Reduced expression of TAZ inhibits primary cilium formation in renal glomeruli

A spatial model of YAP/TAZ signaling reveals how stiffness, dimensionality, and shape contribute to emergent outcomes

(2021) Kiersten Elizabeth Scott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

YAP and TAZ Negatively Regulate Prox1 During Developmental and Pathologic Lymphangiogenesis

(2019) Hyunsoo Cho et al.   CIRCULATION RESEARCH

The YAP/TAZ transcriptional co-activators have opposing effects at different stages of osteoblast differentiation

(2018) Jinhu Xiong et al.   BONE

Cell type‐specific regulation of ciliary transition zone assembly in vertebrates

(2018) Antonia Wiegering et al.   EMBO JOURNAL

Interaction of WDR60 intermediate chain with TCTEX1D2 light chain of the dynein-2 complex is crucial for ciliary protein trafficking

(2018) Yuki Hamada et al.   MOLECULAR BIOLOGY OF THE CELL

Many Genes—One Disease? Genetics of Nephronophthisis (NPHP) and NPHP-Associated Disorders

(2018) Shalabh Srivastava et al.   Frontiers in Pediatrics

Obesity in Yap transgenic mice is associated with TAZ downregulation

(2018) Keiichiro Kamura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Intraflagellar Transport Complex A Genes Differentially Regulate Cilium Formation and Transition Zone Gating

(2018) Noémie Scheidel et al.   CURRENT BIOLOGY

Jasplakinolide induces primary cilium formation through cell rounding and YAP inactivation

(2017) Tomoaki Nagai et al.   PLoS One

Common and Distinctive Functions of the Hippo Effectors Taz and Yap in Skeletal Muscle Stem Cell Function

(2017) Congshan Sun et al.   STEM CELLS

YAP/TAZ at the Roots of Cancer

(2016) Francesca Zanconato et al.   CANCER CELL

Kidney-specific knockout ofSav1in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway

(2016) Tomoki Kai et al.   JOURNAL OF PATHOLOGY

Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation

(2016) Valentina Grampa et al.   PLoS Genetics

TAZ Protein Accumulation Is Negatively Regulated by YAP Abundance in Mammalian Cells

(2015) Megan L. Finch-Edmondson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes

(2015) Gabrielle Wheway et al.   NATURE CELL BIOLOGY

IFT–Cargo Interactions and Protein Transport in Cilia

(2015) Karl F. Lechtreck   TRENDS IN BIOCHEMICAL SCIENCES

Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking

(2015) Jongshin Kim et al.   Nature Communications

The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis

(2014) Miju Kim et al.   Nature Communications

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel mutation causing nephronophthisis in the Lewis polycystic kidney rat localises to a conserved RCC1 domain in Nek8

(2012) John K McCooke et al.   BMC GENOMICS

The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ

(2012) Sandra Habbig et al.   HUMAN MOLECULAR GENETICS

Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis

(2012) Rivka A. Rachel et al.   JOURNAL OF CLINICAL INVESTIGATION

NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway

(2011) Sandra Habbig et al.   JOURNAL OF CELL BIOLOGY

YAP, TAZ, and Yorkie: a conserved family of signal-responsive transcriptional coregulators in animal development and human diseaseThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

(2009) Kainan Wang et al.   Biochemistry and Cell Biology

Glis3 Is Associated with Primary Cilia and Wwtr1/TAZ and Implicated in Polycystic Kidney Disease

(2009) H. S. Kang et al.   MOLECULAR AND CELLULAR BIOLOGY

Nek8 Regulates the Expression and Localization of Polycystin-1 and Polycystin-2

(2008) E. Sohara et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY