AtheroSpectrum Reveals Novel Macrophage Foam Cell Gene Signatures Associated With Atherosclerotic Cardiovascular Disease Risk

New Insights on the Role of Lipid Metabolism in the Metabolic Reprogramming of Macrophages

(2020) Ana Batista-Gonzalez et al.   Frontiers in Immunology

Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas

(2020) Alma Zernecke et al.   CIRCULATION RESEARCH

Challenges in unsupervised clustering of single-cell RNA-seq data

(2019) Vladimir Yu Kiselev et al.   NATURE REVIEWS GENETICS

Atherosclerosis

(2019) Peter Libby et al.   Nature Reviews Disease Primers

Single-cell immune landscape of human atherosclerotic plaques

(2019) Dawn M. Fernandez et al.   NATURE MEDICINE

Macrophages in Atherosclerosis Regression

(2019) Tessa J. Barrett   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibition of the NLRP3 inflammasome attenuates foam cell formation of THP-1 macrophages by suppressing ox-LDL uptake and promoting cholesterol efflux

(2018) Liang Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine AtherosclerosisNovelty and Significance

(2018) Clément Cochain et al.   CIRCULATION RESEARCH

Alternative macrophages in atherosclerosis: not always protective!

(2018) Benoit Pourcet et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of NLRP3 Inflammasome Promotes Foam Cell Formation in Vascular Smooth Muscle Cells and Atherogenesis Via HMGB1

(2018) Rui Wang et al.   Journal of the American Heart Association

Highlighting Residual Atherosclerotic Cardiovascular Disease Risk

(2018) Yunosuke Matsuura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models

(2018) Kyeongdae Kim et al.   CIRCULATION RESEARCH

Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression

(2017) Karishma Rahman et al.   JOURNAL OF CLINICAL INVESTIGATION

Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis

(2017) Yongmei Liu et al.   Nature Communications

Irgm1 promotes M1 but not M2 macrophage polarization in atherosclerosis pathogenesis and development

(2016) Shaohong Fang et al.   ATHEROSCLEROSIS

ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression

(2016) Binod Aryal et al.   Nature Communications

Lipids, lipoprotein distribution and depressive symptoms: the Multi-Ethnic Study of Atherosclerosis

(2016) K L Ong et al.   Translational Psychiatry

Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques

(2015) Anusha N. Seneviratne et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk

(2013) David C. Goff et al.   CIRCULATION

Identification of two genes potentially associated in iron-heme homeostasis in human carotid plaque using microarray analysis

(2013) Hanène Ayari et al.   JOURNAL OF BIOSCIENCES

Distribution of macrophage polarization markers in human atherosclerosis

(2012) J. Lauran Stöger et al.   ATHEROSCLEROSIS

Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses

(2012) Nathanael J. Spann et al.   CELL

Elevated CD14 ++ CD16 − Monocytes Predict Cardiovascular Events

(2012) Katarina E. Berg et al.   Circulation-Cardiovascular Genetics

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis

(2011) Anouk A.J. Hamers et al.   CIRCULATION RESEARCH

NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis

(2011) Richard N. Hanna et al.   CIRCULATION RESEARCH

Residual Cardiovascular Risk Despite Optimal LDL Cholesterol Reduction with Statins: The Evidence, Etiology, and Therapeutic Challenges

(2011) Uchechukwu K. Sampson et al.   Current Atherosclerosis Reports

Predictive Value of Brachial Flow-Mediated Dilation for Incident Cardiovascular Events in a Population-Based Study

(2009) Joseph Yeboah et al.   CIRCULATION

Vulnerable atherosclerotic plaque metalloproteinases and foam cell phenotypes

(2009) Andrew C. Newby et al.   THROMBOSIS AND HAEMOSTASIS

General Cardiovascular Risk Profile for Use in Primary Care

(2008) Ralph B. D’Agostino et al.   CIRCULATION