Long non-coding RNAs are involved in alternative splicing and promote cancer progression

Noncoding RNAs regulate alternative splicing in Cancer

(2021) Yunze Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

ORAOV1-B Promotes OSCC Metastasis via the NF-κB-TNFα Loop

(2021) X. Luo et al.   JOURNAL OF DENTAL RESEARCH

The influence of circular RNAs on autophagy and disease progression

(2021) Yian Wang et al.   Autophagy

N6-methyladenosine-dependent signalling in cancer progression and insights into cancer therapies

(2021) Fenghua Tan et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

AFAP1-AS1: a rising star among oncogenic long non-coding RNAs

(2021) Fang Xiong et al.   Science China-Life Sciences

The long noncoding RNA AATBC promotes breast cancer migration and invasion by interacting with YBX1 and activating the YAP1/Hippo signaling pathway

(2021) Maonan Wang et al.   CANCER LETTERS

Epstein-Barr virus-encoded circular RNA circBART2.2 promotes immune escape of nasopharyngeal carcinoma by regulating PD-L1

(2021) Junshang Ge et al.   CANCER RESEARCH

LncRNA Ctcflos orchestrates transcription and alternative splicing in thermogenic adipogenesis

(2021) Andrea Bast‐Habersbrunner et al.   EMBO REPORTS

Aberrant Bcl-x splicing in cancer: from molecular mechanism to therapeutic modulation

(2021) Zhihui Dou et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

LINC01348 suppresses hepatocellular carcinoma metastasis through inhibition of SF3B3-mediated EZH2 pre-mRNA splicing

(2021) Yang-Hsiang Lin et al.   ONCOGENE

Abnormal X chromosome inactivation and tumor development

(2020) Dan Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hypoxia induced LUCAT1/PTBP1 axis modulates cancer cell viability and chemotherapy response

(2020) Lin Huan et al.   Molecular Cancer

Splicing dysregulation in cancer: from mechanistic understanding to a new class of therapeutic targets

(2020) Yongbo Wang et al.   Science China-Life Sciences

Epstein‐Barr virus‐encoded miR‐BART6‐3p inhibits cancer cell proliferation through the LOC553103‐STMN1 axis

(2020) Dan Wang et al.   FASEB JOURNAL

LncRNA AATBC regulates Pinin to promote metastasis in nasopharyngeal carcinoma

(2020) Ting Tang et al.   Molecular Oncology

Roles and mechanisms of alternative splicing in cancer — implications for care

(2020) Sophie C. Bonnal et al.   Nature Reviews Clinical Oncology

Small Protein Hidden in lncRNA LOC90024 Promotes “Cancerous” RNA Splicing and Tumorigenesis

(2020) Nan Meng et al.   Advanced Science

The Interaction Between lncRNA SNHG6 and hnRNPA1 Contributes to the Growth of Colorectal Cancer by Enhancing Aerobic Glycolysis Through the Regulation of Alternative Splicing of PKM

(2020) Zhixian Lan et al.   Frontiers in Oncology

Structure and expression of the long noncoding RNA gene MIR503 in humans and non-human primates

(2020) Ramesh Choudhari et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Comprehensive Network Analysis Reveals Alternative Splicing-Related lncRNAs in Hepatocellular Carcinoma

(2020) Junqing Wang et al.   Frontiers in Genetics

LncAS2Cancer: a comprehensive database for alternative splicing of lncRNAs across human cancers

(2020) Yulan Deng et al.   BRIEFINGS IN BIOINFORMATICS

EBV‐miR‐BART12 accelerates migration and invasion in EBV‐associated cancer cells by targeting tubulin polymerization‐promoting protein 1

(2020) Yingfen Wu et al.   FASEB JOURNAL

Emerging role of metabolic reprogramming in tumor immune evasion and immunotherapy

(2020) Chunmei Fan et al.   Science China-Life Sciences

Linc01232 promotes the metastasis of pancreatic cancer by suppressing the ubiquitin-mediated degradation of HNRNPA2B1 and activating the A-Raf-induced MAPK/ERK signaling pathway

(2020) Ling-Dong Meng et al.   CANCER LETTERS

circ MAN 1A2 could serve as a novel serum biomarker for malignant tumors

(2019) Chun‐Mei Fan et al.   CANCER SCIENCE

Long non-coding RNA PVT1 interacts with MYC and its downstream molecules to synergistically promote tumorigenesis

(2019) Ke Jin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

PVT1 Promotes Cancer Progression via MicroRNAs

(2019) Wenxi Wang et al.   Frontiers in Oncology

Identification of alternative splicing and lncRNA genes in pathogenesis of small cell lung cancer based on their RNA sequencing

(2019) Youming Lei et al.   Advances in Clinical and Experimental Medicine

LncRNA-encoded polypeptide ASRPS inhibits triple-negative breast cancer angiogenesis

(2019) Yirong Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Overexpressed long noncoding RNA CRNDE with distinct alternatively spliced isoforms in multiple cancers

