Selection and adaptation during metastatic cancer progression

Tumor Cell Dissemination: Emerging Biological Insights from Animal Models and Cancer Patients

(2013) Yibin Kang et al.   CANCER CELL

Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing

(2013) E. Heitzer et al.   CANCER RESEARCH

Gene Copy-Number Alterations: A Cost-Benefit Analysis

(2013) Yun-Chi Tang et al.   CELL

Mechanisms of cell competition: Themes and variations

(2013) Romain Levayer et al.   JOURNAL OF CELL BIOLOGY

The perivascular niche regulates breast tumour dormancy

(2013) Cyrus M. Ghajar et al.   NATURE CELL BIOLOGY

Metastasis Awakening: The challenges of targeting minimal residual cancer

(2013) Bernhard Polzer et al.   NATURE MEDICINE

Isolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer

(2012) Mark Jesus M Magbanua et al.   BMC CANCER

Genetic and epigenetic alterations in primary colorectal cancers and related lymph node and liver metastases

(2012) Elena Miranda et al.   CANCER

Genomic Profiling of Isolated Circulating Tumor Cells from Metastatic Breast Cancer Patients

(2012) M. J. M. Magbanua et al.   CANCER RESEARCH

The serrated pathway to colorectal carcinoma: current concepts and challenges

(2012) Mark Bettington et al.   HISTOPATHOLOGY

Cerebral Hemorrhage, Warfarin, and Intravenous tPA

(2012) Mark J. Alberts   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Clonal evolution of high-grade serous ovarian carcinoma from primary to recurrent disease

(2012) Mauro Castellarin et al.   JOURNAL OF PATHOLOGY

Perspective: The right trials

(2012) Patricia S. Steeg   NATURE

Clonal evolution in cancer

(2012) Mel Greaves et al.   NATURE

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Survival in BRAF V600–Mutant Advanced Melanoma Treated with Vemurafenib

(2012) Jeffrey A. Sosman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hematogenous and lymphatic tumor cell dissemination may be detected in patients diagnosed with ductal carcinoma in situ of the breast

(2011) Malgorzata Banys et al.   BREAST CANCER RESEARCH AND TREATMENT

Positive lymph nodes do not metastasize

(2011) Jutta Engel et al.   CANCER AND METASTASIS REVIEWS

Tyrosine Isomers Mediate the Classical Phenomenon of Concomitant Tumor Resistance

(2011) R. A. Ruggiero et al.   CANCER RESEARCH

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

(2011) Philip J. Stephens et al.   CELL

Identification of Aneuploidy-Selective Antiproliferation Compounds

(2011) Yun-Chi Tang et al.   CELL

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Primary Colorectal Cancers and Their Subsequent Hepatic Metastases Are Genetically Different: Implications for Selection of Patients for Targeted Treatment

(2011) J. S. Vermaat et al.   CLINICAL CANCER RESEARCH

Histologic characteristics of non–microsatellite-instable colon adenomas correlate with distinct molecular patterns

(2011) Agnès Neuville et al.   HUMAN PATHOLOGY

Disseminated tumor cells in the bone marrow of patients with ductal carcinoma in situ

(2011) Nicole Sänger et al.   INTERNATIONAL JOURNAL OF CANCER

Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow

(2011) Yusuke Shiozawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer

(2011) Wigard P Kloosterman et al.   GENOME BIOLOGY

Distant metastases do not metastasize

(2010) Dieter Hölzel et al.   CANCER AND METASTASIS REVIEWS

Framework models of tumor dormancy from patient-derived observations

(2010) Christoph A Klein   CURRENT OPINION IN GENETICS & DEVELOPMENT

Epithelial Cell Adhesion Molecule Regulation Is Associated with the Maintenance of the Undifferentiated Phenotype of Human Embryonic Stem Cells

(2010) Tung-Ying Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype

(2010) So Yeon Park et al.   JOURNAL OF CLINICAL INVESTIGATION

Randomized, Phase III Trial of Panitumumab With Infusional Fluorouracil, Leucovorin, and Oxaliplatin (FOLFOX4) Versus FOLFOX4 Alone As First-Line Treatment in Patients With Previously Untreated Metastatic Colorectal Cancer: The PRIME Study

(2010) Jean-Yves Douillard et al.   JOURNAL OF CLINICAL ONCOLOGY

Metastatic Behavior of Breast Cancer Subtypes

(2010) Hagen Kennecke et al.   JOURNAL OF CLINICAL ONCOLOGY

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

(2010) Peter J. Campbell et al.   NATURE

Genome remodelling in a basal-like breast cancer metastasis and xenograft

(2010) Li Ding et al.   NATURE

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

(2010) Shinichi Yachida et al.   NATURE

Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors

(2010) C. Hafner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lessons from an Aggressive Cancer: Evolutionary Dynamics in Esophageal Carcinoma

(2009) Christoph A. Klein et al.   CANCER RESEARCH

Genetic disparity between primary tumours, disseminated tumour cells, and manifest metastasis

(2009) Nikolas H. Stoecklein et al.   INTERNATIONAL JOURNAL OF CANCER

Perioperative Activation of Disseminated Tumor Cells in Bone Marrow of Patients With Prostate Cancer

(2009) Dorothea Weckermann et al.   JOURNAL OF CLINICAL ONCOLOGY

Serrated and non-serrated polyps of the colorectum: their prevalence in an unselected case series and correlation of BRAF mutation analysis with the diagnosis of sessile serrated adenoma

(2009) N J Carr et al.   JOURNAL OF CLINICAL PATHOLOGY

Lymphadenectomy in endometrial cancer – Authors' reply

(2009) Henry Kitchener et al.   LANCET

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

(2009) Sohrab P. Shah et al.   NATURE

Genes that mediate breast cancer metastasis to the brain

(2009) Paula D. Bos et al.   NATURE

Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma

(2009) Tony S. Mok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Competitive Interactions Between Cells: Death, Growth, and Geography

(2009) L. A. Johnston   SCIENCE

Characterization of Epithelial Cell Adhesion Molecule as a Surface Marker on Undifferentiated Human Embryonic Stem Cells

(2009) Valerie Y. Ng et al.   STEM CELLS

Saltational evolution: hopeful monsters are here to stay

(2009) Günter Theißen   THEORY IN BIOSCIENCES

Systemic Spread Is an Early Step in Breast Cancer

(2008) Yves Hüsemann et al.   CANCER CELL

Direct Genetic Analysis of Single Disseminated Cancer Cells for Prediction of Outcome and Therapy Selection in Esophageal Cancer

(2008) Nikolas H. Stoecklein et al.   CANCER CELL

Systemic Endocrine Instigation of Indolent Tumor Growth Requires Osteopontin

(2008) Sandra S. McAllister et al.   CELL

Markers that define stemness in ESC are unable to identify the totipotent cells in human preimplantation embryos

(2008) G. Cauffman et al.   HUMAN REPRODUCTION

Review: Biological relevance of disseminated tumor cells in cancer patients

(2008) Sabine Riethdorf et al.   INTERNATIONAL JOURNAL OF CANCER

The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

(2008) Sachie Hiratsuka et al.   NATURE CELL BIOLOGY

Cell-cell contact interactions conditionally determine suppression and selection of the neoplastic phenotype

(2008) H. Rubin   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA