Cadmium exposure activates the PI3K/AKT signaling pathway through miRNA-21, induces an increase in M1 polarization of macrophages, and leads to fibrosis of pig liver tissue

Cadmium induces apoptosis of pig lymph nodes by regulating the PI3K/AKT/HIF-1α pathway

(2021) Lu Yiming et al.   TOXICOLOGY

New insights into crosstalk between pyroptosis and autophagy co-induced by molybdenum and cadmium in duck renal tubular epithelial cells

(2021) Caiying Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

The impact of Sambucus nigra L. extract on inflammation, oxidative stress and tissue remodeling in a rat model of lipopolysaccharide-induced subacute rhinosinusitis

(2021) C. N. Tiboc Schnell et al.   INFLAMMOPHARMACOLOGY

Selenium Deficiency Aggravates Heat Stress Pneumonia in Chickens by Disrupting the M1/M2 Balance

(2021) Yilin Yin et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

New insights into crosstalk between apoptosis and necroptosis co-induced by chlorothalonil and imidacloprid in Ctenopharyngodon idellus kidney cells

(2021) Xiaojing Li et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Subacute cadmium exposure promotes M1 macrophage polarization through oxidative stress-evoked inflammatory response and induces porcine adrenal fibrosis

(2021) Yujie Yao et al.   TOXICOLOGY

Pig lung fibrosis is active in the subacute CdCl2 exposure model and exerts cumulative toxicity through the M1/M2 imbalance

(2021) Shi Xu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Systemic inflammation mediates the association of heavy metal exposures with liver injury: A study in general Chinese urban adults

(2021) Xing Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Whole transcriptome-based miRNA-mRNA network analysis revealed the mechanism of inflammation-immunosuppressive damage caused by cadmium in common carp spleens

(2020) Jianqing Chen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The systematic exploration of cadmium-accumulation characteristics of maize kernel in acidic soil with different pollution levels in China

(2020) Lu Feng et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Mortality Trends of Idiopathic Pulmonary Fibrosis in the United States From 2004 Through 2017

(2020) Niranjan Jeganathan et al.   CHEST

Cadmium exposure induces pyroptosis of lymphocytes in carp pronephros and spleens by activating NLRP3

(2020) Yiming Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Glyphosate-induced lipid metabolism disorder contributes to hepatotoxicity in juvenile common carp

(2020) Jingbo Liu et al.   ENVIRONMENTAL POLLUTION

Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis

(2019) Priya Handa et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cadmium toxicity: effects on human reproduction and fertility

(2019) Sunil Kumar et al.   REVIEWS ON ENVIRONMENTAL HEALTH

Toxicity of cadmium in musculoskeletal diseases

(2019) D. Reyes-Hinojosa et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

C-reactive protein/serum amyloid P promotes pro-inflammatory function and induces M1-type polarization of monocytes/macrophages in mudskipper, Boleophthalmus pectinirostris

(2019) Shi-Yu Cai et al.   FISH & SHELLFISH IMMUNOLOGY

miR-200c/PAI-2 promotes the progression of triple negative breast cancer via M1/M2 polarization induction of macrophage

(2019) Ziqi Meng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Role of ADAR1 and ADAR2 in the Regulation of miRNA-21 in Idiopathic Pulmonary Fibrosis

(2018) Gabriela Díaz-Piña et al.   LUNG

Cadmium exposure exacerbates hyperlipidemia in cholesterol-overloaded hepatocytes via autophagy dysregulation

(2018) Patricia Rosales-Cruz et al.   TOXICOLOGY

Gynura Rhizoma containing pyrrolizidine alkaloids induces the hepatic sinusoidal obstruction syndrome in mice via upregulating fibrosis-related factors

(2018) Fang Zhang et al.   ACTA PHARMACOLOGICA SINICA

Hepatocellular carcinoma-derived exosomal miRNA-21 contributes to tumor progression by converting hepatocyte stellate cells to cancer-associated fibroblasts

(2018) Yuan Zhou et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Bioaccumulation of cadmium in potato tuber grown on naturally high levels cadmium soils in Jamaica

(2018) Da-Vaugh Sanderson et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Selenium protects against cadmium-induced kidney apoptosis in chickens by activating the PI3K/AKT/Bcl-2 signaling pathway

(2017) Rong-kun Bao et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Cadmium stimulates myofibroblast differentiation and mouse lung fibrosis

(2017) Xin Hu et al.   TOXICOLOGY

Determination of the Lead, Cadmium, and Chromium Concentration in Mineral Feeds and Supplements for Cattle Produced in the Mato Grosso State, Brazil

(2016) Keyla dos Santos Sigarini et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Trillin Reduces Liver Chronic Inflammation and Fibrosis in Carbon Tetrachloride (CCl4) Induced Liver Injury in Mice

(2016) Huabing Tan et al.   IMMUNOLOGICAL INVESTIGATIONS

SMAD7, an antagonist of TGF-beta signaling, is a candidate of prenatal skeletal muscle development and weaning weight in pigs

(2016) Chaoju Hua et al.   MOLECULAR BIOLOGY REPORTS

PI3K/Akt signaling is involved in the pathogenesis of bleomycin-induced pulmonary fibrosis via regulation of epithelial-mesenchymal transition

(2016) Xiao-Ling Zhang et al.   Molecular Medicine Reports

TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype

(2016) Fan Zhang et al.   Oncotarget

MicroRNA-21 Regulates PI3K/Akt/mTOR Signaling by Targeting TGFβI during Skeletal Muscle Development in Pigs

(2015) Lijing Bai et al.   PLoS One

Cadmium Induces Liver Cell Apoptosis through Caspase-3A Activation in Purse Red Common Carp (Cyprinus carpio)

(2013) Dian Gao et al.   PLoS One

Cadmium-induced inflammatory responses in cells relevant for lung toxicity: Expression and release of cytokines in fibroblasts, epithelial cells and macrophages

(2010) Marit Låg et al.   TOXICOLOGY LETTERS

Trace elements in home-produced eggs in Belgium: Levels and spatiotemporal distribution

(2008) Nadia Waegeneers et al.   SCIENCE OF THE TOTAL ENVIRONMENT