(2018) Xuefei Ma et al.   Frontiers of Medicine

Long non-coding RNA LOC284454 promotes migration and invasion of nasopharyngeal carcinoma via modulating the Rho/Rac signaling pathway

(2018) Chunmei Fan et al.   CARCINOGENESIS

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway

(2018) Yu Lian et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The long non-coding RNA MALAT1 promotes ovarian cancer progression by regulating RBFOX2-mediated alternative splicing

(2018) Michael A. Gordon et al.   MOLECULAR CARCINOGENESIS

A Short Tandem Repeat-Enriched RNA Assembles a Nuclear Compartment to Control Alternative Splicing and Promote Cell Survival

(2018) Karen Yap et al.   MOLECULAR CELL

Production of Spliced Long Noncoding RNAs Specifies Regions with Increased Enhancer Activity

(2018) Noa Gil et al.   Cell Systems

Natural antisense transcript TPM1-AS regulates the alternative splicing of tropomyosin I through an interaction with RNA-binding motif protein 4

(2017) Guo-Wei Huang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Systematic identification of cancer-related long noncoding RNAs and aberrant alternative splicing of quintuple-negative lung adenocarcinoma through RNA-Seq

(2017) Lu Zhang et al.   LUNG CANCER

A Peptide Encoded by a Putative lncRNA HOXB-AS3 Suppresses Colon Cancer Growth

(2017) Jin-Zhou Huang et al.   MOLECULAR CELL

SR Proteins: Binders, Regulators, and Connectors of RNA

(2017) Sunjoo Jeong   MOLECULES AND CELLS

The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1

(2017) Ji-hang Yuan et al.   NATURE CELL BIOLOGY

A regulated PNUTS mRNA to lncRNA splice switch mediates EMT and tumour progression

(2017) Simon Grelet et al.   NATURE CELL BIOLOGY

lncRNA PVT1 and its splicing variant function as competing endogenous RNA to regulate clear cell renal cell carcinoma progression

(2017) Tao Yang et al.   Oncotarget

Long non-coding RNA LINC01133 inhibits epithelial–mesenchymal transition and metastasis in colorectal cancer by interacting with SRSF6

(2016) Jianlu Kong et al.   CANCER LETTERS

Long Noncoding RNA MALAT1 Promotes Hepatocellular Carcinoma Development by SRSF1 Upregulation and mTOR Activation

(2016) Pushkar Malakar et al.   CANCER RESEARCH

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2

(2016) Roxana S. Redis et al.   MOLECULAR CELL

Overexpression of the non-coding SOX2OT variants 4 and 7 in lung tumors suggests an oncogenic role in lung cancer

(2016) Marie Saghaeian Jazi et al.   TUMOR BIOLOGY

Regulation of alternative splicing of Bcl-x by BC200 contributes to breast cancer pathogenesis

(2016) R Singh et al.   Cell Death & Disease

Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage

(2016) Samar Alsafadi et al.   Nature Communications

Regulation of androgen receptor splice variant AR3 by PCGEM1

(2016) Ziqiang Zhang et al.   Oncotarget

Long noncoding RNA Saf and splicing factor 45 increase soluble Fas and resistance to apoptosis

(2016) Olga Villamizar et al.   Oncotarget

Identification of important long non-coding RNAs and highly recurrent aberrant alternative splicing events in hepatocellular carcinoma through integrative analysis of multiple RNA-Seq datasets

(2015) Lu Zhang et al.   MOLECULAR GENETICS AND GENOMICS

The landscape of long noncoding RNAs in the human transcriptome

(2015) Matthew K Iyer et al.   NATURE GENETICS

A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature

(2015) Inma Gonzalez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Long non-coding RNA and chromatin remodeling

(2015) Pei Han et al.   RNA Biology

A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature

(2015) Inma Gonzalez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

LncRNA: A link between RNA and cancer

(2014) Guodong Yang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Long non-coding RNA MALAT1 promotes tumour growth and metastasis in colorectal cancer through binding to SFPQ and releasing oncogene PTBP2 from SFPQ/PTBP2 complex

(2014) Q Ji et al.   BRITISH JOURNAL OF CANCER

MBNL proteins and their target RNAs, interaction and splicing regulation

(2014) Patryk Konieczny et al.   NUCLEIC ACIDS RESEARCH

LincRNA-uc002yug.2 involves in alternative splicing of RUNX1 and serves as a predictor for esophageal cancer and prognosis

(2014) H Wu et al.   ONCOGENE

The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing

(2013) G Barry et al.   MOLECULAR PSYCHIATRY

Alternative RNA splicing and cancer

(2013) Sali Liu et al.   Wiley Interdisciplinary Reviews-RNA

Reduced Expression of Fibroblast Growth Factor Receptor 2IIIb in Hepatocellular Carcinoma Induces a More Aggressive Growth

(2010) Thomas Amann et al.   AMERICAN JOURNAL OF PATHOLOGY

RNA traffic control of chromatin complexes

(2010) Magdalena J Koziol et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

(2010) Vidisha Tripathi et al.   MOLECULAR CELL

A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition

(2008) M. Beltran et al.   GENES & DEVELOPMENT

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE