Concept and application of circulating proteasomes

Structural Insights into Substrate Recognition and Processing by the 20S Proteasome

(2021) Indrajit Sahu et al.   Biomolecules

Moving fluid biomarkers for Alzheimer’s disease from research tools to routine clinical diagnostics

(2021) Henrik Zetterberg et al.   Molecular Neurodegeneration

Regulation of the 20S Proteasome by a Novel Family of Inhibitory Proteins

(2020) Maya A. Olshina et al.   ANTIOXIDANTS & REDOX SIGNALING

Circulating 20S proteasome for assessing protein energy wasting syndrome in hemodialysis patients

(2020) Julien Aniort et al.   PLoS One

Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes

(2020) Won Hoon Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution

(2020) T. Ukmar-Godec et al.   Science Advances

Proteasome Activity in the Plasma as a Novel Biomarker in Mild Cognitive Impairment with Chronic Tinnitus

(2020) Yejin Yun et al.   JOURNAL OF ALZHEIMERS DISEASE

Beyond cells: The extracellular circulating 20S proteasomes

(2020) Vandita Dwivedi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Negative-feedback coordination between proteasomal activity and autophagic flux

(2019) Jung Hoon Lee et al.   Autophagy

Proteasome 19S RP and translation preinitiation complexes are secreted within exosomes upon serum starvation

(2019) Nicole Bec et al.   TRAFFIC

The Contribution of the 20S Proteasome to Proteostasis

(2019) Fanindra Kumar Deshmukh et al.   Biomolecules

Immunoproteasome in the Plasma of Pediatric Patients With Moderate and Major Burns, and Its Correlation With Proteasome and UCHL1 Measured by SPR Imaging Biosensors

(2018) Ewa Matuszczak et al.   Journal of Burn Care & Research

Proteasome Activity and C-Reactive Protein Concentration in the Course of Inflammatory Reaction in Relation to the Type of Abdominal Operation and the Surgical Technique Used

(2018) Marzena Tylicka et al.   MEDIATORS OF INFLAMMATION

Concentration of Proteasome in the Blood Plasma of Children with Acute Appendicitis, Before and After Surgery, and Its Correlation with CRP

(2017) Ewa Matuszczak et al.   WORLD JOURNAL OF SURGERY

Tuning the proteasome to brighten the end of the journey

(2016) Thibault Mayor et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Isolation and Characterization of RNA Aptamers against a Proteasome-Associated Deubiquitylating Enzyme UCH37

(2016) Jung Hoon Lee et al.   CHEMBIOCHEM

Enzymatic activities of circulating plasma proteasomes in newly diagnosed multiple myeloma patients treated with carfilzomib, lenalidomide and dexamethasone

(2016) Elisabet E. Manasanch et al.   LEUKEMIA & LYMPHOMA

Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation

(2016) Won Hoon Choi et al.   Nature Communications

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

The Parkinson’s-associated protein DJ-1 regulates the 20S proteasome

(2015) Oren Moscovitz et al.   Nature Communications

Facilitated Tau Degradation by USP14 Aptamers via Enhanced Proteasome Activity

(2015) Jung Hoon Lee et al.   Scientific Reports

Circulating 20S Proteasome Is Independently Associated with Abdominal Muscle Mass in Hemodialysis Patients

(2015) Hirotaka Fukasawa et al.   PLoS One

Circulating proteasome activity following mild head injury in children

(2014) Marzena Tylicka et al.   CHILDS NERVOUS SYSTEM

The Mechanistic Links Between Proteasome Activity, Aging and Agerelated Diseases

(2014) Isabel Saez et al.   CURRENT GENOMICS

Label-Free Quantitative Proteomics Reveals the Dynamics of Proteasome Complexes Composition and Stoichiometry in a Wide Range of Human Cell Lines

(2014) Bertrand Fabre et al.   JOURNAL OF PROTEOME RESEARCH

Assessment of proteasome concentration and chymotrypsin-like activity in plasma of patients with newly diagnosed multiple myeloma

(2014) Agnieszka Oldziej et al.   LEUKEMIA RESEARCH

Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome

(2014) Chan-Gi Pack et al.   Nature Communications

T lymphocytes export proteasomes by way of microparticles: a possible mechanism for generation of extracellular proteasomes

(2013) Isabel Bochmann et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Serum 20S proteasome is elevated in patients with renal cell carcinoma and associated with poor prognosis

(2012) M de Martino et al.   BRITISH JOURNAL OF CANCER

Clinical use of p-proteasome in discriminating metastatic melanoma patients: Comparative study with LDH, MIA and S100B protein

(2012) Laurent Henry et al.   INTERNATIONAL JOURNAL OF CANCER

Orderly order in protein intrinsic disorder distribution: disorder in 3500 proteomes from viruses and the three domains of life

(2012) Bin Xue et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Subcellular Distribution and Dynamics of Active Proteasome Complexes Unraveled by a Workflow Combiningin VivoComplex Cross-Linking and Quantitative Proteomics

(2012) Bertrand Fabre et al.   MOLECULAR & CELLULAR PROTEOMICS

Complete subunit architecture of the proteasome regulatory particle

(2012) Gabriel C. Lander et al.   NATURE

Near-atomic resolution structural model of the yeast 26S proteasome

(2012) F. Beck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-β Peptide Is a Substrate of the Human 20S Proteasome

(2010) Xiaobei Zhao et al.   ACS Chemical Neuroscience

The prognostic impact of circulating proteasome concentrations in patients with epithelial ovarian cancer

(2010) Martin Heubner et al.   GYNECOLOGIC ONCOLOGY

Circulating Proteasomes After Burn Injury

(2010) Matthias Majetschak et al.   Journal of Burn Care & Research

Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome

(2009) Daniel Finley   Annual Review of Biochemistry

Proteasome Enzymatic Activities in Plasma as Risk Stratification of Patients with Acute Myeloid Leukemia and Advanced-Stage Myelodysplastic Syndrome

(2009) W. Ma et al.   CLINICAL CANCER RESEARCH

Therapeutic Targets in Extracellular Protein Deposition Diseases

(2009) A. Wyatt et al.   CURRENT MEDICINAL CHEMISTRY

Plasma proteasome level is a reliable early marker of malignant transformation of liver cirrhosis

(2009) L Henry et al.   GUT

Proteasomes Can Degrade a Significant Proportion of Cellular Proteins Independent of Ubiquitination

(2009) James M. Baugh et al.   JOURNAL OF MOLECULAR BIOLOGY

The proteasome: Overview of structure and functions

(2009) Keiji TANAKA   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Enzymatic activity of circulating proteasomes correlates with clinical behavior in patients with chronic lymphocytic leukemia

(2008) Wanlong Ma et al.   CANCER

Circulating 20S Proteasome Levels in Patients with Mixed Connective Tissue Disease and Systemic Lupus Erythematosus

(2008) M. Majetschak et al.   Clinical and Vaccine Immunology