RNF168 suppresses the cancer stem cell‐like traits of nonsmall cell lung cancer cells by mediating RhoC ubiquitination

RNF168 is highly expressed in esophageal squamous cell carcinoma and contributes to the malignant behaviors in association with the Wnt/β-catenin signaling pathway

(2021) Yunjiu Gou et al.   Aging-US

RNF168 promotes RHOC degradation by ubiquitination to restrain gastric cancer progression via decreasing HDAC1 expression

(2021) Ying Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RhoGTPase Signalling in Cancer Progression and Dissemination

(2021) Eva Crosas-Molist et al.   PHYSIOLOGICAL REVIEWS

TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer

(2021) Jiahui Xu et al.   Nature Communications

RNF168-mediated ubiquitin signaling inhibits the viability of BRCA1 null cancers

(2020) John J. Krais et al.   CANCER RESEARCH

Long non-coding RNA NEAT1 confers oncogenic role in triple-negative breast cancer through modulating chemoresistance and cancer stemness

(2019) Vivian Yvonne Shin et al.   Cell Death & Disease

Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response

(2019) Yinfang Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cancer statistics: a comparison between World Health Organization (WHO) and Global Burden of Disease (GBD)

(2019) Camilla Mattiuzzi et al.   EUROPEAN JOURNAL OF PUBLIC HEALTH

RNF168 facilitates oestrogen receptor ɑ transcription and drives breast cancer proliferation

(2018) Zhenhua Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

RNF168 facilitates proliferation and invasion of esophageal carcinoma, possibly via stabilizing STAT1

(2018) Na Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lung cancer stem cells: origin, features, maintenance mechanisms and therapeutic targeting

(2018) Win Sen Heng et al.   BIOCHEMICAL PHARMACOLOGY

XIAP overexpression promotes bladder cancer invasion in vitro and lung metastasis in vivo via enhancing nucleolin-mediated Rho-GDIβ mRNA stability

(2017) Yonghui Yu et al.   INTERNATIONAL JOURNAL OF CANCER

RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer

(2017) Chao Yan et al.   PHARMACOLOGICAL REVIEWS

Clinical and Biological Manifestation of RNF168 Deficiency in Two Polish Siblings

(2017) Barbara Pietrucha et al.   Frontiers in Immunology

Redox Regulation of Stem-like Cells Though the CD44v-xCT Axis in Colorectal Cancer: Mechanisms and Therapeutic Implications

(2016) Huai-Qiang Ju et al.   Theranostics

RhoC Regulates Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma by Overexpressing IL-6 and Phosphorylation of STAT3

(2014) Mozaffarul Islam et al.   PLoS One

Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance

(2013) Wen Yue et al.   Autophagy

RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks

(2013) M. Bohgaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling

(2012) Francesca Mattiroli et al.   CELL

Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy

(2012) Libero Santarpia et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX

(2009) Sabrina Pinato et al.   BMC MOLECULAR BIOLOGY