Efficient Decarboxylative/Defluorinative Alkylation for the Synthesis of gem ‐Difluoroalkenes through an S N 2 ’‐Type Route

Pd/Cu‐Catalyzed Defluorinative Carbonylative Coupling of Aryl Iodides and gem ‐Difluoroalkenes: Efficient Synthesis of α‐Fluorochalcones

(2021) Fu‐Peng Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-Selective Defluorinative sp3 C–H Alkylation of Secondary Amides

(2021) Wen-Jun Yue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemoselective catalytic hydrodefluorination of trifluoromethylalkenes towards mono-/gem-di-fluoroalkenes under metal-free conditions

(2021) Jingjing Zhang et al.   Nature Communications

Chromium-Catalyzed Allylic Defluorinative Ketyl Olefin Coupling

(2021) Chang Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

3,3-Difluoroallyl ammonium salts: highly versatile, stable and selective gem-difluoroallylation reagents

(2021) Fei Ye et al.   Nature Communications

Modern strategies for C–H functionalization of heteroarenes with alternative coupling partners

(2021) Binlin Zhao et al.   Chem

NiH-Catalyzed Migratory Defluorinative Olefin Cross-Coupling: Trifluoromethyl-Substituted Alkenes as Acceptor Olefins to Form gem -Difluoroalkenes

(2020) Fenglin Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalyzing the Hydrodefluorination of CF3-Substituted Alkenes by PhSiH3. H• Transfer from a Nickel Hydride

(2020) Chengbo Yao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Palladium‐Catalyzed C−F Bond Alkynylation of Tetrasubstituted gem ‐Difluoroalkenes

(2020) Qiao Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition‐Metal‐Free Carbon Isotope Exchange of Phenyl Acetic Acids

(2020) Gianluca Destro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Methodologies and Strategies for Selective Borylation of C–Het and C–C Bonds

(2020) Minyan Wang et al.   CHEMICAL REVIEWS

Direct reversible decarboxylation from stable organic acids in dimethylformamide solution

(2020) Duanyang Kong et al.   SCIENCE

Design and Synthesis of TY‐Phos and Application in Palladium‐Catalyzed Enantioselective Fluoroarylation of gem ‐Difluoroalkenes

(2020) Tao‐Yan Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Migratory functionalization of unactivated alkyl bromides for construction of all-carbon quaternary centers via transposed tert-C-radicals

(2020) Chuan Zhu et al.   Nature Communications

Manganese-mediated reductive functionalization of activated aliphatic acids and primary amines

(2020) Zhan Li et al.   Nature Communications

Catalytic Enantioselective Allylic C–F Bond Functionalization

(2020) Minyan Wang et al.   CHEMISTRY LETTERS

Photocatalytic decarboxylative alkylations mediated by triphenylphosphine and sodium iodide

(2019) Ming-Chen Fu et al.   SCIENCE

Open-Air Alkylation Reactions in Photoredox-Catalyzed DNA-Encoded Library Synthesis

(2019) James P. Phelan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoredox-Coupled F-Nucleophilic Addition: Allylation of gem -Difluoroalkenes

(2019) Haidong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition‐Metal‐Free Defluorosilylation of Fluoroalkenes with Silylboronates

(2019) Pan Gao et al.   CHINESE JOURNAL OF CHEMISTRY

Direct Catalytic Decarboxylative Amination of Aryl Acetic Acids

(2019) Duanyang Kong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Boryl and Silyl Substitution with Trifluoromethyl Alkenes: Scope, Utility, and Mechanistic Nuances of Cu–F β-Elimination

(2019) Paulo H. S. Paioti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal-Catalyzed Ionic Decarboxylative Cross-Coupling Reactions of C(sp3) Acids: Reaction Development, Mechanisms, and Application

(2019) Patrick J. Moon et al.   ACS Catalysis

Transition Metal-Mediated and -Catalyzed C-F Bond Activation via Fluorine Elimination

(2018) Takeshi Fujita et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Decarboxylative Benzylation of Aryl and Alkenyl Boronic Esters

(2018) Patrick J. Moon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

(2018) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly

(2018) Supakanya Wongrakpanich et al.   Aging and Disease

Decarboxylative sp3 C–N coupling via dual copper and photoredox catalysis

(2018) Yufan Liang et al.   NATURE

Direct Catalytic Enantioselective Benzylation from Aryl Acetic Acids

(2018) Patrick J. Moon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of gem-Difluoroalkenes via Nickel-Catalyzed Reductive C–F and C–O Bond Cleavage

(2018) Zhiyang Lin et al.   ACS Catalysis

Copper-Catalyzed Regioselective Monodefluoroborylation of Polyfluoroalkenes en Route to Diverse Fluoroalkenes

(2017) Hironobu Sakaguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Defluorinative Reductive Cross-Coupling of gem-Difluoroalkenes with Unactivated Secondary and Tertiary Alkyl Halides

(2017) Xi Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoinduced decarboxylative borylation of carboxylic acids

(2017) Alexander Fawcett et al.   SCIENCE

Decarboxylative borylation

(2017) Chao Li et al.   SCIENCE

Synthesis of Functionalized gem-Difluoroalkenes via a Photocatalytic Decarboxylative/Defluorinative Reaction

(2016) Tiebo Xiao et al.   JOURNAL OF ORGANIC CHEMISTRY

Ambient Decarboxylative Arylation of Malonate Half-Esters via Oxidative Catalysis

(2016) Patrick J. Moon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

gem-Difluoroolefination of Diazo Compounds with TMSCF3 or TMSCF2Br: Transition-Metal-Free Cross-Coupling of Two Carbene Precursors

(2015) Mingyou Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Chemo- and Regioselective Decarboxylative Addition of β-Ketoacids to Allenes: Efficient Construction of Tertiary and Quaternary Carbon Centers

(2014) Changkun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unified Strategy to Monoterpene Indole Alkaloids: Total Syntheses of (±)-Goniomitine, (±)-1,2-Dehydroaspidospermidine, (±)-Aspidospermidine, (±)-Vincadifformine, and (±)-Kopsihainanine A

(2014) Olivier Wagnières et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Clean and Selective Radical Homocoupling Employing Carboxylic Acids with Titania Photoredox Catalysis

(2014) David W. Manley et al.   ORGANIC LETTERS

Substitution of Two Fluorine Atoms in a Trifluoromethyl Group: Regioselective Synthesis of 3-Fluoropyrazoles

(2012) Kohei Fuchibe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of α-Aryl Nitriles through Palladium-Catalyzed Decarboxylative Coupling of Cyanoacetate Salts with Aryl Halides and Triflates

(2011) Rui Shang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Decarboxylative coupling reactions: a modern strategy for C–C-bond formation

(2011) Nuria Rodríguez et al.   CHEMICAL SOCIETY REVIEWS

Palladium-Catalyzed Decarboxylative Couplings of 2-(2-Azaaryl)acetates with Aryl Halides and Triflates

(2010) Rui Shang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY