Thrombocytopenia impairs host defense in gram-negative pneumonia-derived sepsis in mice

Platelet Glycoprotein Ib-IX as a Regulator of Systemic Inflammation

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The role of platelets in sepsis

(2014) Cornelis van ’t Veer et al.   THROMBOSIS AND HAEMOSTASIS

Only severe thrombocytopenia results in bleeding and defective thrombus formation in mice

(2013) M. Morowski et al.   BLOOD

Activated Platelets Enhance IL-10 Secretion and Reduce TNF-  Secretion by Monocytes

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Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance

(2013) Connie H Y Wong et al.   NATURE IMMUNOLOGY

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protease activated receptor 4 limits bacterial growth and lung pathology during late stage Streptococcus pneumoniae induced pneumonia in mice

(2013) Cornelis van ’t Veer et al.   THROMBOSIS AND HAEMOSTASIS

Disruption of Platelet-derived Chemokine Heteromers Prevents Neutrophil Extravasation in Acute Lung Injury

(2012) Jochen Grommes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Platelets support a protective immune response to LCMV by preventing splenic necrosis

(2012) G. D. Loria et al.   BLOOD

Intravascular Neutrophil Extracellular Traps Capture Bacteria from the Bloodstream during Sepsis

(2012) Braedon McDonald et al.   Cell Host & Microbe

Platelets: key players in vascular inflammation

(2012) Delia Projahn et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Platelets Induce Apoptosis during Sepsis in a Contact-Dependent Manner That Is Inhibited by GPIIb/IIIa Blockade

(2012) Matthew Sharron et al.   PLoS One

Myeloid-Related Protein-14 Contributes to Protective Immunity in Gram-Negative Pneumonia Derived Sepsis

(2012) Ahmed Achouiti et al.   PLoS Pathogens

Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum

(2011) Adriana Vieira-de-Abreu et al.   Seminars in Immunopathology

Loss of Suppression of Tumorigenicity 2 (ST2) Gene Reverses Sepsis-induced Inhibition of Lung Host Defense in Mice

(2010) Jacobien J. Hoogerwerf et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Risk factors and pathogenic significance of severe sepsis and septic shock in 2286 patients with gram-negative bacteremia

(2010) Cheol-In Kang et al.   JOURNAL OF INFECTION

Critical care and the global burden of critical illness in adults

(2010) Neill KJ Adhikari et al.   LANCET

Sepsis Alters the Megakaryocyte–Platelet Transcriptional Axis Resulting in Granzyme B–mediated Lymphotoxicity

(2009) Robert J. Freishtat et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Platelets in defense against bacterial pathogens

(2009) Michael R. Yeaman   CELLULAR AND MOLECULAR LIFE SCIENCES

Platelets support pulmonary recruitment of neutrophils in abdominal sepsis*

(2009) Muhammad Asaduzzaman et al.   CRITICAL CARE MEDICINE

Beneficial effect of clopidogrel in a mouse model of polymicrobial sepsis

(2009) M. SEIDEL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Amicus or Adversary

(2008) Fernando A. Bozza et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Inflammation induces hemorrhage in thrombocytopenia

(2008) T. Goerge et al.   BLOOD

Host–pathogen interactions in sepsis

(2007) Tom van der Poll et al.   LANCET INFECTIOUS DISEASES