Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas

Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease

(2020) Yingyue Zhou et al.   NATURE MEDICINE

Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke

(2020) Yves Werner et al.   NATURE NEUROSCIENCE

TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge

(2020) Alicia A. Nugent et al.   NEURON

Single Cell RNA Sequencing in Atherosclerosis Research

(2020) Jesse W. Williams et al.   CIRCULATION RESEARCH

T cell subsets and functions in atherosclerosis

(2020) Ryosuke Saigusa et al.   Nature Reviews Cardiology

Immunity and Inflammation in Atherosclerosis

(2019) Dennis Wolf et al.   CIRCULATION RESEARCH

Response by Kim and Choi to Letter Regarding Article, “Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models”

(2019) Kyeongdae Kim et al.   CIRCULATION RESEARCH

Letter by Cochain et al Regarding Article, “Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models”

(2019) Clément Cochain et al.   CIRCULATION RESEARCH

Slide-seq: A scalable technology for measuring genome-wide expression at high spatial resolution

(2019) Samuel G. Rodriques et al.   SCIENCE

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

(2019) Svetoslav Chakarov et al.   SCIENCE

Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+

(2019) Chee-Huat Linus Eng et al.   NATURE

Cytokine Circuits in Cardiovascular Disease

(2019) Jesse W. Williams et al.   IMMUNITY

Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death

(2019) Carlos Silvestre-Roig et al.   NATURE

Biological Roles of Neutrophil-Derived Granule Proteins and Cytokines

(2019) Marco Antonio Cassatella et al.   TRENDS IN IMMUNOLOGY

Adventitial Cell Atlas of wt (Wild Type) and ApoE (Apolipoprotein E)-Deficient Mice Defined by Single-Cell RNA Sequencing

(2019) Wenduo Gu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

(2019) Diego Adhemar Jaitin et al.   CELL

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

(2019) Omar Khan et al.   NATURE

Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis

(2019) Robert C. Wirka et al.   NATURE MEDICINE

Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells

(2019) Zhaoyuan Liu et al.   CELL

From Focal Lipid Storage to Systemic Inflammation

(2019) Peter Libby et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis

(2019) Xuelian Xiong et al.   MOLECULAR CELL

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

(2019) Andrea Cossarizza et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Resolving the fibrotic niche of human liver cirrhosis at single-cell level

(2019) P. Ramachandran et al.   NATURE

Single-cell immune landscape of human atherosclerotic plaques

(2019) Dawn M. Fernandez et al.   NATURE MEDICINE

Fast, sensitive and accurate integration of single-cell data with Harmony

(2019) Ilya Korsunsky et al.   NATURE METHODS

Migratory and Dancing Macrophage Subsets in Atherosclerotic Lesions

(2019) Sara McArdle et al.   CIRCULATION RESEARCH

Type-I interferons in atherosclerosis

(2019) Hung-Jen Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immune cell census in murine atherosclerosis: cytometry by time of flight illuminates vascular myeloid cell diversity

(2018) Jennifer E Cole et al.   CARDIOVASCULAR RESEARCH

Regulatory CD4+T Cells Recognize MHC-II-Restricted Peptide Epitopes of Apolipoprotein B

(2018) Takayuki Kimura et al.   CIRCULATION

Natural Killer Cells at Ease

(2018) Holger Winkels et al.   CIRCULATION RESEARCH

Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine AtherosclerosisNovelty and Significance

(2018) Clément Cochain et al.   CIRCULATION RESEARCH

Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass CytometryNovelty and Significance

(2018) Holger Winkels et al.   CIRCULATION RESEARCH

Atherosclerosis in the single-cell era

(2018) Holger Winkels et al.   CURRENT OPINION IN LIPIDOLOGY

Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis

(2018) Dalia E. Gaddis et al.   Nature Communications

The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions

(2018) Zoltan Nagy et al.   BLOOD

Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models

(2018) Kyeongdae Kim et al.   CIRCULATION RESEARCH

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen

(2018) Hwee Ying Lim et al.   IMMUNITY

Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction

(2018) Sarah A. Dick et al.   NATURE IMMUNOLOGY

NKT cells in cardiovascular diseases

(2017) Gijs H.M. van Puijvelde et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C − Cells

(2017) Alexander Mildner et al.   IMMUNITY

Comparative Analysis of Single-Cell RNA Sequencing Methods

(2017) Christoph Ziegenhain et al.   MOLECULAR CELL

IRF3 and type I interferons fuel a fatal response to myocardial infarction

(2017) Kevin R King et al.   NATURE MEDICINE

Simultaneous epitope and transcriptome measurement in single cells

(2017) Marlon Stoeckius et al.   NATURE METHODS

Natural killer T cells in atherosclerosis

(2017) Godfrey S. Getz et al.   Nature Reviews Cardiology

Macrophages in vascular inflammation and atherosclerosis

(2017) Clement Cochain et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhighneutrophils

