Benefit Profile of Thrombomodulin Alfa Combined with Antithrombin Concentrate in Patients with Sepsis-Induced Disseminated Intravascular Coagulation

Effects of Thrombomodulin in Reducing Lethality and Suppressing Neutrophil Extracellular Trap Formation in the Lungs and Liver in a Lipopolysaccharide-Induced Murine Septic Shock Model

(2021) Yu Kato et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Review: The Emerging Role of Neutrophil Extracellular Traps in Sepsis and Sepsis-Associated Thrombosis

(2021) Zhaoyuan Chen et al.   Frontiers in Cellular and Infection Microbiology

Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?

(2020) Michael Mazzeffi et al.   ANESTHESIA AND ANALGESIA

Prognosis and rescue therapy for sepsis-related severe thrombocytopenia in critically ill patients

(2020) Zhigang Zhou et al.   CYTOKINE

Current understanding and future implications of sepsis‐induced thrombocytopenia

(2020) Subash Ghimire et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation

(2019) Toshiaki Iba et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Significance of plasma fibrinogen level and antithrombin activity in sepsis: A multicenter cohort study using a cubic spline model

(2019) Tsunehiro Matsubara et al.   THROMBOSIS RESEARCH

Recombinant Thrombomodulin Suppresses Histone-Induced Neutrophil Extracellular Trap Formation

(2019) Binita Shrestha et al.   Frontiers in Immunology

Concomitant Versus Individual Administration of Antithrombin and Thrombomodulin for Sepsis-Induced Disseminated Intravascular Coagulation: A Nationwide Japanese Registry Study

(2018) Yutaka Umemura et al.   CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS

Microangiopathies thrombotiques secondaires

(2017) P. Coppo   REVUE DE MEDECINE INTERNE

Effects of combination therapy using antithrombin and thrombomodulin for sepsis-associated disseminated intravascular coagulation

(2017) Toshiaki Iba et al.   Annals of Intensive Care

Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients

(2016) T. A. M. Claushuis et al.   BLOOD

The efficacy and safety of antithrombin and recombinant human thrombomodulin combination therapy in patients with severe sepsis and disseminated intravascular coagulation

(2016) Norihisa Yasuda et al.   JOURNAL OF CRITICAL CARE

Thrombocytopenia in critically ill patients with severe sepsis/septic shock: Prognostic value and association with a distinct serum cytokine profile

(2016) Panagiotis Tsirigotis et al.   JOURNAL OF CRITICAL CARE

Is Thrombocytopenia an Early Prognostic Marker in Septic Shock?

(2015) Nadiejda Thiery-Antier et al.   CRITICAL CARE MEDICINE

Thrombocytopenia impairs host defense in gram-negative pneumonia-derived sepsis in mice

(2014) S. F. de Stoppelaar et al.   BLOOD

Recombinant human soluble thrombomodulin and mortality in severe pneumonia patients with sepsis-associated disseminated intravascular coagulation: an observational nationwide study

(2014) T. Tagami et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Antithrombin and mortality in severe pneumonia patients with sepsis-associated disseminated intravascular coagulation: an observational nationwide study

(2014) T. Tagami et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Impact of recombinant soluble thrombomodulin (thrombomodulin alfa) on disseminated intravascular coagulation

(2013) Jun Mimuro et al.   THROMBOSIS RESEARCH

The Frequency and Clinical Significance of Thrombocytopenia Complicating Critical Illness

(2010) Phil Hui et al.   CHEST

The Role of Natural Anticoagulants in the Pathogenesis and Management of Systemic Activation of Coagulation and Inflammation in Critically Ill Patients

(2008) Marcel Levi et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS