The role of photodynamic therapy in overcoming cancer drug resistance

Verteporfin-based photodynamic therapy overcomes gemcitabine insensitivity in a panel of pancreatic cancer cell lines

(2015) Jonathan P. Celli et al.   LASERS IN SURGERY AND MEDICINE

Phase I/II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer

(2014) M T Huggett et al.   BRITISH JOURNAL OF CANCER

Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia

(2014) Rakesh K. Jain   CANCER CELL

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

(2014) Berna C. Özdemir et al.   CANCER CELL

Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma

(2014) Andrew D. Rhim et al.   CANCER CELL

Development of photodynamic therapy regimens that control primary tumor growth and inhibit secondary disease

(2014) Madeeha Shams et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Low-dose angiostatic tyrosine kinase inhibitors improve photodynamic therapy for cancer: lack of vascular normalization

(2014) Andrea Weiss et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cellular Intrinsic Factors Involved in the Resistance of Squamous Cell Carcinoma to Photodynamic Therapy

(2014) Yolanda Gilaberte et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Light-Triggered, Efficient Cytosolic Release of IM7-Saporin Targeting the Putative Cancer Stem Cell Marker CD44 by Photochemical Internalization

(2014) Monica Bostad et al.   MOLECULAR PHARMACEUTICS

Photodynamic Therapy with 5-Aminolevulinic acid (ALA) Impairs Tumor Initiating and Chemo-Resistance Property in Head and Neck Cancer-Derived Cancer Stem Cells

(2014) Chuan-Hang Yu et al.   PLoS One

Selective treatment and monitoring of disseminated cancer micrometastases in vivo using dual-function, activatable immunoconjugates

(2014) B. Q. Spring et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics

(2014) Meenakshi Upreti et al.   Translational Oncology

Two combined photosensitizers: a goal for more effective photodynamic therapy of cancer

(2014) P Acedo et al.   Cell Death & Disease

Porphyrin–phospholipid liposomes permeabilized by near-infrared light

(2014) Kevin A. Carter et al.   Nature Communications

Three-layered polyplex micelle as a multifunctional nanocarrier platform for light-induced systemic gene transfer

(2014) Takahiro Nomoto et al.   Nature Communications

Inhibition of c-Met Reduces Lymphatic Metastasis in RIP-Tag2 Transgenic Mice

(2013) B. Sennino et al.   CANCER RESEARCH

Photophysics of Silicon Phthalocyanines in Aqueous Media

(2013) Tennyson L. Doane et al.   CHEMPHYSCHEM

Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties

(2013) Monica Bostad et al.   JOURNAL OF CONTROLLED RELEASE

The benefits of photodynamic therapy on vertebral bone are maintained and enhanced by combination treatment with bisphosphonates and radiation therapy

(2013) Victor C. K. Lo et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Bax Exists in a Dynamic Equilibrium between the Cytosol and Mitochondria to Control Apoptotic Priming

(2013) Barbara Schellenberg et al.   MOLECULAR CELL

Acquisition of paclitaxel resistance via PI3K-dependent epithelial-mesenchymal transition in A2780 human ovarian cancer cells

(2013) FANGFANG DU et al.   ONCOLOGY REPORTS

Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules

(2013) I. Rizvi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The novel c-Met inhibitor cabozantinib overcomes gemcitabine resistance and stem cell signaling in pancreatic cancer

(2013) C Hage et al.   Cell Death & Disease

Markedly Enhanced Permeability and Retention Effects Induced by Photo-immunotherapy of Tumors

(2012) Kohei Sano et al.   ACS Nano

EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer

(2012) Alexandria M Haslehurst et al.   BMC CANCER

Photoimmunotherapy and Irradiance Modulation Reduce Chemotherapy Cycles and Toxicity in a Murine Model for Ovarian Carcinomatosis: Perspective and Results

(2012) Imran Rizvi et al.   ISRAEL JOURNAL OF CHEMISTRY

Strongly amphiphilic photosensitizers are not substrates of the cancer stem cell marker ABCG2 and provides specific and efficient light-triggered drug delivery of an EGFR-targeted cytotoxic drug

(2012) Pål Kristian Selbo et al.   JOURNAL OF CONTROLLED RELEASE

Abstract A127: Combination therapy targeting EGFR/MET crosstalk using nanotechnology improves photodynamic therapy treatment of pancreatic cancer

