S100A8/A9 in COVID-19 pathogenesis: Impact on clinical outcomes

Serum calprotectin as a novel biomarker for severity of COVID-19 disease

(2021) Tezcan Kaya et al.   IRISH JOURNAL OF MEDICAL SCIENCE

Provisional Mortality Data — United States, 2020

(2021) Farida B. Ahmad et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study

(2020) Xiaobo Yang et al.   Lancet Respiratory Medicine

Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan. A Retrospective Observational Study

(2020) Yingzhen Du et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients

(2020) Hong-Yi Zheng et al.   Cellular & Molecular Immunology

Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis

(2020) Brandon Michael Henry et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China

(2020) Chuan Qin et al.   CLINICAL INFECTIOUS DISEASES

Faecal calprotectin indicates intestinal inflammation in COVID-19

(2020) Maria Effenberger et al.   GUT

Immunology of COVID-19: current state of the science

(2020) Nicolas Vabret et al.   IMMUNITY

S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis

(2020) Ninecia R. Scott et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil-to-lymphocyte ratio as an independent risk factor for mortality in hospitalized patients with COVID-19

(2020) Yuwei Liu et al.   JOURNAL OF INFECTION

Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2: A systematic review and meta-analysis

(2020) Yinghao Cao et al.   JOURNAL OF MEDICAL VIROLOGY

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China

(2020) Chaomin Wu et al.   JAMA Internal Medicine

Severe COVID-19 is marked by a dysregulated myeloid cell compartment

(2020) Jonas Schulte-Schrepping et al.   CELL

Elevated calprotectin and abnormal myeloid cell subsets discriminate severe from mild COVID-19

(2020) Aymeric Silvin et al.   CELL

Elevated serum levels of S100A8/A9 and HMGB1 at hospital admission are correlated with inferior clinical outcomes in COVID-19 patients

(2020) Liting Chen et al.   Cellular & Molecular Immunology

Biomarkers associated with COVID-19 disease progression

(2020) Giovanni Ponti et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Circulating levels of GDF-15 and calprotectin for prediction of in-hospital mortality in COVID-19 patients: a case series

(2020) Luis García de GuadianaRomualdo et al.   JOURNAL OF INFECTION

A single-cell atlas of the peripheral immune response in patients with severe COVID-19

(2020) Aaron J. Wilk et al.   NATURE MEDICINE

Clinical characteristics of 82 cases of death from COVID-19

(2020) Bicheng Zhang et al.   PLoS One

Comprehensive mapping of immune perturbations associated with severe COVID-19

(2020) Leticia Kuri-Cervantes et al.   Science Immunology

Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19

(2020) Qirui Guo et al.   Cell Host & Microbe

Outcome prediction by serum calprotectin in patients with COVID-19 in the emergency department

(2020) Wolfgang Bauer et al.   JOURNAL OF INFECTION

Decreased Fecal Calprotectin Levels in Cystic Fibrosis Patients After Antibiotic Treatment for Respiratory Exacerbation

(2019) Zeev Schnapp et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Signaling mechanisms inducing hypo-responsiveness of phagocytes during systemic inflammation

(2019) Nicole Freise et al.   BLOOD

S100A8/A9 in Inflammation

(2018) Siwen Wang et al.   Frontiers in Immunology

Danger-Associated Molecular Patterns (DAMPs): the Derivatives and Triggers of Inflammation

(2018) Seema Patel   CURRENT ALLERGY AND ASTHMA REPORTS

Current and future developments in the treatment of virus-induced hypercytokinemia

(2017) Jonathan P Wong et al.   Future Medicinal Chemistry

Severe disease in Cystic Fibrosis and fecal calprotectin levels

(2017) Giuseppe Fabio Parisi et al.   IMMUNOBIOLOGY

Alarmins and immunity

(2017) De Yang et al.   IMMUNOLOGICAL REVIEWS

The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype

(2016) A. A. Basiorka et al.   BLOOD

Calprotectin in rheumatic diseases

(2016) Francesca Ometto et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis

(2015) R F Schelbergen et al.   ANNALS OF THE RHEUMATIC DISEASES

Hepatoma derived growth factor (HDGF) dynamics in ovarian cancer cells

(2015) Karuna Giri et al.   APOPTOSIS

Human S100A9 potentiates IL-8 production in response to GM-CSF or fMLP via activation of a different set of transcription factors in neutrophils

(2014) Jean-Christophe Simard et al.   FEBS LETTERS

Alarmins MRP8 and MRP14 Induce Stress Tolerance in Phagocytes under Sterile Inflammatory Conditions

(2014) Judith Austermann et al.   Cell Reports

S100A8/A9 Proteins Mediate Neutrophilic Inflammation and Lung Pathology during Tuberculosis

(2013) Radha Gopal et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Induction of myelodysplasia by myeloid-derived suppressor cells

(2013) Xianghong Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

High Levels of S100A8/A9 Proteins Aggravate Ventilator-Induced Lung Injury via TLR4 Signaling

(2013) Maria T. Kuipers et al.   PLoS One

Induction of nuclear factor-κB responses by the S100A9 protein is Toll-like receptor-4-dependent

(2012) Matteo Riva et al.   IMMUNOLOGY

Alarmins: awaiting a clinical response

(2012) James K. Chan et al.   JOURNAL OF CLINICAL INVESTIGATION

An Inflammation Loop Orchestrated by S100A9 and Calprotectin Is Critical for Development of Arthritis

(2012) Annabelle Cesaro et al.   PLoS One

Inflammation-associated S100 proteins: new mechanisms that regulate function

(2010) Jesse Goyette et al.   AMINO ACIDS

Sputum and serum calprotectin are useful biomarkers during CF exacerbation

(2010) R.D. Gray et al.   Journal of Cystic Fibrosis

Identification of Human S100A9 as a Novel Target for Treatment of Autoimmune Disease via Binding to Quinoline-3-Carboxamides

(2009) Per Björk et al.   PLOS BIOLOGY

Different expression ratio of S100A8/A9 and S100A12 in acute and chronic lung diseases

(2008) Eva Lorenz et al.   RESPIRATORY MEDICINE