(2017) Camilla Engblom et al.   SCIENCE

Type-2 innate lymphoid cells control the development of atherosclerosis in mice

(2017) Stephen A. Newland et al.   Nature Communications

Perivascular Adipose Tissue Harbors Atheroprotective IgM-Producing B Cells

(2017) Prasad Srikakulapu et al.   Frontiers in Physiology

Key Features of Gamma-Delta T-Cell Subsets in Human Diseases and Their Immunotherapeutic Implications

(2017) Myriam Lawand et al.   Frontiers in Immunology

Genetic Depletion or Hyperresponsiveness of Natural Killer Cells Do Not Affect Atherosclerosis Development

(2017) Wared Nour-Eldine et al.   CIRCULATION RESEARCH

Artery Tertiary Lymphoid Organs Control Multilayered Territorialized Atherosclerosis B-Cell Responses in AgedApoE−/−MiceHighlights

(2016) Prasad Srikakulapu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

CCR5+T-bet+FoxP3+Effector CD4 T Cells Drive AtherosclerosisNovelty and Significance

(2016) Jie Li et al.   CIRCULATION RESEARCH

Macrophages and Dendritic Cells

(2016) Myron I. Cybulsky et al.   CIRCULATION RESEARCH

Atherosclerosis-Driven Treg Plasticity Results in Formation of a Dysfunctional Subset of Plastic IFNγ + Th1/TregsNovelty and Significance

(2016) Matthew J. Butcher et al.   CIRCULATION RESEARCH

Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6C low Monocytes while Preserving Macrophage Gene Function

(2016) Graham D. Thomas et al.   IMMUNITY

The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic Cells

(2016) Shinelle Menezes et al.   IMMUNITY

MHC II + resident peritoneal and pleural macrophages rely on IRF4 for development from circulating monocytes

(2016) Ki-Wook Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD8+T Cells Regulate Monopoiesis and Circulating Ly6ChighMonocyte Levels in Atherosclerosis in MiceNovelty and Significance

(2015) Clément Cochain et al.   CIRCULATION RESEARCH

Role of Lymphocytes in Myocardial Injury, Healing, and Remodeling After Myocardial Infarction

(2015) U. Hofmann et al.   CIRCULATION RESEARCH

Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β Receptors

(2015) Desheng Hu et al.   IMMUNITY

Emerging Functions of Amphiregulin in Orchestrating Immunity, Inflammation, and Tissue Repair

(2015) Dietmar M.W. Zaiss et al.   IMMUNITY

CXCR6 regulates the recruitment of pro-inflammatory IL-17A-producing T cells into atherosclerotic aortas

(2015) Matthew J. Butcher et al.   INTERNATIONAL IMMUNOLOGY

Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth

(2015) Sherine Ensan et al.   NATURE IMMUNOLOGY

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis

(2015) Laura S Shankman et al.   NATURE MEDICINE

A Change in Inflammatory Footprint Precedes Plaque Instability: A Systematic Evaluation of Cellular Aspects of the Adaptive Immune Response in Human Atherosclerosis

(2015) R. A. van Dijk et al.   Journal of the American Heart Association

Staging Lymphocyte Presence in Human Atherosclerosis: A Tale Told by Numbers

(2015) Erik A. L. Biessen et al.   Journal of the American Heart Association

γδ T Lymphocytes in the Diagnosis of Human T Cell Receptor Immunodeficiencies

(2015) Beatriz Garcillán et al.   Frontiers in Immunology

Cytotoxic CD8+ T Cells Stimulate Hematopoietic Progenitors by Promoting Cytokine Release from Bone Marrow Mesenchymal Stromal Cells

(2014) Christian M. Schürch et al.   Cell Stem Cell

Contribution of Intimal Smooth Muscle Cells to Cholesterol Accumulation and Macrophage-Like Cells in Human Atherosclerosis

(2014) Sima Allahverdian et al.   CIRCULATION

Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating T Helper-1 Adaptive Immunity

(2014) Ingo Hilgendorf et al.   CIRCULATION

Transdifferentiation of Vascular Smooth Muscle Cells to Macrophage-Like Cells During Atherogenesis

(2014) Susanne Feil et al.   CIRCULATION RESEARCH

Artery Tertiary Lymphoid Organs Contribute to Innate and Adaptive Immune Responses in Advanced Mouse Atherosclerosis

(2014) Sarajo Kumar Mohanta et al.   CIRCULATION RESEARCH

TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate

(2014) Shiori Ito et al.   CORONARY ARTERY DISEASE

Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice

(2014) Clare L. Abram et al.   JOURNAL OF IMMUNOLOGICAL METHODS

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

(2013) Leo M. Carlin et al.   CELL

Cytotoxic and Proinflammatory CD8 + T Lymphocytes Promote Development of Vulnerable Atherosclerotic Plaques in ApoE-Deficient Mice

(2013) Tin Kyaw et al.   CIRCULATION

Functional development of γδ T cells

(2013) Immo Prinz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Self-antigen-Driven Activation Induces Instability of Regulatory T Cells during an Inflammatory Autoimmune Response

(2013) Samantha L. Bailey-Bucktrout et al.   IMMUNITY

Minimal Differentiation of Classical Monocytes as They Survey Steady-State Tissues and Transport Antigen to Lymph Nodes

(2013) Claudia Jakubzick et al.   IMMUNITY

Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis

(2013) Roland Klingenberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Local proliferation dominates lesional macrophage accumulation in atherosclerosis

(2013) Clinton S Robbins et al.   NATURE MEDICINE

Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses

(2012) Nathanael J. Spann et al.   CELL

Regulation of Hematopoietic Stem and Progenitor Cell Mobilization by Cholesterol Efflux Pathways

(2012) Marit Westerterp et al.   Cell Stem Cell

Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype

(2012) Larissa Cardilo-Reis et al.   EMBO Molecular Medicine

CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis

(2012) Samira Tamoutounour et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Transcription Factor GATA-3 Controls Cell Fate and Maintenance of Type 2 Innate Lymphoid Cells

(2012) Thomas Hoyler et al.   IMMUNITY

Dynamic T cell–APC interactions sustain chronic inflammation in atherosclerosis

(2012) Ekaterina K. Koltsova et al.   JOURNAL OF CLINICAL INVESTIGATION

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(2012) Lasse Folkersen et al.   MOLECULAR MEDICINE

Transcription factor RORα is critical for nuocyte development

(2012) See Heng Wong et al.   NATURE IMMUNOLOGY

Innate Response Activator B Cells Protect Against Microbial Sepsis

(2012) P. J. Rauch et al.   SCIENCE

Dynamic Changes in Regulatory T Cells Are Linked to Levels of Diet-Induced Hypercholesterolemia

(2011) Elena Maganto-García et al.   CIRCULATION

B-Cell Aortic Homing and Atheroprotection Depend on Id3

(2011) Amanda C. Doran et al.   CIRCULATION RESEARCH

The many roles of TOX in the immune system

(2011) Parinaz Aliahmad et al.   CURRENT OPINION IN IMMUNOLOGY

Fascin1 Promotes Cell Migration of Mature Dendritic Cells

(2011) Y. Yamakita et al.   JOURNAL OF IMMUNOLOGY

The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C− monocytes

(2011) Richard N Hanna et al.   NATURE IMMUNOLOGY

CD11c/CD18 Expression Is Upregulated on Blood Monocytes During Hypertriglyceridemia and Enhances Adhesion to Vascular Cell Adhesion Molecule-1

(2010) R. Michael Gower et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

CD8+ T cell activation predominate early immune responses to hypercholesterolemia in Apoe-/- mice

(2010) Daniel Kolbus et al.   BMC IMMUNOLOGY

Invariant natural killer T cells: Linking inflammation and neovascularization in human atherosclerosis

(2010) Emmanouil Kyriakakis et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

(2010) L. Yvan-Charvet et al.   SCIENCE

Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-of-Flight Mass Spectrometry

(2009) Dmitry R. Bandura et al.   ANALYTICAL CHEMISTRY

NKT Cell Subsets Mediate Differential Proatherogenic Effects in ApoE −/− Mice

(2009) Kelly To et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Interleukin-17 and Interferon-γ Are Produced Concomitantly by Human Coronary Artery–Infiltrating T Cells and Act Synergistically on Vascular Smooth Muscle Cells

(2009) Raymond E. Eid et al.   CIRCULATION

Functional Role of CD11c + Monocytes in Atherogenesis Associated With Hypercholesterolemia

(2009) Huaizhu Wu et al.   CIRCULATION

Lymphotoxin β receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of agedApoE−/−mice

(2009) Rolf Gräbner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesions

(2009) Su-Ning Zhu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17–producing γδ T cell subsets

(2009) Julie C Ribot et al.   NATURE IMMUNOLOGY

Requirements for CD8 T-cell migration into the human arterial wall

(2008) Jan Gewaltig et al.   HUMAN PATHOLOGY