(2012) L. Z. Zheng et al.   MOLECULAR CANCER THERAPEUTICS

Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors

(2012) Timothy R. Wilson et al.   NATURE

MET: a promising anticancer therapeutic target

(2012) Solange Peters et al.   Nature Reviews Clinical Oncology

Photodynamic Mechanisms induced by a Combination of Hypericin and a Chlorin Based-Photosensitizer in Head and Neck Squamous Cell Carcinoma Cells

(2012) Emina Besic Gyenge et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Overcoming Multidrug Resistance via Photodestruction of ABCG2-Rich Extracellular Vesicles Sequestering Photosensitive Chemotherapeutics

(2012) Vicky Goler-Baron et al.   PLoS One

Human ovarian cancer stem/progenitor cells are stimulated by doxorubicin but inhibited by Mullerian inhibiting substance

(2012) K. Meirelles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppression of Tumor Invasion and Metastasis by Concurrent Inhibition of c-Met and VEGF Signaling in Pancreatic Neuroendocrine Tumors

(2012) Barbara Sennino et al.   Cancer Discovery

Photodynamic therapy augments the efficacy of oncolytic vaccinia virus against primary and metastatic tumours in mice

(2011) M Gil et al.   BRITISH JOURNAL OF CANCER

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Mechanisms of Resistance to Photodynamic Therapy

(2011) A. Casas et al.   CURRENT MEDICINAL CHEMISTRY

Angiostatic kinase inhibitors to sustain photodynamic angio-occlusion

(2011) Patrycja Nowak-Sliwinska et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

(2011) Jonathan F. Lovell et al.   NATURE MATERIALS

Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

(2011) Makoto Mitsunaga et al.   NATURE MEDICINE

FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer

(2011) Thierry Conroy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Killing Hypoxic Cell Populations in a 3D Tumor Model with EtNBS-PDT

(2011) Conor L. Evans et al.   PLoS One

Stromal Endothelial Cells Directly Influence Cancer Progression

(2011) J. W. Franses et al.   Science Translational Medicine

Vascular regrowth following photodynamic therapy in the chicken embryo chorioallantoic membrane

(2010) Patrycja Nowak-Sliwinska et al.   ANGIOGENESIS

Assessing autophagy in the context of photodynamic therapy

(2010) John J. Reiners et al.   Autophagy

Bcl-2 proteins and mitochondria—Specificity in membrane targeting for death

(2010) Jennefer Lindsay et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ki-67 as a Molecular Target for Therapy in an In vitro Three-Dimensional Model for Ovarian Cancer

(2010) R. Rahmanzadeh et al.   CANCER RESEARCH

Synergistic Enhancement of Carboplatin Efficacy with Photodynamic Therapy in a Three-Dimensional Model for Micrometastatic Ovarian Cancer

(2010) I. Rizvi et al.   CANCER RESEARCH

Activatable Photosensitizers for Imaging and Therapy

(2010) Jonathan F. Lovell et al.   CHEMICAL REVIEWS

Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization

(2010) Jonathan P. Celli et al.   CHEMICAL REVIEWS

Patterns and Timing of Recurrence After Temozolomide-Based Chemoradiation for Glioblastoma

(2010) Michael T. Milano et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Substrate Affinity of Photosensitizers Derived from Chlorophyll-a: The ABCG2 Transporter Affects the Phototoxic Response of Side Population Stem Cell-like Cancer Cells to Photodynamic Therapy

(2010) Janet Morgan et al.   MOLECULAR PHARMACEUTICS

Understanding resistance to EGFR inhibitors—impact on future treatment strategies

(2010) Deric L. Wheeler et al.   Nature Reviews Clinical Oncology

A new protocol in photodynamic therapy: enhanced tumour cell death by combining two different photosensitizers

(2010) Angeles Villanueva et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Photochemical internalization (PCI) in cancer therapy: From bench towards bedside medicine

(2009) Ole-Jacob Norum et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Hypericin and 5-aminolevulinic acid-induced protoporphyrin IX induce enhanced phototoxicity in human endometrial cancer cells with non-coherent white light

(2009) Xiaoye Schneider-Yin et al.   Photodiagnosis and Photodynamic Therapy

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

In vivo Optical Molecular Imaging of Vascular Endothelial Growth Factor for Monitoring Cancer Treatment

(2008) S. K. Chang et al.   CLINICAL CANCER RESEARCH

Combination of Photodynamic Therapy with Anti-Cancer Agents

(2008) M.-F. Zuluaga et al.   CURRENT MEDICINAL CHEMISTRY