Nickel oxide nanoparticles induce apoptosis and ferroptosis in airway epithelial cells via ATF3

LncRNA MEG3 mediates nickel oxide nanoparticles‐induced pulmonary fibrosis via suppressing TGF ‐β1 expression and epithelial‐mesenchymal transition process

(2021) Haibing Zhan et al.   ENVIRONMENTAL TOXICOLOGY

Panaxydol attenuates ferroptosis against LPS-induced acute lung injury in mice by Keap1-Nrf2/HO-1 pathway

(2021) Jiucui Li et al.   Journal of Translational Medicine

SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO

(2021) Jing Wu et al.   Cell Reports

Ferroptosis and its potential as a therapeutic target

(2021) Hanshu Yuan et al.   BIOCHEMICAL PHARMACOLOGY

ATF3 Promotes Arsenic-Induced Apoptosis and Oppositely Regulates DR5 and Bcl-xL Expression in Human Bronchial Epithelial Cells

(2021) Qiwen Shi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ferrostatin-1 alleviates lipopolysaccharide-induced acute lung injury via inhibiting ferroptosis

(2020) Pengfei Liu et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Inhibitor of apoptosis-stimulating protein of p53 inhibits ferroptosis and alleviates intestinal ischemia/reperfusion-induced acute lung injury

(2020) Yingchuan Li et al.   CELL DEATH AND DIFFERENTIATION

“Iron free” zinc oxide nanoparticles with ion-leaking properties disrupt intracellular ROS and iron homeostasis to induce ferroptosis

(2020) Changping Zhang et al.   Cell Death & Disease

Transcriptome Profiling and Toxicity Following Long-Term, Low Dose Exposure of Human Lung Cells to Ni and NiO Nanoparticles—Comparison with NiCl2

(2020) Anda R. Gliga et al.   Nanomaterials

NOXA upregulation by the prohibitin‐binding compound fluorizoline is transcriptionally regulated by integrated stress response‐induced ATF3 and ATF4

(2020) Sonia Núñez‐Vázquez et al.   FEBS Journal

Pseudomonas Aeruginosa Induced Cell Death in Acute Lung Injury and Acute Respiratory Distress Syndrome

(2020) Rushikesh Deshpande et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Zinc Oxide Nanoparticles Induce Ferroptotic Neuronal Cell Death in vitro and in vivo

(2020) Xia Qin et al.   International Journal of Nanomedicine

Master Regulator Activating Transcription Factor 3 (ATF3) in Metabolic Homeostasis and Cancer

(2020) Hui-Chen Ku et al.   Frontiers in Endocrinology

Toxic Effects of Low-Level Long-Term Inhalation Exposures of Rats to Nickel Oxide Nanoparticles

(2019) Sutunkova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ATF3 promotes erastin-induced ferroptosis by suppressing system Xc–

(2019) Liyuan Wang et al.   CELL DEATH AND DIFFERENTIATION

Nickel oxide nanoparticles exert selective toxicity on skin mitochondria and lysosomes isolated from the mouse model of melanoma

(2019) Shabnam Rahimi et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis

(2019) Masahiro Yoshida et al.   Nature Communications

Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4‐ATF3‐CHOP axis

(2019) Qin Tang et al.   CELL PROLIFERATION

Arsenic induces pancreatic dysfunction and ferroptosis via mitochondrial ROS-autophagy-lysosomal pathway

(2019) Sen Wei et al.   JOURNAL OF HAZARDOUS MATERIALS

High molecular weight hyaluronan attenuates fine particulate matter-induced acute lung injury through inhibition of ROS-ASK1-p38/JNK-mediated epithelial apoptosis

(2018) Chenming Xu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Ferroptosis-Induced Endoplasmic Reticulum Stress: Cross-talk between Ferroptosis and Apoptosis

(2018) Young-Sun Lee et al.   MOLECULAR CANCER RESEARCH

Calcium-dependent cyto- and genotoxicity of nickel metal and nickel oxide nanoparticles in human lung cells

(2018) Sebastiano Di Bucchianico et al.   Particle and Fibre Toxicology

ATF3 is positively involved in particulate matter-induced airway inflammation in vitro and in vivo

(2018) Fugui Yan et al.   TOXICOLOGY LETTERS

The ferroptosis inducer erastin irreversibly inhibits system xc− and synergizes with cisplatin to increase cisplatin’s cytotoxicity in cancer cells

(2018) Mami Sato et al.   Scientific Reports

Ferroptosis: A Novel Anti-tumor Action for Cisplatin

(2018) Jipeng Guo et al.   Cancer Research and Treatment

Role of activating transcription factor 3 and its interacting proteins under physiological and pathological conditions

(2018) M. Rohini et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Cell Death in the Lung: The Apoptosis–Necroptosis Axis

(2018) Maor Sauler et al.   Annual Review of Physiology

RSL3 Drives Ferroptosis Through GPX4 Inactivation and ROS Production in Colorectal Cancer

(2018) Xinbing Sui et al.   Frontiers in Pharmacology

Nickel oxide nanoparticles induce hepatocyte apoptosis via activating endoplasmic reticulum stress pathways in rats

(2017) Xuhong Chang et al.   ENVIRONMENTAL TOXICOLOGY

Activating transcription factor 3 (ATF3) protects against lipopolysaccharide-induced acute lung injury via inhibiting the expression of TL1A

(2017) Lanlan Qian et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Investigation into the pulmonary inflammopathology of exposure to nickel oxide nanoparticles in mice

(2017) Kuan-Jen Bai et al.   Nanomedicine-Nanotechnology Biology and Medicine

The common stress responsive transcription factor ATF3 binds genomic sites enriched with p300 and H3K27ac for transcriptional regulation

(2016) Jonathan Zhao et al.   BMC GENOMICS

Role of NF-κ B activation and Th1/Th2 imbalance in pulmonary toxicity induced by nano NiO

(2016) Xuhong Chang et al.   ENVIRONMENTAL TOXICOLOGY

Nickel Release, ROS Generation and Toxicity of Ni and NiO Micro- and Nanoparticles

(2016) Siiri Latvala et al.   PLoS One

NiO nanoparticles induce apoptosis through repressing SIRT1 in human bronchial epithelial cells

(2015) Wei-Xia Duan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60

(2015) Hongmei Cui et al.   Nature Communications

Nickel oxide nanoparticles induce inflammation and genotoxic effect in lung epithelial cells

(2014) Laura Capasso et al.   TOXICOLOGY LETTERS

Comparison of acute oxidative stress on rat lung induced by nano and fine-scale, soluble and insoluble metal oxide particles: NiO and TiO2

(2012) Masanori Horie et al.   INHALATION TOXICOLOGY

Elucidating the mechanisms of nickel compound uptake: A review of particulate and nano-nickel endocytosis and toxicity

(2011) Alexandra Muñoz et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Activating Transcription Factor 3 Confers Protection against Ventilator-induced Lung Injury

(2010) Ali Akram et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Expression of stress-response ATF3 is mediated by Nrf2 in astrocytes

(2009) Kyu-Han Kim et al.   NUCLEIC ACIDS RESEARCH

Activating Transcription Factor 3 Is a Novel Repressor of the Nuclear Factor Erythroid-Derived 2 Related Factor 2 (Nrf2) Regulated Stress Pathway

(2008) S. L. Brown et al.   CANCER RESEARCH