Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity

RNAscope CSF1 chromogenic in situ hybridization: a potentially useful tool in the differential diagnosis of tenosynovial giant cell tumors

(2021) Judith Jebastin Thangaiah et al.   HUMAN PATHOLOGY

Impact of Senescent Cell Subtypes on Tissue Dysfunction and Repair: Importance and Research Questions

(2021) Utkarsh Tripathi et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Transplanting cells from old but not young donors causes physical dysfunction in older recipients

(2020) Binsheng Wang et al.   AGING CELL

Size Does Matter: Litter Size Strongly Determines Adult Metabolism in Rodents

(2020) Marcela Parra-Vargas et al.   Cell Metabolism

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study

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Targeting senescent cells alleviates obesity‐induced metabolic dysfunction

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Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Acceleration of β Cell Aging Determines Diabetes and Senolysis Improves Disease Outcomes

(2019) Cristina Aguayo-Mazzucato et al.   Cell Metabolism

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease

(2019) LaTonya J. Hickson et al.   EBioMedicine

Cellular Senescence: Defining a Path Forward

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The integrative biology of type 2 diabetes

(2019) Michael Roden et al.   NATURE

Senolytics improve physical function and increase lifespan in old age

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Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue

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Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity

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JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age

(2015) Ming Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting senescent cells enhances adipogenesis and metabolic function in old age

(2015) Ming Xu et al.   eLife

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Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits

(2014) Nicole Heise et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Homeostasis and Effector Function of Lymphopenia-Induced "Memory-Like" T Cells in Constitutively T Cell-Depleted Mice

(2014) D. Voehringer et al.   JOURNAL OF IMMUNOLOGY

Cellular senescence: from physiology to pathology

(2014) Daniel Muñoz-Espín et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of NF-κB in the pathogenesis of diabetes and its associated complications

(2014) Sandip Patel et al.   Pharmacological Reports

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

Control of the senescence-associated secretory phenotype by NF- B promotes senescence and enhances chemosensitivity

(2011) Y. Chien et al.   GENES & DEVELOPMENT

Fat tissue, aging, and cellular senescence

(2010) Tamara Tchkonia et al.   AGING CELL

From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

(2009) R. A. DeFronzo   DIABETES

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Genetic background determines metabolic phenotypes in the mouse

(2008) Marie-France Champy et al.   MAMMALIAN GENOME

Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

(2008) Deborah M. Muoio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

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