Senescence and impaired DNA damage responses in alpha-synucleinopathy models

Transcriptome signature of cellular senescence

(2019) Gabriel Casella et al.   NUCLEIC ACIDS RESEARCH

Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders

(2019) Allison J. Schaser et al.   Scientific Reports

Mitochondrial Homeostasis and Cellular Senescence

(2019) Panagiotis V.S. Vasileiou et al.   Cells

RankerGUI: A Computational Framework to Compare Differential Gene Expression Profiles Using Rank Based Statistics

(2019) Amarinder Singh Thind et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ageing, Cellular Senescence and Neurodegenerative Disease

(2018) Marios Kritsilis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

20 Years of Mre11 Biology: No End in Sight

(2018) Tanya T. Paull   MOLECULAR CELL

Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson’s disease

(2018) Chiara Milanese et al.   Cell Death & Disease

Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage

(2017) Isabel Paiva et al.   HUMAN MOLECULAR GENETICS

DNA damage preceding dopamine neuron degeneration in A53T human α-synuclein transgenic mice

(2016) Degui Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ATM kinase: Much more than a DNA damage responsive protein

(2016) Ayushi Guleria et al.   DNA REPAIR

Altered Proteins in the Aging Brain

(2016) Adila Elobeid et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Structural disorder of monomeric α-synuclein persists in mammalian cells

(2016) Francois-Xavier Theillet et al.   NATURE

Ageing, neurodegeneration and brain rejuvenation

(2016) Tony Wyss-Coray   NATURE

Chronic stress and moderate physical exercise prompt widespread common activation and limited differential activation in specific brain regions

(2016) Tae-Kyung Kim et al.   NEUROCHEMISTRY INTERNATIONAL

Systemic DNA damage responses in aging and diseases

(2016) Flavia Ribezzo et al.   SEMINARS IN CANCER BIOLOGY

ATF6α regulates morphological changes associated with senescence in human fibroblasts

(2016) Clémentine Druelle et al.   Oncotarget

G9a-Mediated Regulation of OXT and AVP Expression in the Basolateral Amygdala Mediates Stress-Induced Lasting Behavioral Depression and Its Reversal by Exercise

(2015) Tae-Kyung Kim et al.   MOLECULAR NEUROBIOLOGY

The impact of base excision DNA repair in age-related neurodegenerative diseases

(2015) Giovana S. Leandro et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

DNA Damage, DNA Repair, Aging, and Neurodegeneration

(2015) Scott Maynard et al.   Cold Spring Harbor Perspectives in Medicine

Phospholipase D1 regulates autophagic flux and clearance of α-synuclein aggregates

(2014) E-J Bae et al.   CELL DEATH AND DIFFERENTIATION

DNA Damage and Its Links to Neurodegeneration

(2014) Ram Madabhushi et al.   NEURON

53BP1: pro choice in DNA repair

(2013) Michal Zimmermann et al.   TRENDS IN CELL BIOLOGY

A senescent cell bystander effect: senescence-induced senescence

(2012) Glyn Nelson et al.   AGING CELL

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

(2012) Diana Jurk et al.   AGING CELL

Diseases Associated with Defective Responses to DNA Damage

(2012) M. O'Driscoll   Cold Spring Harbor Perspectives in Biology

The MRE11 complex: starting from the ends

(2011) Travis H. Stracker et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DNA repair deficiency in neurodegeneration

(2011) Dennis Kjølhede Jeppesen et al.   PROGRESS IN NEUROBIOLOGY

Plasma membrane microdomains in aging and disease

(2010) Yoshiko Ohno-Iwashita et al.   Geriatrics & Gerontology International

Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies

(2010) He-Jin Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of  -synuclein

(2009) P. Desplats et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA