The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1

Global Mapping of Human RNA-RNA Interactions

(2016) Eesha Sharma et al.   MOLECULAR CELL

Mechanisms and Regulation of Alternative Pre-mRNA Splicing

(2015) Yeon Lee et al.   Annual Review of Biochemistry

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis

(2015) Amal M. El-Naggar et al.   CANCER CELL

The Long Noncoding RNA lncTCF7 Promotes Self-Renewal of Human Liver Cancer Stem Cells through Activation of Wnt Signaling

(2015) Yanying Wang et al.   Cell Stem Cell

PKCε-mediated c-Met endosomal processing directs fluctuant c-Met-JNK-paxillin signaling for tumor progression of HepG2

(2015) Chi-Tan Hu et al.   CELLULAR SIGNALLING

Paxillin-dependent regulation of IGF2 and H19 gene cluster expression

(2015) P. Marasek et al.   JOURNAL OF CELL SCIENCE

ZIC2-dependent OCT4 activation drives self-renewal of human liver cancer stem cells

(2015) Pingping Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

(2015) Colleen A. McHugh et al.   NATURE

RNA-mediated epigenetic regulation of gene expression

(2015) Daniel Holoch et al.   NATURE REVIEWS GENETICS

Paxillin confers resistance to tyrosine kinase inhibitors in EGFR-mutant lung cancers via modulating BIM and Mcl-1 protein stability

(2015) D-W Wu et al.   ONCOGENE

PBX3 is targeted by multiple miRNAs and is essential for liver tumour-initiating cells

(2015) Haibo Han et al.   Nature Communications

Inhibition of vemurafenib-resistant melanoma by interference with pre-mRNA splicing

(2015) Maayan Salton et al.   Nature Communications

Expression of Paxillin is Correlated with Clinical Prognosis in Colorectal Cancer Patients

(2015) Min Gong   MEDICAL SCIENCE MONITOR

The Splicing Factor RBM4 Controls Apoptosis, Proliferation, and Migration to Suppress Tumor Progression

(2014) Yang Wang et al.   CANCER CELL

A Long Noncoding RNA Activated by TGF-β Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma

(2014) Ji-hang Yuan et al.   CANCER CELL

Paxillin promotes tumor progression and predicts survival and relapse in oral cavity squamous cell carcinoma by microRNA-218 targeting

(2014) De-Wei Wu et al.   CARCINOGENESIS

Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2

(2014) Fang Wang et al.   HEPATOLOGY

Transcriptome-wide Landscape of Pre-mRNA Alternative Splicing Associated with Metastatic Colonization

(2014) Zhi-xiang Lu et al.   MOLECULAR CANCER RESEARCH

mTORC1-mediated translational elongation limits intestinal tumour initiation and growth

(2014) William J. Faller et al.   NATURE

1B50-1, a mAb Raised against Recurrent Tumor Cells, Targets Liver Tumor-Initiating Cells by Binding to the Calcium Channel α2δ1 Subunit

(2013) Wei Zhao et al.   CANCER CELL

MUC15 Inhibits Dimerization of EGFR and PI3K–AKT Signaling and Is Associated With Aggressive Hepatocellular Carcinomas in Patients

(2013) Ruo–Yu Wang et al.   GASTROENTEROLOGY

Prognostic Gene Expression Signature for Patients With Hepatitis C–Related Early-Stage Cirrhosis

(2013) Yujin Hoshida et al.   GASTROENTEROLOGY

Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice

(2013) Michael G. Poulos et al.   HUMAN MOLECULAR GENETICS

RBM5, 6, and 10 Differentially Regulate NUMB Alternative Splicing to Control Cancer Cell Proliferation

(2013) Elias G. Bechara et al.   MOLECULAR CELL

MBNL proteins repress ES-cell-specific alternative splicing and reprogramming

(2013) Hong Han et al.   NATURE

Long non-coding RNAs: new players in cell differentiation and development

(2013) Alessandro Fatica et al.   NATURE REVIEWS GENETICS

Alternative splicing: a pivotal step between eukaryotic transcription and translation

(2013) Alberto R. Kornblihtt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Oncofetal Gene SALL4 in Aggressive Hepatocellular Carcinoma

(2013) Kol Jia Yong et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hallmarks of alternative splicing in cancer

(2013) S Oltean et al.   ONCOGENE

Misregulation of Pre-mRNA Alternative Splicing in Cancer

(2013) J. Zhang et al.   Cancer Discovery

Transcriptional ontogeny of the developing liver

(2012) Janice S Lee et al.   BMC GENOMICS

Overexpression of paxillin induced by miR-137 suppression promotes tumor progression and metastasis in colorectal cancer

(2012) Dong-Liang Chen et al.   CARCINOGENESIS

Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins

(2012) Eric T. Wang et al.   CELL

Nanog regulates self-renewal of cancer stem cells through the insulin-like growth factor pathway in human hepatocellular carcinoma

(2012) Juanjuan Shan et al.   HEPATOLOGY

Paxillin mediates extranuclear and intranuclear signaling in prostate cancer proliferation

(2012) Aritro Sen et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic signatures shared in embryonic liver development and liver cancer define prognostically relevant subgroups in HCC

(2012) Diana Becker et al.   Molecular Cancer

LincRNA-p21 Suppresses Target mRNA Translation

(2012) Je-Hyun Yoon et al.   MOLECULAR CELL

Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat

(2012) Claudia Carrieri et al.   NATURE

Focal Adhesion Kinase (FAK) Mediates the Induction of Pro-Oncogenic and Fibrogenic Phenotypes in Hepatitis C Virus (HCV)-Infected Cells

(2012) Anna Alisi et al.   PLoS One

CD24+ Liver Tumor-Initiating Cells Drive Self-Renewal and Tumor Initiation through STAT3-Mediated NANOG Regulation

(2011) Terence Kin Wah Lee et al.   Cell Stem Cell

Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma

(2011) Edmund Kwok-Kwan Tung et al.   LIVER INTERNATIONAL

A Unique Metastasis Gene Signature Enables Prediction of Tumor Relapse in Early-Stage Hepatocellular Carcinoma Patients

(2010) S. Roessler et al.   CANCER RESEARCH

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Multi-stage analysis of gene expression and transcription regulation in C57/B6 mouse liver development

(2008) Tingting Li et al.   GENOMICS

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase

(2008) Mohammad Ali Faghihi et al.   NATURE MEDICINE

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart

(2008) A. Kalsotra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA