Polygenic risk scores and rheumatic diseases

Genetics of 35 blood and urine biomarkers in the UK Biobank

(2021) Nasa Sinnott-Armstrong et al.   NATURE GENETICS

The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation

(2021) Samuel A. Lambert et al.   NATURE GENETICS

Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups

(2021) Yong-Fei Wang et al.   Nature Communications

Improved prediction of fracture risk leveraging a genome-wide polygenic risk score

(2021) Tianyuan Lu et al.   Genome Medicine

Polygenic Risk Scores have high diagnostic capacity in ankylosing spondylitis

(2021) Zhixiu Li et al.   ANNALS OF THE RHEUMATIC DISEASES

Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity

(2020) Lingyan Chen et al.   HUMAN MOLECULAR GENETICS

Using genetics to prioritize diagnoses for rheumatology outpatients with inflammatory arthritis

(2020) Rachel Knevel et al.   Science Translational Medicine

Genomic Risk Score impact on susceptibility to systemic sclerosis

(2020) Lara Bossini-Castillo et al.   ANNALS OF THE RHEUMATIC DISEASES

MRI compared with low-dose CT scanning in the diagnosis of axial spondyloarthritis

(2019) Lusi Ye et al.   CLINICAL RHEUMATOLOGY

Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients

(2018) Matthew T. Patrick et al.   Nature Communications

A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk

(2013) Annie Yarwood et al.   ANNALS OF THE RHEUMATIC DISEASES

Power and Predictive Accuracy of Polygenic Risk Scores

(2013) Frank Dudbridge   PLoS Genetics

Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk

(2009) David M. Evans et al.   HUMAN MOLECULAR GENETICS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE