Identification of long-lived proteins in the mitochondria reveals increased stability of the electron transport chain

Generation and Release of Mitochondrial-Derived Vesicles in Health, Aging and Disease

(2020) Anna Picca et al.   Journal of Clinical Medicine

Quality control of the mitochondrial proteome

(2020) Jiyao Song et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons

(2019) Simon T. Schafer et al.   NATURE NEUROSCIENCE

The proteostasis network and its decline in ageing

(2019) Mark S. Hipp et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Age Mosaicism across Multiple Scales in Adult Tissues

(2019) Rafael Arrojo e Drigo et al.   Cell Metabolism

Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress

(2019) Abigail Buchwalter et al.   eLife

The basic machineries for mitochondrial protein quality control

(2019) Carmela Vazquez-Calvo et al.   MITOCHONDRION

Mitochondrial Supercomplexes Do Not Enhance Catalysis by Quinone Channeling

(2018) Justin G. Fedor et al.   Cell Metabolism

Mitochondrial Proteostasis in the Context of Cellular and Organismal Health and Aging

(2018) Erica A Moehle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systematic analysis of protein turnover in primary cells

(2018) Toby Mathieson et al.   Nature Communications

Mechanisms of mitophagy in cellular homeostasis, physiology and pathology

(2018) Konstantinos Palikaras et al.   NATURE CELL BIOLOGY

Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells

(2018) Brandon H. Toyama et al.   JOURNAL OF CELL BIOLOGY

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions

(2018) Eugenio F. Fornasiero et al.   Nature Communications

Human COX7A2L Regulates Complex III Biogenesis and Promotes Supercomplex Organization Remodeling without Affecting Mitochondrial Bioenergetics

(2018) Teresa Lobo-Jarne et al.   Cell Reports

The mitochondrial UPR: mechanisms, physiological functions and implications in ageing

(2017) Tomer Shpilka et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain

(2017) James A Letts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain

(2017) James A Letts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure and function of mitochondrial complex I

(2016) Christophe Wirth et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mammalian Heat Shock Response and Mechanisms Underlying Its Genome-wide Transcriptional Regulation

(2016) Dig B. Mahat et al.   MOLECULAR CELL

The architecture of respiratory supercomplexes

(2016) James A. Letts et al.   NATURE

The architecture of the mammalian respirasome

(2016) Jinke Gu et al.   NATURE

Mechanism of super-assembly of respiratory complexes III and IV

(2016) Sara Cogliati et al.   NATURE

Extracting Accurate Precursor Information for Tandem Mass Spectra by RawConverter

(2015) Lin He et al.   ANALYTICAL CHEMISTRY

Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts

(2015) Jon Sin et al.   Autophagy

Respiratory chain protein turnover rates in mice are highly heterogeneous but strikingly conserved across tissues, ages, and treatments

(2015) Pabalu P. Karunadharma et al.   FASEB JOURNAL

ProLuCID: An improved SEQUEST-like algorithm with enhanced sensitivity and specificity

(2015) T. Xu et al.   Journal of Proteomics

A Review of Color Blindness for Microscopists: Guidelines and Tools for Accommodating and Coping with Color Vision Deficiency

(2015) Douglas R. Keene   MICROSCOPY AND MICROANALYSIS

Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness

(2015) P. Katajisto et al.   SCIENCE

A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging

(2015) Jing Su et al.   Skeletal Muscle

LON is the master protease that protects against protein aggregation in human mitochondria through direct degradation of misfolded proteins

(2015) Ayenachew Bezawork-Geleta et al.   Scientific Reports

Census 2: isobaric labeling data analysis

(2014) Sung Kyu Robin Park et al.   BIOINFORMATICS

A Computational Algorithm to Predict shRNA Potency

(2014) Simon R.V. Knott et al.   MOLECULAR CELL

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures

(2013) Brandon H. Toyama et al.   CELL

Satellite Cells and the Muscle Stem Cell Niche

(2013) Hang Yin et al.   PHYSIOLOGICAL REVIEWS

An Optimized microRNA Backbone for Effective Single-Copy RNAi

(2013) Christof Fellmann et al.   Cell Reports

Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolism

(2012) Matthew L. Steinhauser et al.   NATURE

Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia

(2012) Duan-Sun Zhang et al.   NATURE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Protein homeostasis: live long, won't prosper

(2012) Brandon H. Toyama et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

OXPHOS Supercomplexes as a Hallmark of the Mitochondrial Phenotype of Adipogenic Differentiated Human MSCs

(2012) Andreas D. Hofmann et al.   PLoS One

Extremely Long-Lived Nuclear Pore Proteins in the Rat Brain

(2012) J. N. Savas et al.   SCIENCE

Analysis of proteome dynamics in the mouse brain

(2010) J. C. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans

(2010) Della C. David et al.   PLOS BIOLOGY

Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells

(2009) Maximiliano A. D'Angelo et al.   CELL

Heterogeneity of Mitochondria and Mitochondrial Function within Cells as Another Level of Mitochondrial Complexity

(2009) Andrey Kuznetsov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research

(2008) Yuen-Ting Cheung et al.   NEUROTOXICOLOGY