X-linked histone H3K27 demethylase Kdm6a regulates sexually dimorphic differentiation of hypothalamic neurons

JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells

(2020) Yongli Shan et al.   Nature Communications

Genes that escape from X‐chromosome inactivation: Potential contributors to Klinefelter syndrome

(2020) Maria Jose Navarro‐Cobos et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Role of PIWI-like 4 in modulating neuronal differentiation from human embryonal carcinoma cells

(2020) Charannya Sozheesvari Subhramanyam et al.   RNA Biology

Estradiol-dependent axogenesis and Ngn3 expression are determined by XY sex chromosome complement in hypothalamic neurons

(2020) Carla Daniela Cisternas et al.   Scientific Reports

UTX Regulates Human Neural Differentiation and Dendritic Morphology by Resolving Bivalent Promoters

(2020) Qing-Yuan Tang et al.   Stem Cell Reports

Differentiation of human pluripotent stem cells into neurons or cortical organoids requires transcriptional co-regulation by UTX and 53BP1

(2019) Xiaoyang Yang et al.   NATURE NEUROSCIENCE

Lysine demethylases KDM6A and UTY: The X and Y of histone demethylation

(2019) Iveta Gažová et al.   MOLECULAR GENETICS AND METABOLISM

Estradiol-Mediated Axogenesis of Hypothalamic Neurons Requires ERK1/2 and Ryanodine Receptors-Dependent Intracellular Ca2+ Rise in Male Rats

(2019) Lucas E. Cabrera Zapata et al.   Frontiers in Cellular Neuroscience

Molecular mechanisms and cellular events involved in the neuroprotective actions of estradiol. Analysis of sex differences

(2019) Iñigo Azcoitia et al.   FRONTIERS IN NEUROENDOCRINOLOGY

UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling

(2018) Xuepei Lei et al.   Stem Cell Reports

Kabuki syndrome: international consensus diagnostic criteria

(2018) Margaret P Adam et al.   JOURNAL OF MEDICAL GENETICS

Landscape of X chromosome inactivation across human tissues

(2017) Taru Tukiainen et al.   NATURE

UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome

(2017) Karl B. Shpargel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Histone H3K27 Demethylase UTX Regulates Synaptic Plasticity and Cognitive Behaviors in Mice

(2017) Gang-Bin Tang et al.   Frontiers in Molecular Neuroscience

Regulation of aromatase expression in the anterior amygdala of the developing mouse brain depends on ERβ and sex chromosome complement

(2017) Carla Daniela Cisternas et al.   Scientific Reports

Inhibition of KDM6 activity during murine ESC differentiation induces DNA damage

(2016) Christine Hofstetter et al.   JOURNAL OF CELL SCIENCE

The importance of having two X chromosomes

(2016) Arthur P. Arnold et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Sex-specific silencing of X-linked genes by Xist RNA

(2016) Srimonta Gayen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Escape Artists of the X Chromosome

(2016) Bradley P. Balaton et al.   TRENDS IN GENETICS

Oestradiol synthesized by female neurons generates sex differences in neuritogenesis

(2016) Isabel Ruiz-Palmero et al.   Scientific Reports

Mutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt Signaling

(2015) Lot Snijders Blok et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Biology and Evolution of Mammalian Y Chromosomes

(2015) Jennifer F. Hughes et al.   Annual Review of Genetics

Kabuki syndrome genesKMT2DandKDM6A: functional analyses demonstrate critical roles in craniofacial, heart and brain development

(2015) Peter M. Van Laarhoven et al.   HUMAN MOLECULAR GENETICS

X-chromosome inactivation and escape

(2015) CHRISTINE M. DISTECHE et al.   JOURNAL OF GENETICS

Sex chromosome complement determines sex differences in aromatase expression and regulation in the stria terminalis and anterior amygdala of the developing mouse brain

(2015) Carla D. Cisternas et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Escape from X Inactivation Varies in Mouse Tissues

(2015) Joel B. Berletch et al.   PLoS Genetics

Individuality and Variation of Personal Regulomes in Primary Human T Cells

(2015) Kun Qu et al.   Cell Systems

Variable escape from X-chromosome inactivation: Identifying factors that tip the scales towards expression

