Pre-existing Castration-resistant Prostate Cancer–like Cells in Primary Prostate Cancer Promote Resistance to Hormonal Therapy

Title
Pre-existing Castration-resistant Prostate Cancer–like Cells in Primary Prostate Cancer Promote Resistance to Hormonal Therapy
Authors
Keywords
Castration-resistant prostate cancer, Primary prostate cancer, Single-cell transcriptomes, Intratumor heterogeneity, Castration-resistant prostate cancer–like cells, Evolutionary trajectory, Critical transcription regulator, Neuroendocrine differentiation, Large population validation
Journal
EUROPEAN UROLOGY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2022-01-18
DOI
10.1016/j.eururo.2021.12.039

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