MutationalPatterns: the one stop shop for the analysis of mutational processes

Antiviral treatment causes a unique mutational signature in cancers of transplantation recipients

(2021) Jurrian K. de Kanter et al.   Cell Stem Cell

De novo mutational signature discovery in tumor genomes using SparseSignatures

(2021) Avantika Lal et al.   PLoS Computational Biology

Database resources of the national center for biotechnology information

(2021) Eric W Sayers et al.   NUCLEIC ACIDS RESEARCH

V(D)J recombination, somatic hypermutation and class switch recombination of immunoglobulins: mechanism and regulation

(2020) Xiying Chi et al.   IMMUNOLOGY

Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli

(2020) Cayetano Pleguezuelos-Manzano et al.   NATURE

Pan-cancer analysis of whole genomes

(2020)   NATURE

The repertoire of mutational signatures in human cancer

(2020) Ludmil B. Alexandrov et al.   NATURE

Systematic comparison of somatic variant calling performance among different sequencing depth and mutation frequency

(2020) Zixi Chen et al.   Scientific Reports

Pervasive lesion segregation shapes cancer genome evolution

(2020) Sarah J. Aitken et al.   NATURE

Expanded encyclopaedias of DNA elements in the human and mouse genomes

(2020) Jill E. Moore et al.   NATURE

XPC deficiency increases risk of hematologic malignancies through mutator phenotype and characteristic mutational signature

(2020) Andrey A. Yurchenko et al.   Nature Communications

Local Determinants of the Mutational Landscape of the Human Genome

(2019) Abel Gonzalez-Perez et al.   CELL

A Compendium of Mutational Signatures of Environmental Agents

(2019) Jill E. Kucab et al.   CELL

decompTumor2Sig: identification of mutational signatures active in individual tumors

(2019) Sandra Krüger et al.   BMC BIOINFORMATICS

Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer

(2019) Myrthe Jager et al.   GENOME RESEARCH

Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features

(2019) Rémi Buisson et al.   SCIENCE

A practical guide for mutational signature analysis in hematological malignancies

(2019) Francesco Maura et al.   Nature Communications

Pan-cancer whole-genome analyses of metastatic solid tumours

(2019) Peter Priestley et al.   NATURE

Heterochromatin protein 1α interacts with parallel RNA and DNA G-quadruplexes

(2019) Ruby J Roach et al.   NUCLEIC ACIDS RESEARCH

MutationalPatterns: comprehensive genome-wide analysis of mutational processes

(2018) Francis Blokzijl et al.   Genome Medicine

Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours

(2018) Xiaotu Ma et al.   NATURE

Maftools: efficient and comprehensive analysis of somatic variants in cancer

(2018) Anand Mayakonda et al.   GENOME RESEARCH

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

(2017) Helen Davies et al.   NATURE MEDICINE

signeR: an empirical Bayesian approach to mutational signature discovery

(2016) Rafael A. Rosales et al.   BIOINFORMATICS

Tissue-specific mutation accumulation in human adult stem cells during life

(2016) Francis Blokzijl et al.   NATURE

Cell-of-origin chromatin organization shapes the mutational landscape of cancer

(2015) Paz Polak et al.   NATURE

Clock-like mutational processes in human somatic cells

(2015) Ludmil B Alexandrov et al.   NATURE GENETICS

The Ensembl Regulatory Build

(2015) Daniel R Zerbino et al.   GENOME BIOLOGY

Mechanisms underlying mutational signatures in human cancers

(2014) Thomas Helleday et al.   NATURE REVIEWS GENETICS

Base Excision Repair Facilitates a Functional Relationship Between Guanine Oxidation and Histone Demethylation

(2013) Jianfeng Li et al.   ANTIOXIDANTS & REDOX SIGNALING

Deciphering Signatures of Mutational Processes Operative in Human Cancer

(2013) Ludmil B. Alexandrov et al.   Cell Reports

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers

(2009) Peter C. Fong et al.   NEW ENGLAND JOURNAL OF MEDICINE