(2014) Samantha B. Peeters et al.   BIOESSAYS

Identification of sexually dimorphic genes in the neonatal mouse cortex and hippocampus

(2014) Chris Armoskus et al.   BRAIN RESEARCH

Human UTY(KDM6C) Is a Male-specificNϵ-Methyl Lysyl Demethylase

(2014) Louise J. Walport et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurogenin3 Restricts Serotonergic Neuron Differentiation to the Hindbrain

(2014) A. L. Carcagno et al.   JOURNAL OF NEUROSCIENCE

A new mathematical function to evaluate neuronal morphology using the Sholl analysis

(2014) Luis Miguel Garcia-Segura et al.   JOURNAL OF NEUROSCIENCE METHODS

Neurogenin 3 mediates sex chromosome effects on the generation of sex differences in hypothalamic neuronal development

(2014) María J. Scerbo et al.   Frontiers in Cellular Neuroscience

Effect of sex chromosome complement on sodium appetite and Fos-immunoreactivity induced by sodium depletion

(2013) Florencia M. Dadam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

X-Inactivation, Imprinting, and Long Noncoding RNAs in Health and Disease

(2013) Jeannie T. Lee et al.   CELL

RNA Helicase DDX3 Is a Regulatory Subunit of Casein Kinase 1 in Wnt- -Catenin Signaling

(2013) C.-M. Cruciat et al.   SCIENCE

Analysis of expressed SNPs identifies variable extents of expression from the human inactive X chromosome

(2013) Allison M Cotton et al.   GENOME BIOLOGY

Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes

(2012) J. T. Wolstenholme et al.   GENES BRAIN AND BEHAVIOR

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

(2012) Laurens Kruidenier et al.   NATURE

X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner

(2012) G. G. Welstead et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UTX and UTY Demonstrate Histone Demethylase-Independent Function in Mouse Embryonic Development

(2012) Karl B. Shpargel et al.   PLoS Genetics

Escape from X inactivation in mice and humans

(2012) Joel B Berletch et al.   GENOME BIOLOGY

Genetics and epigenetics of the X chromosome

(2011) Céline Morey et al.   Annals of the New York Academy of Sciences

Sexual differentiation of the human brain: Relation to gender identity, sexual orientation and neuropsychiatric disorders

(2011) Ai-Min Bao et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Sex differences in juvenile mouse social behavior are influenced by sex chromosomes and social context

(2011) K. H. Cox et al.   GENES BRAIN AND BEHAVIOR

Notch/Neurogenin 3 Signalling is Involved in the Neuritogenic Actions of Oestradiol in Developing Hippocampal Neurones

(2011) I. Ruiz-Palmero et al.   JOURNAL OF NEUROENDOCRINOLOGY

Molecular mechanisms involved in the regulation of neuritogenesis by estradiol: Recent advances

(2011) María Angeles Arevalo et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

A Motif Unique to the Human Dead-Box Protein DDX3 Is Important for Nucleic Acid Binding, ATP Hydrolysis, RNA/DNA Unwinding and HIV-1 Replication

(2011) Anna Garbelli et al.   PLoS One

Formin1 Mediates the Induction of Dendritogenesis and Synaptogenesis by Neurogenin3 in Mouse Hippocampal Neurons

(2011) Julia Simon-Areces et al.   PLoS One

Differential requirements for neurogenin 3 in the development of POMC and NPY neurons in the hypothalamus

(2010) Michelle Pelling et al.   DEVELOPMENTAL BIOLOGY

Global survey of escape from X inactivation by RNA-sequencing in mouse

(2010) F. Yang et al.   GENOME RESEARCH

Sex-Specific Differences in Expression of Histone Demethylases Utx and Uty in Mouse Brain and Neurons

(2008) J. Xu et al.   JOURNAL OF NEUROSCIENCE

Estradiol and the Developing Brain

(2008) MARGARET M. McCARTHY   PHYSIOLOGICAL REVIEWS

Developmental Expression and Regulation of Aromatase- and 5α-Reductase Type 1 mRNA in the Male and Female Mouse Hypothalamus

(2003) Magdalena Karolczak et al.   JOURNAL OF NEUROENDOCRINOLOGY