia et al.   JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY

Efficacy of hydroxychloroquine and tocilizumab in patients with COVID-19: A single-center retrospective chart review (Preprint)

(2020) Sohaib Roomi et al.   JOURNAL OF MEDICAL INTERNET RESEARCH

Hydroxychloroquine treatment in COVID‐19: a descriptive observational analysis of 30 cases from a single center in Wuhan, China

(2020) Huiying Xue et al.   JOURNAL OF MEDICAL VIROLOGY

Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19

(2020) Alexandre B. Cavalcanti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hydroxychloroquine and tocilizumab therapy in COVID-19 patients—An observational study

(2020) Andrew Ip et al.   PLoS One

Pharmacological prevention of fractures in patients undergoing glucocorticoid therapies: a systematic review and network meta-analysis

(2020) Jiawen Deng et al.   RHEUMATOLOGY

Hydroxychloroquine versus lopinavir/ritonavir in severe COVID-19 patients

(2020) Mario Karolyi et al.   WIENER KLINISCHE WOCHENSCHRIFT

Safe use of hydroxychloroquine and its combination with azithromycin in the context of Sars-CoV-2 outbreak: Clinical experience in a Belgian tertiary center

(2020) Lucie Pothen et al.   Travel Medicine and Infectious Disease

Outcomes of 3,737 COVID-19 patients treated with hydroxychloroquine/azithromycin and other regimens in Marseille, France: A retrospective analysis

(2020) Jean-Christophe Lagier et al.   Travel Medicine and Infectious Disease

Hydroxychloroquine use in Hospitalized Patients with COVID-19: An observational matched cohort study

(2020) Markos Kalligeros et al.   Journal of Global Antimicrobial Resistance

Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection

(2020) Mayla Gabriela Silva Borba et al.   JAMA Network Open

Hydroxychloroquine in the Treatment of COVID-19: A Multicenter Randomized Controlled Study

(2020) Sherief Abd-Elsalam et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

'Effect of hydroxychloroquine with or without azithromycin on the mortality of COVID-19 patients' – Author’s reply

(2020) Thibault Fiolet et al.   CLINICAL MICROBIOLOGY AND INFECTION

Effect of Combination Therapy of Hydroxychloroquine and Azithromycin on Mortality in Patients With COVID‐19

(2020) Marinella Lauriola et al.   CTS-Clinical and Translational Science

Use of hydroxychloroquine in hospitalised COVID-19 patients is associated with reduced mortality: Findings from the observational multicentre Italian CORIST study

(2020) Augusto Di Castelnuovo et al.   European Journal of Internal Medicine

Predictive factors for cardiac conduction abnormalities with hydroxychloroquine-containing combinations for COVID-19

(2020) Sergio Padilla et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Low-dose hydroxychloroquine therapy and mortality in hospitalised patients with COVID-19: a nationwide observational study of 8075 participants

(2020) Lucy Catteau et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Assessing QT interval in COVID-19 patients:safety of hydroxychloroquine-azithromycin combination regimen

(2020) Andrea Bernardini et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

QTc prolongation among hydroxychloroquine sulfate‐treated COVID‐19 patients: An observational study

(2020) Bashar Fteiha et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Early Hydroxychloroquine but not Chloroquine use reduces ICU admission in COVID-19 patients

(2020) A.J.J. Lammers et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Efficacy of chloroquine or hydroxychloroquine in COVID-19 patients: a systematic review and meta-analysis

(2020) Zakariya Kashour et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Pandemic of Publications: Are We Sacrificing Quality for Quantity?

(2020) Russell Seth Martins et al.   MAYO CLINIC PROCEEDINGS

Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

Drug repurposing approach to fight COVID-19

(2020) Thakur Uttam Singh et al.   Pharmacological Reports

Hydroxychloroquine in hospitalized COVID‐19 patients: Real world experience assessing mortality

(2020) Frank H. Annie et al.   PHARMACOTHERAPY

Comparing the impact of Hydroxychloroquine based regimens and standard treatment on COVID-19 patient outcomes: A retrospective cohort study

(2020) Saja H. Almazrou et al.   SAUDI PHARMACEUTICAL JOURNAL

Characteristics and outcomes of acute respiratory distress syndrome related to COVID-19 in Belgian and French intensive care units according to antiviral strategies: the COVADIS multicentre observational study

(2020) David Grimaldi et al.   Annals of Intensive Care

Treating Covid-19 With Hydroxychloroquine (TEACH): A Multicenter, Double-Blind, Randomized Controlled Trial in Hospitalized Patients

(2020) Robert J Ulrich et al.   Open Forum Infectious Diseases

Hydroxychloroquine/azithromycin treatment, QT interval and ventricular arrhythmias in hospitalised patients with COVID‐19

(2020) İbrahim Halil Özdemir et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19

(2020) Wesley H. Self et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Hydroxychloroquine is associated with slower viral clearance in clinical COVID-19 patients with mild to moderate disease

(2020) Jihad Mallat et al.   MEDICINE

A multicenter, randomized, open-label, controlled trial to evaluate the efficacy and tolerability of hydroxychloroquine and a retrospective study in adult patients with mild to moderate coronavirus disease 2019 (COVID-19)

(2020) Cheng-Pin Chen et al.   PLoS One

A systematic review and meta-analysis on chloroquine and hydroxychloroquine as monotherapy or combined with azithromycin in COVID-19 treatment

(2020) Ramy Mohamed Ghazy et al.   Scientific Reports

Structural basis for human coronavirus attachment to sialic acid receptors

(2019) M. Alejandra Tortorici et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RoB 2: a revised tool for assessing risk of bias in randomised trials

(2019) Jonathan A C Sterne et al.   BMJ-British Medical Journal

Methods to systematically review and meta-analyse observational studies: a systematic scoping review of recommendations

(2018) Monika Mueller et al.   BMC Medical Research Methodology

Host Lipid Rafts Play a Major Role in Binding and Endocytosis of Influenza A Virus

(2018) Dileep Verma et al.   Viruses-Basel

Clinical Practice Guidelines

(2017) M. Hassan Murad   MAYO CLINIC PROCEEDINGS

Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice

(2017) Chunfeng Li et al.   EBioMedicine

Optimally estimating the sample mean from the sample size, median, mid-range, and/or mid-quartile range

(2016) Dehui Luo et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Chloroquine, an Endocytosis Blocking Agent, Inhibits Zika Virus Infection in Different Cell Models

(2016) Rodrigo Delvecchio et al.   Viruses-Basel

ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions

(2016) Jonathan AC Sterne et al.   BMJ-British Medical Journal

ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions

(2016) Jonathan AC Sterne et al.   BMJ-British Medical Journal

Chloroquine inhibited Ebola virus replication in vitro but failed to protect against infection and disease in the in vivo guinea pig model

(2015) Stuart D. Dowall et al.   JOURNAL OF GENERAL VIROLOGY

Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range

(2015) Xiang Wan et al.   BMC Medical Research Methodology

Macrolide Antibiotics and the Risk of Cardiac Arrhythmias

(2014) Richard K. Albert et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture

(2014) Adriaan H. de Wilde et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Systematic Screen of FDA-Approved Drugs for Inhibitors of Biological Threat Agents

(2013) Peter B. Madrid et al.   PLoS One

Chloroquine Inhibits Dengue Virus Type 2 Replication in Vero Cells but Not in C6/36 Cells

(2013) Kleber Juvenal Silva Farias et al.   TheScientificWorldJOURNAL

Effects of Hydroxychloroquine on Immune Activation and Disease Progression Among HIV-Infected Patients Not Receiving Antiretroviral Therapy

(2012) Nicholas I. Paton et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Assessment of in vitro prophylactic and therapeutic efficacy of chloroquine against chikungunya virus in vero cells

(2010) Mohsin Khan et al.   JOURNAL OF MEDICAL VIROLOGY

A Randomized Controlled Trial of Chloroquine for the Treatment of Dengue in Vietnamese Adults

(2010) Vianney Tricou et al.   PLoS Neglected Tropical Diseases

Lipid rafts are involved in SARS-CoV entry into Vero E6 cells

(2008) Yanning Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

On Chikungunya Acute Infection and Chloroquine Treatment

(2008) Xavier De Lamballerie et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

GRADE: an emerging consensus on rating quality of evidence and strength of recommendations

(2008) Gordon H Guyatt et al.   BMJ-British Medical Journal