A leucine aminopeptidase activatable photosensitizer for cancer cell selective photodynamic therapy action

Multi-dimensional imaging of endogenous leucine aminopeptidase via fast response fluorescent read-out probe

(2021) Haiqing Zhang et al.   DYES AND PIGMENTS

Dual laser activatable brominated hemicyanine as a highly efficient and photostable multimodal phototherapy agent

(2021) Hande Gunduz et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

NIR photosensitizers activated by γ-glutamyl transpeptidase for precise tumor fluorescence imaging and photodynamic therapy

(2021) Yingchao Chen et al.   Science China-Chemistry

A hydrogen peroxide responsive resorufin-based phototheranostic agent for selective treatment of cancer cells

(2021) Toghrul Almammadov et al.   DYES AND PIGMENTS

The detection sensitivity of commonly used singlet oxygen probes in aqueous environments

(2020) Tiago Entradas et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Activatable Photosensitizer for Smart Photodynamic Therapy Triggered by Reactive Oxygen Species in Tumor Cells

(2020) Bin Yuan et al.   ACS Applied Materials & Interfaces

Targeting apoptosis in cancer therapy

(2020) Benedito A. Carneiro et al.   Nature Reviews Clinical Oncology

Personalized Medicine: Recent Progress in Cancer Therapy

(2020) Valentina Gambardella et al.   Cancers

Theranostic applications of smart nanomedicines for tumor-targeted chemotherapy: a review

(2020) Ajkia Zaman Juthi et al.   Environmental Chemistry Letters

Iodinated xanthene-cyanine NIR dyes as potential photosensitizers for antimicrobial photodynamic therapy

(2020) T.M. Ebaston et al.   DYES AND PIGMENTS

Resorufin Enters the Photodynamic Therapy Arena: A Monoamine Oxidase Activatable Agent for Selective Cytotoxicity

(2020) Toghrul Almammadov et al.   ACS Medicinal Chemistry Letters

A ratiometric fluorescent probe based on quinoline for monitoring and imaging of Leucine aminopeptidase in liver tumor cells

(2020) Kui Du et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Photosensitizers for Photodynamic Therapy

(2019) Minhuan Lan et al.   Advanced Healthcare Materials

Iodinated Cyanine Dyes for Fast Near-Infrared-Guided Deep Tissue Synergistic Phototherapy

(2019) Jie Cao et al.   ACS Applied Materials & Interfaces

A single-chromophore-based agent enables rapid sensing of intracellular hypochlorous acid and in-situ photodynamic therapy to cancer cells

(2019) Kaiquan Zhang et al.   ANALYTICA CHIMICA ACTA

Smart cancer nanomedicine

(2019) Roy van der Meel et al.   Nature Nanotechnology

An Activatable Photosensitizer Targeting Human NAD(P)H: Quinone Oxidoreductase 1

(2019) Elyse M. Digby et al.   CHEMISTRY-A EUROPEAN JOURNAL

A turn-on fluorescence probe based on aggregation-induced emission for leucine aminopeptidase in living cells and tumor tissue

(2018) Shuailing Huang et al.   ANALYTICA CHIMICA ACTA

Advanced photosensitizer activation strategies for smarter photodynamic therapy beacons

(2018) Benjamin M Luby et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering of a near-infrared fluorescent probe for real-time simultaneous visualization of intracellular hypoxia and induced mitophagy

(2018) Yongchao Liu et al.   Chemical Science

Simultaneous Discrimination of Cysteine, Homocysteine, Glutathione, and H2S in Living Cells through a Multisignal Combination Strategy

(2018) Hui Zhang et al.   ANALYTICAL CHEMISTRY

Exploiting the Cellular Redox-Control System for Activatable Photodynamic Therapy

(2018) Nima Gharibi et al.   CHEMBIOCHEM

In situ formation of pyronin dyes for fluorescence protease sensing

(2017) Sylvain Debieu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A mitochondrial-targeted prodrug for NIR imaging guided and synergetic NIR photodynamic-chemo cancer therapy

(2017) Hong-Wen Liu et al.   Chemical Science

In vivo imaging of leucine aminopeptidase activity in drug-induced liver injury and liver cancer via a near-infrared fluorescent probe

(2017) Xinyuan He et al.   Chemical Science

ROS-induced cleavage of NHLRC2 by caspase-8 leads to apoptotic cell death in the HCT116 human colon cancer cell line

(2017) Kensuke Nishi et al.   Cell Death & Disease

Proteomic profiling of antibody-inducing immunogens in tumor tissue identifies PSMA1, LAP3, ANXA3, and maspin as colon cancer markers

(2017) Qian Yang et al.   Oncotarget

In Situ Ratiometric Quantitative Tracing of Intracellular Leucine Aminopeptidase Activity via an Activatable Near-Infrared Fluorescent Probe

(2016) Kaizhi Gu et al.   ACS Applied Materials & Interfaces

Activatable Photosensitizers: Agents for Selective Photodynamic Therapy

(2016) Xingshu Li et al.   ADVANCED FUNCTIONAL MATERIALS

Leucine aminopeptidase may contribute to the intrinsic resistance of cancer cells toward cisplatin as revealed by an ultrasensitive fluorescent probe

(2016) Qiuyu Gong et al.   Chemical Science

An enzyme-activatable probe with a self-immolative linker for rapid and sensitive alkaline phosphatase detection and cell imaging through a cascade reaction

(2015) Hongmei Zhang et al.   CHEMICAL COMMUNICATIONS

Protein modification and maintenance systems as biomarkers of ageing

(2015) Valerie Vanhooren et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The role of photodynamic therapy in overcoming cancer drug resistance

(2015) Bryan Q. Spring et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Overexpression of leucine aminopeptidase 3 contributes to malignant development of human esophageal squamous cell carcinoma

(2014) Shu Zhang et al.   JOURNAL OF MOLECULAR HISTOLOGY

Rational Design of Highly Sensitive Fluorescence Probes for Protease and Glycosidase Based on Precisely Controlled Spirocyclization

(2012) Masayo Sakabe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small-molecule probe using dual signals to monitor leucine aminopeptidase activity

(2011) Hey Young Yoon et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Activatable Photosensitizers for Imaging and Therapy

(2010) Jonathan F. Lovell et al.   CHEMICAL REVIEWS

Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization

(2010) Jonathan P. Celli et al.   CHEMICAL REVIEWS

Novel and highly sensitive fluorescent assay for leucine aminopeptidases

(2009) Huazhang Huang et al.   ANALYTICAL BIOCHEMISTRY