A novel protein encoded by circASK1 ameliorates gefitinib resistance in lung adenocarcinoma by competitively activating ASK1-dependent apoptosis

Review on circular RNAs and new insights into their roles in cancer

(2021) Xiaozhu Tang et al.   Computational and Structural Biotechnology Journal

Molecular Mechanisms Driving mRNA Degradation by m6A Modification

(2020) Yujin Lee et al.   TRENDS IN GENETICS

Abnormally activated OPN/integrin αVβ3/FAK signalling is responsible for EGFR-TKI resistance in EGFR mutant non-small-cell lung cancer

(2020) Yulong Fu et al.   Journal of Hematology & Oncology

FGFR1 Cooperates with EGFR in Lung Cancer Oncogenesis, and Their Combined Inhibition Shows Improved Efficacy

(2019) Alvaro Quintanal-Villalonga et al.   Journal of Thoracic Oncology

EGFR-Mutated Lung Cancers Resistant to Osimertinib through EGFR C797S Respond to First-Generation Reversible EGFR Inhibitors but Eventually Acquire EGFR T790M/C797S in Preclinical Models and Clinical Samples

(2019) Deepa Rangachari et al.   Journal of Thoracic Oncology

A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1

(2019) Xin Xia et al.   Molecular Cancer

The biogenesis, biology and characterization of circular RNAs

(2019) Lasse S. Kristensen et al.   NATURE REVIEWS GENETICS

Distinct functions of AKT isoforms in breast cancer: a comprehensive review

(2019) Nico Hinz et al.   Cell Communication and Signaling

Engineering, delivery, and biological validation of artificial microRNA clusters for gene therapy applications

(2019) Vivek Bhaskaran et al.   Nature Protocols

m6A mRNA methylation initiated by METTL3 directly promotes YAP translation and increases YAP activity by regulating the MALAT1-miR-1914-3p-YAP axis to induce NSCLC drug resistance and metastasis

(2019) Dan Jin et al.   Journal of Hematology & Oncology

Pharmacological Inhibition of NOS Activates ASK1/JNK Pathway Augmenting Docetaxel-Mediated Apoptosis in Triple-Negative Breast Cancer

(2018) Daniel Dávila-González et al.   CLINICAL CANCER RESEARCH

A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis

(2018) Maolei Zhang et al.   ONCOGENE

Lung cancer: current therapies and new targeted treatments

(2017) Fred R Hirsch et al.   LANCET

Identifying and Characterizing circRNA-Protein Interaction

(2017) William W Du et al.   Theranostics

Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs

(2017) Chan Zhou et al.   Cell Reports

AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1.IMPLICATION OF AKT2 IN CHEMORESISTANCE.

(2016) Zeng-qiang Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overcoming drug resistance to receptor tyrosine kinase inhibitors: Learning from lung cancer

(2016) Michihiko Kuwano et al.   PHARMACOLOGY & THERAPEUTICS

Mechanisms of resistance to EGFR tyrosine kinase inhibitors

(2015) Lihua Huang et al.   Acta Pharmaceutica Sinica B

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Antitumor activity of selective MEK1/2 inhibitor AZD6244 in combination with PI3K/mTOR inhibitor BEZ235 in gefitinib-resistant NSCLC xenograft models

(2014) Yiqing Qu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase

(2011) Hayato Nakagawa et al.   HEPATOLOGY