Oligodendrocyte progenitor cell fate and function in development and disease

Preservation of a remote fear memory requires new myelin formation

(2020) Simon Pan et al.   NATURE NEUROSCIENCE

Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons

(2020) Corina Nagy et al.   NATURE NEUROSCIENCE

A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders

(2020) Devika Agarwal et al.   Nature Communications

Altered human oligodendrocyte heterogeneity in multiple sclerosis

(2019) Sarah Jäkel et al.   NATURE

Single-cell transcriptomic analysis of Alzheimer’s disease

(2019) Hansruedi Mathys et al.   NATURE

Molecular Control of Oligodendrocyte Development

(2019) Benayahu Elbaz et al.   TRENDS IN NEUROSCIENCES

A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation

(2019) Alexandra Grubman et al.   NATURE NEUROSCIENCE

Disruption of Oligodendrogenesis Impairs Memory Consolidation in Adult Mice

(2019) Patrick E. Steadman et al.   NEURON

Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination

(2019) Leslie Kirby et al.   Nature Communications

Oligodendrocytes as A New Therapeutic Target in Schizophrenia: From Histopathological Findings to Neuron-Oligodendrocyte Interaction

(2019) Florian J. Raabe et al.   Cells

m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination

(2019) Huan Xu et al.   NEURON

Axonal myelin decrease in the splenium in major depressive disorder

(2018) Matthew R. Williams et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia

(2018) Femke M. de Vrij et al.   MOLECULAR PSYCHIATRY

Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination

(2018) Zita Hubler et al.   NATURE

A novel m6A reader Prrc2a controls oligodendroglial specification and myelination

(2018) Rong Wu et al.   CELL RESEARCH

Human ESC-Derived Chimeric Mouse Models of Huntington’s Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation

(2018) Mikhail Osipovitch et al.   Cell Stem Cell

Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis

(2018) Ana Mendanha Falcão et al.   NATURE MEDICINE

Microstructural white matter alterations in preclinical Alzheimer’s disease detected using free water elimination diffusion tensor imaging

(2017) Andrew R. Hoy et al.   PLoS One

Extracellular cues influencing oligodendrocyte differentiation and (re)myelination

(2016) Natalie A. Wheeler et al.   EXPERIMENTAL NEUROLOGY

Predominant expression of Alzheimer’s disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts

(2016) Pierre De Rossi et al.   Molecular Neurodegeneration

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

(2015) Fadi J. Najm et al.   NATURE

Transcriptional and Epigenetic Regulation of Oligodendrocyte Development and Myelination in the Central Nervous System

(2015) Ben Emery et al.   Cold Spring Harbor Perspectives in Biology

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis

(2014) Feng Mei et al.   NATURE MEDICINE

Gene expression regulation mediated through reversible m6A RNA methylation

(2014) Ye Fu et al.   NATURE REVIEWS GENETICS

Neuronal Activity Promotes Oligodendrogenesis and Adaptive Myelination in the Mammalian Brain

(2014) E. M. Gibson et al.   SCIENCE

A regenerative approach to the treatment of multiple sclerosis

(2013) Vishal A. Deshmukh et al.   NATURE

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells

(2011) Fadi J Najm et al.   NATURE METHODS

Training induces changes in white-matter architecture

(2009) Jan Scholz et al.   NATURE NEUROSCIENCE

Alzheimer's disease as homeostatic responses to age-related myelin breakdown

(2009) George Bartzokis   NEUROBIOLOGY OF AGING